| Full name: tubulin beta 2A class IIa | Alias Symbol: dJ40E16.7 | ||
| Type: protein-coding gene | Cytoband: 6p25.2 | ||
| Entrez ID: 7280 | HGNC ID: HGNC:12412 | Ensembl Gene: ENSG00000137267 | OMIM ID: 615101 |
| Drug and gene relationship at DGIdb | |||
TUBB2A involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05130 | Pathogenic Escherichia coli infection |
Expression of TUBB2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TUBB2A | 7280 | 204141_at | -0.5868 | 0.3285 | |
| GSE20347 | TUBB2A | 7280 | 204141_at | -1.2588 | 0.0000 | |
| GSE23400 | TUBB2A | 7280 | 204141_at | -0.6373 | 0.0000 | |
| GSE26886 | TUBB2A | 7280 | 204141_at | -0.3192 | 0.4591 | |
| GSE29001 | TUBB2A | 7280 | 204141_at | -0.9694 | 0.0144 | |
| GSE38129 | TUBB2A | 7280 | 204141_at | -1.0261 | 0.0000 | |
| GSE45670 | TUBB2A | 7280 | 204141_at | -0.0003 | 0.9994 | |
| GSE53622 | TUBB2A | 7280 | 34903 | -1.1441 | 0.0000 | |
| GSE53624 | TUBB2A | 7280 | 34903 | -0.6826 | 0.0000 | |
| GSE63941 | TUBB2A | 7280 | 204141_at | -2.0484 | 0.0741 | |
| GSE77861 | TUBB2A | 7280 | 204141_at | -0.2883 | 0.5949 | |
| GSE97050 | TUBB2A | 7280 | A_33_P3365002 | -0.2485 | 0.2317 | |
| SRP007169 | TUBB2A | 7280 | RNAseq | -2.4476 | 0.0000 | |
| SRP008496 | TUBB2A | 7280 | RNAseq | -2.0309 | 0.0000 | |
| SRP064894 | TUBB2A | 7280 | RNAseq | -0.2894 | 0.4043 | |
| SRP133303 | TUBB2A | 7280 | RNAseq | -0.5791 | 0.0320 | |
| SRP159526 | TUBB2A | 7280 | RNAseq | -0.6980 | 0.1265 | |
| SRP193095 | TUBB2A | 7280 | RNAseq | -0.6766 | 0.0003 | |
| SRP219564 | TUBB2A | 7280 | RNAseq | -0.8253 | 0.0125 | |
| TCGA | TUBB2A | 7280 | RNAseq | -0.0309 | 0.7909 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by TUBB2A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TUBB2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TUBB2A | 7280 | 4 | 5 | 21 | |
| GSE20123 | TUBB2A | 7280 | 4 | 5 | 21 | |
| GSE43470 | TUBB2A | 7280 | 8 | 4 | 31 | |
| GSE46452 | TUBB2A | 7280 | 1 | 10 | 48 | |
| GSE47630 | TUBB2A | 7280 | 7 | 8 | 25 | |
| GSE54993 | TUBB2A | 7280 | 1 | 1 | 68 | |
| GSE54994 | TUBB2A | 7280 | 10 | 3 | 40 | |
| GSE60625 | TUBB2A | 7280 | 0 | 1 | 10 | |
| GSE74703 | TUBB2A | 7280 | 7 | 3 | 26 | |
| GSE74704 | TUBB2A | 7280 | 2 | 2 | 16 | |
| TCGA | TUBB2A | 7280 | 17 | 30 | 49 |
Total number of gains: 61; Total number of losses: 72; Total Number of normals: 355.
Somatic mutations of TUBB2A:
Generating mutation plots.
Highly correlated genes for TUBB2A:
Showing top 20/700 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TUBB2A | WSB1 | 0.807994 | 3 | 0 | 3 |
| TUBB2A | BDP1 | 0.772194 | 3 | 0 | 3 |
| TUBB2A | OCM2 | 0.74574 | 3 | 0 | 3 |
| TUBB2A | UBE2J1 | 0.739312 | 3 | 0 | 3 |
| TUBB2A | ITPRIP | 0.731571 | 6 | 0 | 6 |
| TUBB2A | CLASP2 | 0.725287 | 3 | 0 | 3 |
| TUBB2A | ZNF460 | 0.721982 | 3 | 0 | 3 |
| TUBB2A | RASSF3 | 0.713454 | 3 | 0 | 3 |
| TUBB2A | PELO | 0.710453 | 3 | 0 | 3 |
| TUBB2A | MRPS25 | 0.709753 | 3 | 0 | 3 |
| TUBB2A | S1PR1 | 0.706626 | 3 | 0 | 3 |
| TUBB2A | HSDL2 | 0.706616 | 6 | 0 | 5 |
| TUBB2A | THOC7 | 0.703052 | 6 | 0 | 5 |
| TUBB2A | CCNH | 0.69966 | 5 | 0 | 4 |
| TUBB2A | RARS2 | 0.697305 | 3 | 0 | 3 |
| TUBB2A | CNOT6 | 0.694985 | 3 | 0 | 3 |
| TUBB2A | ARF1 | 0.68951 | 3 | 0 | 3 |
| TUBB2A | TAF9B | 0.687435 | 3 | 0 | 3 |
| TUBB2A | ILK | 0.676606 | 3 | 0 | 3 |
| TUBB2A | RAB18 | 0.676586 | 4 | 0 | 3 |
For details and further investigation, click here
