| Full name: crystallin zeta | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 1429 | HGNC ID: HGNC:2419 | Ensembl Gene: ENSG00000116791 | OMIM ID: 123691 |
| Drug and gene relationship at DGIdb | |||
Expression of CRYZ:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRYZ | 1429 | 202950_at | -0.7103 | 0.4138 | |
| GSE20347 | CRYZ | 1429 | 202950_at | -0.4340 | 0.0142 | |
| GSE23400 | CRYZ | 1429 | 202950_at | 0.0939 | 0.3902 | |
| GSE26886 | CRYZ | 1429 | 202950_at | -0.4519 | 0.2158 | |
| GSE29001 | CRYZ | 1429 | 202950_at | -0.2715 | 0.4262 | |
| GSE38129 | CRYZ | 1429 | 202950_at | -0.3795 | 0.0109 | |
| GSE45670 | CRYZ | 1429 | 202950_at | -0.3328 | 0.1470 | |
| GSE53622 | CRYZ | 1429 | 37433 | -0.3497 | 0.0003 | |
| GSE53624 | CRYZ | 1429 | 37433 | -0.4524 | 0.0000 | |
| GSE63941 | CRYZ | 1429 | 202950_at | 0.1559 | 0.8467 | |
| GSE77861 | CRYZ | 1429 | 202950_at | -0.6001 | 0.0823 | |
| GSE97050 | CRYZ | 1429 | A_33_P3391476 | -0.5333 | 0.3215 | |
| SRP007169 | CRYZ | 1429 | RNAseq | -0.0680 | 0.8675 | |
| SRP008496 | CRYZ | 1429 | RNAseq | -0.0510 | 0.8846 | |
| SRP064894 | CRYZ | 1429 | RNAseq | -0.1094 | 0.6431 | |
| SRP133303 | CRYZ | 1429 | RNAseq | -0.0260 | 0.8959 | |
| SRP159526 | CRYZ | 1429 | RNAseq | -0.7437 | 0.0097 | |
| SRP193095 | CRYZ | 1429 | RNAseq | -0.7530 | 0.0001 | |
| SRP219564 | CRYZ | 1429 | RNAseq | -0.5828 | 0.1713 | |
| TCGA | CRYZ | 1429 | RNAseq | -0.1244 | 0.1110 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CRYZ expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRYZ:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRYZ | 1429 | 0 | 7 | 23 | |
| GSE20123 | CRYZ | 1429 | 0 | 7 | 23 | |
| GSE43470 | CRYZ | 1429 | 4 | 2 | 37 | |
| GSE46452 | CRYZ | 1429 | 0 | 1 | 58 | |
| GSE47630 | CRYZ | 1429 | 8 | 6 | 26 | |
| GSE54993 | CRYZ | 1429 | 0 | 0 | 70 | |
| GSE54994 | CRYZ | 1429 | 6 | 4 | 43 | |
| GSE60625 | CRYZ | 1429 | 0 | 0 | 11 | |
| GSE74703 | CRYZ | 1429 | 3 | 2 | 31 | |
| GSE74704 | CRYZ | 1429 | 0 | 4 | 16 | |
| TCGA | CRYZ | 1429 | 8 | 24 | 64 |
Total number of gains: 29; Total number of losses: 57; Total Number of normals: 402.
Somatic mutations of CRYZ:
Generating mutation plots.
Highly correlated genes for CRYZ:
Showing top 20/353 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRYZ | PTPRG | 0.803919 | 3 | 0 | 3 |
| CRYZ | ITPRIP | 0.756497 | 3 | 0 | 3 |
| CRYZ | CYB5B | 0.743072 | 3 | 0 | 3 |
| CRYZ | BDP1 | 0.740726 | 3 | 0 | 3 |
| CRYZ | WDR20 | 0.740359 | 3 | 0 | 3 |
| CRYZ | VPS29 | 0.737669 | 4 | 0 | 3 |
| CRYZ | PITPNM3 | 0.719645 | 3 | 0 | 3 |
| CRYZ | CLDND1 | 0.712472 | 3 | 0 | 3 |
| CRYZ | PTPN12 | 0.711945 | 3 | 0 | 3 |
| CRYZ | PHF13 | 0.699732 | 3 | 0 | 3 |
| CRYZ | STAM | 0.696982 | 3 | 0 | 3 |
| CRYZ | PNPLA8 | 0.695524 | 3 | 0 | 3 |
| CRYZ | SNCA | 0.687192 | 4 | 0 | 3 |
| CRYZ | STAU2 | 0.685953 | 4 | 0 | 3 |
| CRYZ | PFKFB3 | 0.673492 | 3 | 0 | 3 |
| CRYZ | MAPK9 | 0.670122 | 3 | 0 | 3 |
| CRYZ | KIAA1191 | 0.669488 | 4 | 0 | 3 |
| CRYZ | TMEM106B | 0.667252 | 4 | 0 | 3 |
| CRYZ | MTX3 | 0.66672 | 4 | 0 | 3 |
| CRYZ | MPI | 0.665419 | 4 | 0 | 3 |
For details and further investigation, click here
