| Full name: biliverdin reductase B | Alias Symbol: SDR43U1 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 645 | HGNC ID: HGNC:1063 | Ensembl Gene: ENSG00000090013 | OMIM ID: 600941 |
| Drug and gene relationship at DGIdb | |||
Expression of BLVRB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BLVRB | 645 | 202201_at | -0.9946 | 0.1609 | |
| GSE20347 | BLVRB | 645 | 202201_at | -1.3074 | 0.0000 | |
| GSE23400 | BLVRB | 645 | 202201_at | -1.1577 | 0.0000 | |
| GSE26886 | BLVRB | 645 | 202201_at | -2.0700 | 0.0000 | |
| GSE29001 | BLVRB | 645 | 202201_at | -2.2088 | 0.0001 | |
| GSE38129 | BLVRB | 645 | 202201_at | -1.1167 | 0.0000 | |
| GSE45670 | BLVRB | 645 | 202201_at | -0.5556 | 0.0420 | |
| GSE53622 | BLVRB | 645 | 91203 | -1.7199 | 0.0000 | |
| GSE53624 | BLVRB | 645 | 91203 | -1.5637 | 0.0000 | |
| GSE63941 | BLVRB | 645 | 202201_at | 1.2250 | 0.0163 | |
| GSE77861 | BLVRB | 645 | 202201_at | -0.7124 | 0.0331 | |
| GSE97050 | BLVRB | 645 | A_33_P3360728 | -0.5401 | 0.1927 | |
| SRP007169 | BLVRB | 645 | RNAseq | -3.7606 | 0.0000 | |
| SRP008496 | BLVRB | 645 | RNAseq | -3.3526 | 0.0000 | |
| SRP064894 | BLVRB | 645 | RNAseq | -1.8238 | 0.0000 | |
| SRP133303 | BLVRB | 645 | RNAseq | -1.0770 | 0.0005 | |
| SRP159526 | BLVRB | 645 | RNAseq | -0.9338 | 0.0457 | |
| SRP193095 | BLVRB | 645 | RNAseq | -1.6189 | 0.0000 | |
| SRP219564 | BLVRB | 645 | RNAseq | -1.3980 | 0.0026 | |
| TCGA | BLVRB | 645 | RNAseq | -0.1544 | 0.0723 |
Upregulated datasets: 1; Downregulated datasets: 13.
Survival by BLVRB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BLVRB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BLVRB | 645 | 6 | 5 | 19 | |
| GSE20123 | BLVRB | 645 | 6 | 4 | 20 | |
| GSE43470 | BLVRB | 645 | 3 | 9 | 31 | |
| GSE46452 | BLVRB | 645 | 48 | 1 | 10 | |
| GSE47630 | BLVRB | 645 | 9 | 5 | 26 | |
| GSE54993 | BLVRB | 645 | 17 | 4 | 49 | |
| GSE54994 | BLVRB | 645 | 8 | 9 | 36 | |
| GSE60625 | BLVRB | 645 | 9 | 0 | 2 | |
| GSE74703 | BLVRB | 645 | 3 | 6 | 27 | |
| GSE74704 | BLVRB | 645 | 6 | 2 | 12 | |
| TCGA | BLVRB | 645 | 14 | 16 | 66 |
Total number of gains: 129; Total number of losses: 61; Total Number of normals: 298.
Somatic mutations of BLVRB:
Generating mutation plots.
Highly correlated genes for BLVRB:
Showing top 20/1273 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BLVRB | NCCRP1 | 0.830673 | 3 | 0 | 3 |
| BLVRB | SCNN1B | 0.820848 | 11 | 0 | 11 |
| BLVRB | TOM1 | 0.818265 | 10 | 0 | 10 |
| BLVRB | LRP10 | 0.806315 | 10 | 0 | 10 |
| BLVRB | MAPK3 | 0.802022 | 11 | 0 | 11 |
| BLVRB | FCHO2 | 0.797289 | 6 | 0 | 6 |
| BLVRB | VSIG10L | 0.796432 | 8 | 0 | 7 |
| BLVRB | SPINK7 | 0.795648 | 7 | 0 | 7 |
| BLVRB | SLURP1 | 0.794478 | 11 | 0 | 11 |
| BLVRB | PRSS27 | 0.794138 | 7 | 0 | 7 |
| BLVRB | UBL3 | 0.787269 | 11 | 0 | 11 |
| BLVRB | KRT78 | 0.787078 | 7 | 0 | 7 |
| BLVRB | PLEKHM1 | 0.786018 | 10 | 0 | 10 |
| BLVRB | LYNX1 | 0.785852 | 7 | 0 | 7 |
| BLVRB | CRABP2 | 0.785211 | 11 | 0 | 11 |
| BLVRB | BNIPL | 0.7825 | 7 | 0 | 7 |
| BLVRB | GDPD3 | 0.782127 | 11 | 0 | 11 |
| BLVRB | GYS2 | 0.781242 | 10 | 0 | 10 |
| BLVRB | CYSRT1 | 0.779303 | 6 | 0 | 6 |
| BLVRB | NLRX1 | 0.778214 | 9 | 0 | 9 |
For details and further investigation, click here
