| Full name: basic leucine zipper nuclear factor 1 | Alias Symbol: JEM-1 | ||
| Type: protein-coding gene | Cytoband: 1q24.2 | ||
| Entrez ID: 8548 | HGNC ID: HGNC:1065 | Ensembl Gene: ENSG00000117475 | OMIM ID: 608692 |
| Drug and gene relationship at DGIdb | |||
Expression of BLZF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BLZF1 | 8548 | 203840_at | -0.7327 | 0.0879 | |
| GSE20347 | BLZF1 | 8548 | 203840_at | -1.0581 | 0.0000 | |
| GSE23400 | BLZF1 | 8548 | 210462_at | -0.1198 | 0.0006 | |
| GSE26886 | BLZF1 | 8548 | 203840_at | -1.2491 | 0.0000 | |
| GSE29001 | BLZF1 | 8548 | 203840_at | -0.7221 | 0.1997 | |
| GSE38129 | BLZF1 | 8548 | 203840_at | -0.8299 | 0.0000 | |
| GSE45670 | BLZF1 | 8548 | 203840_at | -0.1695 | 0.5111 | |
| GSE53622 | BLZF1 | 8548 | 90903 | -0.5974 | 0.0000 | |
| GSE53624 | BLZF1 | 8548 | 90903 | -0.7844 | 0.0000 | |
| GSE63941 | BLZF1 | 8548 | 203840_at | -0.6316 | 0.2066 | |
| GSE77861 | BLZF1 | 8548 | 203840_at | -1.0312 | 0.0046 | |
| GSE97050 | BLZF1 | 8548 | A_24_P119259 | -0.2338 | 0.5830 | |
| SRP007169 | BLZF1 | 8548 | RNAseq | -2.1489 | 0.0000 | |
| SRP008496 | BLZF1 | 8548 | RNAseq | -1.8005 | 0.0000 | |
| SRP064894 | BLZF1 | 8548 | RNAseq | -1.3245 | 0.0000 | |
| SRP133303 | BLZF1 | 8548 | RNAseq | -0.4848 | 0.0003 | |
| SRP159526 | BLZF1 | 8548 | RNAseq | -1.1287 | 0.0021 | |
| SRP193095 | BLZF1 | 8548 | RNAseq | -0.9469 | 0.0000 | |
| SRP219564 | BLZF1 | 8548 | RNAseq | -1.0939 | 0.0335 | |
| TCGA | BLZF1 | 8548 | RNAseq | 0.0125 | 0.8404 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by BLZF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BLZF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BLZF1 | 8548 | 11 | 1 | 18 | |
| GSE20123 | BLZF1 | 8548 | 11 | 1 | 18 | |
| GSE43470 | BLZF1 | 8548 | 7 | 2 | 34 | |
| GSE46452 | BLZF1 | 8548 | 3 | 1 | 55 | |
| GSE47630 | BLZF1 | 8548 | 14 | 0 | 26 | |
| GSE54993 | BLZF1 | 8548 | 0 | 6 | 64 | |
| GSE54994 | BLZF1 | 8548 | 16 | 0 | 37 | |
| GSE60625 | BLZF1 | 8548 | 0 | 0 | 11 | |
| GSE74703 | BLZF1 | 8548 | 7 | 2 | 27 | |
| GSE74704 | BLZF1 | 8548 | 5 | 0 | 15 | |
| TCGA | BLZF1 | 8548 | 43 | 3 | 50 |
Total number of gains: 117; Total number of losses: 16; Total Number of normals: 355.
Somatic mutations of BLZF1:
Generating mutation plots.
Highly correlated genes for BLZF1:
Showing top 20/1061 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BLZF1 | ZNF557 | 0.814509 | 3 | 0 | 3 |
| BLZF1 | CCNYL1 | 0.77295 | 5 | 0 | 5 |
| BLZF1 | CAST | 0.763599 | 10 | 0 | 10 |
| BLZF1 | ACAA1 | 0.757977 | 8 | 0 | 8 |
| BLZF1 | BRWD1 | 0.75221 | 4 | 0 | 4 |
| BLZF1 | EPG5 | 0.750621 | 4 | 0 | 4 |
| BLZF1 | GBP6 | 0.732444 | 4 | 0 | 4 |
| BLZF1 | RNF11 | 0.724614 | 11 | 0 | 11 |
| BLZF1 | RASSF3 | 0.722805 | 3 | 0 | 3 |
| BLZF1 | IL18 | 0.722115 | 10 | 0 | 9 |
| BLZF1 | TMOD3 | 0.721154 | 10 | 0 | 10 |
| BLZF1 | PDCD4 | 0.717838 | 4 | 0 | 4 |
| BLZF1 | KRT78 | 0.714393 | 6 | 0 | 6 |
| BLZF1 | CYSRT1 | 0.714194 | 6 | 0 | 5 |
| BLZF1 | MACC1 | 0.713868 | 4 | 0 | 4 |
| BLZF1 | UBE2E1 | 0.713628 | 11 | 0 | 11 |
| BLZF1 | PHYHIPL | 0.712992 | 3 | 0 | 3 |
| BLZF1 | HIGD1A | 0.710476 | 11 | 0 | 10 |
| BLZF1 | PRADC1 | 0.707796 | 3 | 0 | 3 |
| BLZF1 | TMEM79 | 0.69927 | 6 | 0 | 5 |
For details and further investigation, click here
