| Full name: biphenyl hydrolase like | Alias Symbol: Bph-rp|VACVase | ||
| Type: protein-coding gene | Cytoband: 6p25.2 | ||
| Entrez ID: 670 | HGNC ID: HGNC:1094 | Ensembl Gene: ENSG00000137274 | OMIM ID: 603156 |
| Drug and gene relationship at DGIdb | |||
Expression of BPHL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BPHL | 670 | 205750_at | 0.3218 | 0.4047 | |
| GSE20347 | BPHL | 670 | 205750_at | 0.0679 | 0.6232 | |
| GSE23400 | BPHL | 670 | 205750_at | 0.0797 | 0.0639 | |
| GSE26886 | BPHL | 670 | 205750_at | -0.0568 | 0.8096 | |
| GSE29001 | BPHL | 670 | 205750_at | -0.0096 | 0.9617 | |
| GSE38129 | BPHL | 670 | 205750_at | 0.2399 | 0.0310 | |
| GSE45670 | BPHL | 670 | 205750_at | 0.0910 | 0.4578 | |
| GSE53622 | BPHL | 670 | 28486 | 0.0113 | 0.9064 | |
| GSE53624 | BPHL | 670 | 28486 | -0.0792 | 0.2928 | |
| GSE63941 | BPHL | 670 | 205750_at | 0.3838 | 0.4823 | |
| GSE77861 | BPHL | 670 | 205750_at | 0.1405 | 0.3864 | |
| GSE97050 | BPHL | 670 | A_23_P42087 | -0.2017 | 0.3810 | |
| SRP007169 | BPHL | 670 | RNAseq | 0.1321 | 0.7974 | |
| SRP008496 | BPHL | 670 | RNAseq | 0.2567 | 0.4992 | |
| SRP064894 | BPHL | 670 | RNAseq | 0.5122 | 0.0770 | |
| SRP133303 | BPHL | 670 | RNAseq | -0.1140 | 0.4572 | |
| SRP159526 | BPHL | 670 | RNAseq | 0.1812 | 0.6674 | |
| SRP193095 | BPHL | 670 | RNAseq | -0.5349 | 0.0000 | |
| SRP219564 | BPHL | 670 | RNAseq | -0.1341 | 0.6926 | |
| TCGA | BPHL | 670 | RNAseq | 0.0211 | 0.7911 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BPHL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BPHL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BPHL | 670 | 4 | 5 | 21 | |
| GSE20123 | BPHL | 670 | 4 | 5 | 21 | |
| GSE43470 | BPHL | 670 | 8 | 4 | 31 | |
| GSE46452 | BPHL | 670 | 1 | 10 | 48 | |
| GSE47630 | BPHL | 670 | 7 | 8 | 25 | |
| GSE54993 | BPHL | 670 | 1 | 1 | 68 | |
| GSE54994 | BPHL | 670 | 10 | 3 | 40 | |
| GSE60625 | BPHL | 670 | 0 | 1 | 10 | |
| GSE74703 | BPHL | 670 | 7 | 3 | 26 | |
| GSE74704 | BPHL | 670 | 2 | 2 | 16 | |
| TCGA | BPHL | 670 | 17 | 30 | 49 |
Total number of gains: 61; Total number of losses: 72; Total Number of normals: 355.
Somatic mutations of BPHL:
Generating mutation plots.
Highly correlated genes for BPHL:
Showing top 20/159 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BPHL | XXYLT1 | 0.756831 | 3 | 0 | 3 |
| BPHL | SURF6 | 0.720337 | 3 | 0 | 3 |
| BPHL | RFWD3 | 0.711809 | 3 | 0 | 3 |
| BPHL | G2E3 | 0.710485 | 3 | 0 | 3 |
| BPHL | UBAP2L | 0.708547 | 3 | 0 | 3 |
| BPHL | EWSR1 | 0.707131 | 4 | 0 | 3 |
| BPHL | SPIRE2 | 0.701324 | 3 | 0 | 3 |
| BPHL | PIGM | 0.691927 | 3 | 0 | 3 |
| BPHL | NUCKS1 | 0.690857 | 3 | 0 | 3 |
| BPHL | TAF1C | 0.688892 | 3 | 0 | 3 |
| BPHL | DPY19L2 | 0.686925 | 3 | 0 | 3 |
| BPHL | DFFA | 0.686726 | 3 | 0 | 3 |
| BPHL | CBL | 0.686245 | 3 | 0 | 3 |
| BPHL | ATP6V0B | 0.682167 | 3 | 0 | 3 |
| BPHL | TMEM51 | 0.681994 | 3 | 0 | 3 |
| BPHL | ZNF830 | 0.676635 | 3 | 0 | 3 |
| BPHL | MTO1 | 0.674739 | 4 | 0 | 3 |
| BPHL | NUP188 | 0.670729 | 3 | 0 | 3 |
| BPHL | TYW5 | 0.666734 | 3 | 0 | 3 |
| BPHL | RAD21 | 0.664369 | 3 | 0 | 3 |
For details and further investigation, click here
