| Full name: coiled-coil domain containing 170 | Alias Symbol: FLJ23305|bA282P11.1 | ||
| Type: protein-coding gene | Cytoband: 6q25.1 | ||
| Entrez ID: 80129 | HGNC ID: HGNC:21177 | Ensembl Gene: ENSG00000120262 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC170:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC170 | 80129 | 220581_at | 0.0341 | 0.9193 | |
| GSE20347 | CCDC170 | 80129 | 220581_at | 0.0232 | 0.8127 | |
| GSE23400 | CCDC170 | 80129 | 220581_at | -0.0195 | 0.6003 | |
| GSE26886 | CCDC170 | 80129 | 220581_at | -0.0676 | 0.6150 | |
| GSE29001 | CCDC170 | 80129 | 220581_at | 0.0644 | 0.6775 | |
| GSE38129 | CCDC170 | 80129 | 220581_at | -0.0819 | 0.3009 | |
| GSE45670 | CCDC170 | 80129 | 220581_at | 0.0085 | 0.9317 | |
| GSE53622 | CCDC170 | 80129 | 10640 | 0.3677 | 0.0008 | |
| GSE53624 | CCDC170 | 80129 | 10640 | 0.2296 | 0.0051 | |
| GSE63941 | CCDC170 | 80129 | 220581_at | -1.4835 | 0.0000 | |
| GSE77861 | CCDC170 | 80129 | 220581_at | -0.0154 | 0.8868 | |
| SRP007169 | CCDC170 | 80129 | RNAseq | 1.6344 | 0.0822 | |
| SRP064894 | CCDC170 | 80129 | RNAseq | 0.9570 | 0.0022 | |
| SRP133303 | CCDC170 | 80129 | RNAseq | 0.4592 | 0.0446 | |
| SRP159526 | CCDC170 | 80129 | RNAseq | 0.2832 | 0.6310 | |
| SRP193095 | CCDC170 | 80129 | RNAseq | -0.2294 | 0.4435 | |
| SRP219564 | CCDC170 | 80129 | RNAseq | 0.6016 | 0.2286 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CCDC170 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CCDC170:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC170 | 80129 | 1 | 4 | 25 | |
| GSE20123 | CCDC170 | 80129 | 1 | 3 | 26 | |
| GSE43470 | CCDC170 | 80129 | 4 | 0 | 39 | |
| GSE46452 | CCDC170 | 80129 | 3 | 10 | 46 | |
| GSE47630 | CCDC170 | 80129 | 9 | 4 | 27 | |
| GSE54993 | CCDC170 | 80129 | 3 | 2 | 65 | |
| GSE54994 | CCDC170 | 80129 | 8 | 8 | 37 | |
| GSE60625 | CCDC170 | 80129 | 0 | 1 | 10 | |
| GSE74703 | CCDC170 | 80129 | 4 | 0 | 32 | |
| GSE74704 | CCDC170 | 80129 | 0 | 1 | 19 | |
| TCGA | CCDC170 | 80129 | 12 | 20 | 64 |
Total number of gains: 45; Total number of losses: 53; Total Number of normals: 390.
Somatic mutations of CCDC170:
Generating mutation plots.
Highly correlated genes for CCDC170:
Showing top 20/345 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC170 | TMEM119 | 0.705043 | 3 | 0 | 3 |
| CCDC170 | TMPRSS5 | 0.689778 | 5 | 0 | 5 |
| CCDC170 | ATG10 | 0.689517 | 4 | 0 | 4 |
| CCDC170 | CCL13 | 0.68896 | 3 | 0 | 3 |
| CCDC170 | CLIP3 | 0.686567 | 3 | 0 | 3 |
| CCDC170 | PF4 | 0.677785 | 4 | 0 | 3 |
| CCDC170 | CHRM2 | 0.67309 | 5 | 0 | 5 |
| CCDC170 | GATA4 | 0.663383 | 3 | 0 | 3 |
| CCDC170 | KHDRBS2 | 0.659263 | 5 | 0 | 5 |
| CCDC170 | BRINP1 | 0.654833 | 4 | 0 | 3 |
| CCDC170 | SLC4A4 | 0.653269 | 5 | 0 | 5 |
| CCDC170 | SH2B3 | 0.650313 | 4 | 0 | 4 |
| CCDC170 | TNFSF4 | 0.648279 | 3 | 0 | 3 |
| CCDC170 | PDCD1 | 0.64304 | 4 | 0 | 3 |
| CCDC170 | CDH7 | 0.642359 | 5 | 0 | 4 |
| CCDC170 | ERN1 | 0.641524 | 3 | 0 | 3 |
| CCDC170 | ZNF197 | 0.636249 | 5 | 0 | 3 |
| CCDC170 | ABCB8 | 0.636101 | 3 | 0 | 3 |
| CCDC170 | S1PR4 | 0.635614 | 4 | 0 | 4 |
| CCDC170 | TMEM200A | 0.633804 | 3 | 0 | 3 |
For details and further investigation, click here
