| Full name: collagen type IX alpha 3 chain | Alias Symbol: IDD|MED|EDM3|FLJ90759|DJ885L7.4.1 | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 1299 | HGNC ID: HGNC:2219 | Ensembl Gene: ENSG00000092758 | OMIM ID: 120270 |
| Drug and gene relationship at DGIdb | |||
COL9A3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04151 | PI3K-Akt signaling pathway | |
| hsa04510 | Focal adhesion |
Expression of COL9A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COL9A3 | 1299 | 204724_s_at | 0.7063 | 0.4562 | |
| GSE20347 | COL9A3 | 1299 | 204724_s_at | 0.8682 | 0.0013 | |
| GSE23400 | COL9A3 | 1299 | 204724_s_at | 0.0966 | 0.2204 | |
| GSE26886 | COL9A3 | 1299 | 204724_s_at | 1.6413 | 0.0002 | |
| GSE29001 | COL9A3 | 1299 | 204724_s_at | 1.0854 | 0.0780 | |
| GSE38129 | COL9A3 | 1299 | 204724_s_at | 0.9565 | 0.0051 | |
| GSE45670 | COL9A3 | 1299 | 204724_s_at | 0.0443 | 0.8872 | |
| GSE53622 | COL9A3 | 1299 | 36080 | 0.7676 | 0.0031 | |
| GSE53624 | COL9A3 | 1299 | 36080 | 0.7886 | 0.0000 | |
| GSE63941 | COL9A3 | 1299 | 204724_s_at | 1.4592 | 0.2165 | |
| GSE77861 | COL9A3 | 1299 | 204724_s_at | 0.1434 | 0.3862 | |
| GSE97050 | COL9A3 | 1299 | A_23_P40108 | 0.0835 | 0.8736 | |
| SRP064894 | COL9A3 | 1299 | RNAseq | -0.0546 | 0.8590 | |
| SRP133303 | COL9A3 | 1299 | RNAseq | 0.2216 | 0.6983 | |
| SRP219564 | COL9A3 | 1299 | RNAseq | 2.0083 | 0.0695 | |
| TCGA | COL9A3 | 1299 | RNAseq | 0.1080 | 0.7544 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by COL9A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COL9A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COL9A3 | 1299 | 14 | 2 | 14 | |
| GSE20123 | COL9A3 | 1299 | 14 | 2 | 14 | |
| GSE43470 | COL9A3 | 1299 | 11 | 1 | 31 | |
| GSE46452 | COL9A3 | 1299 | 35 | 0 | 24 | |
| GSE47630 | COL9A3 | 1299 | 25 | 1 | 14 | |
| GSE54993 | COL9A3 | 1299 | 0 | 16 | 54 | |
| GSE54994 | COL9A3 | 1299 | 29 | 0 | 24 | |
| GSE60625 | COL9A3 | 1299 | 0 | 0 | 11 | |
| GSE74703 | COL9A3 | 1299 | 10 | 0 | 26 | |
| GSE74704 | COL9A3 | 1299 | 11 | 0 | 9 | |
| TCGA | COL9A3 | 1299 | 43 | 4 | 49 |
Total number of gains: 192; Total number of losses: 26; Total Number of normals: 270.
Somatic mutations of COL9A3:
Generating mutation plots.
Highly correlated genes for COL9A3:
Showing top 20/219 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COL9A3 | BTG3 | 0.681337 | 3 | 0 | 3 |
| COL9A3 | NME3 | 0.664788 | 3 | 0 | 3 |
| COL9A3 | IFT43 | 0.663844 | 4 | 0 | 3 |
| COL9A3 | FBXO2 | 0.653193 | 3 | 0 | 3 |
| COL9A3 | TNFRSF10B | 0.652547 | 3 | 0 | 3 |
| COL9A3 | GJA1 | 0.651609 | 3 | 0 | 3 |
| COL9A3 | EMILIN3 | 0.649993 | 3 | 0 | 3 |
| COL9A3 | MAGEA11 | 0.643409 | 3 | 0 | 3 |
| COL9A3 | CASK | 0.629694 | 3 | 0 | 3 |
| COL9A3 | CHST3 | 0.627818 | 5 | 0 | 5 |
| COL9A3 | ST6GALNAC2 | 0.620417 | 3 | 0 | 3 |
| COL9A3 | OBSL1 | 0.620001 | 5 | 0 | 4 |
| COL9A3 | PATZ1 | 0.619067 | 6 | 0 | 4 |
| COL9A3 | ENTPD6 | 0.618084 | 3 | 0 | 3 |
| COL9A3 | ARHGEF40 | 0.613659 | 7 | 0 | 4 |
| COL9A3 | POFUT2 | 0.611763 | 6 | 0 | 5 |
| COL9A3 | POLE | 0.610078 | 4 | 0 | 3 |
| COL9A3 | LGALS8 | 0.606716 | 4 | 0 | 4 |
| COL9A3 | LGSN | 0.606652 | 4 | 0 | 3 |
| COL9A3 | PPP1R1C | 0.606217 | 4 | 0 | 3 |
For details and further investigation, click here
