| Full name: basic leucine zipper and W2 domains 1 | Alias Symbol: BZAP45|KIAA0005 | ||
| Type: protein-coding gene | Cytoband: 2q33.1 | ||
| Entrez ID: 9689 | HGNC ID: HGNC:18380 | Ensembl Gene: ENSG00000082153 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of BZW1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BZW1 | 9689 | 200777_s_at | 0.2257 | 0.4374 | |
| GSE20347 | BZW1 | 9689 | 200777_s_at | -0.3244 | 0.0585 | |
| GSE23400 | BZW1 | 9689 | 200777_s_at | -0.1181 | 0.1603 | |
| GSE26886 | BZW1 | 9689 | 200777_s_at | -0.9485 | 0.0000 | |
| GSE29001 | BZW1 | 9689 | 200777_s_at | -0.4942 | 0.0668 | |
| GSE38129 | BZW1 | 9689 | 200777_s_at | -0.0088 | 0.9660 | |
| GSE45670 | BZW1 | 9689 | 200777_s_at | 0.3039 | 0.0078 | |
| GSE53622 | BZW1 | 9689 | 106088 | -0.1271 | 0.1325 | |
| GSE53624 | BZW1 | 9689 | 106088 | -0.4554 | 0.0000 | |
| GSE63941 | BZW1 | 9689 | 200776_s_at | 0.9137 | 0.0338 | |
| GSE77861 | BZW1 | 9689 | 200777_s_at | 0.1630 | 0.4841 | |
| GSE97050 | BZW1 | 9689 | A_33_P3334548 | 0.2883 | 0.4787 | |
| SRP007169 | BZW1 | 9689 | RNAseq | -1.6757 | 0.0001 | |
| SRP008496 | BZW1 | 9689 | RNAseq | -1.3548 | 0.0000 | |
| SRP064894 | BZW1 | 9689 | RNAseq | -0.6182 | 0.0007 | |
| SRP133303 | BZW1 | 9689 | RNAseq | 0.1744 | 0.3739 | |
| SRP159526 | BZW1 | 9689 | RNAseq | -0.3807 | 0.0093 | |
| SRP193095 | BZW1 | 9689 | RNAseq | -0.6661 | 0.0001 | |
| SRP219564 | BZW1 | 9689 | RNAseq | -0.8057 | 0.0167 | |
| TCGA | BZW1 | 9689 | RNAseq | 0.0886 | 0.0419 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by BZW1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BZW1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BZW1 | 9689 | 6 | 4 | 20 | |
| GSE20123 | BZW1 | 9689 | 6 | 4 | 20 | |
| GSE43470 | BZW1 | 9689 | 2 | 1 | 40 | |
| GSE46452 | BZW1 | 9689 | 1 | 4 | 54 | |
| GSE47630 | BZW1 | 9689 | 4 | 5 | 31 | |
| GSE54993 | BZW1 | 9689 | 0 | 3 | 67 | |
| GSE54994 | BZW1 | 9689 | 10 | 8 | 35 | |
| GSE60625 | BZW1 | 9689 | 0 | 3 | 8 | |
| GSE74703 | BZW1 | 9689 | 2 | 1 | 33 | |
| GSE74704 | BZW1 | 9689 | 3 | 2 | 15 | |
| TCGA | BZW1 | 9689 | 22 | 11 | 63 |
Total number of gains: 56; Total number of losses: 46; Total Number of normals: 386.
Somatic mutations of BZW1:
Generating mutation plots.
Highly correlated genes for BZW1:
Showing top 20/624 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BZW1 | REST | 0.775536 | 3 | 0 | 3 |
| BZW1 | AASDHPPT | 0.77235 | 3 | 0 | 3 |
| BZW1 | GLUD2 | 0.740282 | 4 | 0 | 4 |
| BZW1 | RTN4IP1 | 0.72981 | 3 | 0 | 3 |
| BZW1 | PSMC2 | 0.728531 | 3 | 0 | 3 |
| BZW1 | TRAPPC6B | 0.724674 | 3 | 0 | 3 |
| BZW1 | ATP6V1B2 | 0.720323 | 4 | 0 | 4 |
| BZW1 | PAK1IP1 | 0.72016 | 3 | 0 | 3 |
| BZW1 | TP53RK | 0.711695 | 3 | 0 | 3 |
| BZW1 | EIF2S2 | 0.710342 | 5 | 0 | 4 |
| BZW1 | CATSPER1 | 0.706413 | 3 | 0 | 3 |
| BZW1 | NAA35 | 0.705583 | 4 | 0 | 3 |
| BZW1 | ELOVL1 | 0.705033 | 3 | 0 | 3 |
| BZW1 | FOPNL | 0.701916 | 3 | 0 | 3 |
| BZW1 | PAIP2 | 0.701228 | 3 | 0 | 3 |
| BZW1 | SRRD | 0.701175 | 3 | 0 | 3 |
| BZW1 | SEC61B | 0.70043 | 4 | 0 | 3 |
| BZW1 | TSPAN5 | 0.696118 | 4 | 0 | 3 |
| BZW1 | SRPK1 | 0.690634 | 5 | 0 | 5 |
| BZW1 | PHB | 0.690421 | 3 | 0 | 3 |
For details and further investigation, click here
