PSMC2

 

Full name: proteasome 26S subunit, ATPase 2 Alias Symbol: MSS1|S7|Nbla10058
Type: protein-coding gene Cytoband: 7q22.1
Entrez ID: 5701 HGNC ID: HGNC:9548 Ensembl Gene: ENSG00000161057 OMIM ID: 154365
Drug and gene relationship at DGIdb

 

Expression of PSMC2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PSMC2 5701 201068_s_at 0.4309 0.0791
GSE20347 PSMC2 5701 201068_s_at 0.6967 0.0001
GSE23400 PSMC2 5701 201068_s_at 0.6710 0.0000
GSE26886 PSMC2 5701 201068_s_at -0.1197 0.5396
GSE29001 PSMC2 5701 201068_s_at 0.5269 0.0039
GSE38129 PSMC2 5701 201068_s_at 0.7474 0.0000
GSE45670 PSMC2 5701 201068_s_at 0.5047 0.0007
GSE53622 PSMC2 5701 40280 0.6489 0.0000
GSE53624 PSMC2 5701 40280 0.7132 0.0000
GSE63941 PSMC2 5701 201068_s_at 0.0245 0.9602
GSE77861 PSMC2 5701 201068_s_at 0.5140 0.0121
GSE97050 PSMC2 5701 A_23_P304287 0.2878 0.3527
SRP007169 PSMC2 5701 RNAseq 0.1960 0.5798
SRP008496 PSMC2 5701 RNAseq 0.6383 0.0306
SRP064894 PSMC2 5701 RNAseq 0.4839 0.0009
SRP133303 PSMC2 5701 RNAseq 0.6563 0.0004
SRP159526 PSMC2 5701 RNAseq 0.3194 0.2485
SRP193095 PSMC2 5701 RNAseq 0.4386 0.0032
SRP219564 PSMC2 5701 RNAseq 0.2517 0.4327
TCGA PSMC2 5701 RNAseq 0.2458 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by PSMC2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PSMC2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PSMC2 5701 13 0 17
GSE20123 PSMC2 5701 13 0 17
GSE43470 PSMC2 5701 6 1 36
GSE46452 PSMC2 5701 10 1 48
GSE47630 PSMC2 5701 7 3 30
GSE54993 PSMC2 5701 1 10 59
GSE54994 PSMC2 5701 15 3 35
GSE60625 PSMC2 5701 0 0 11
GSE74703 PSMC2 5701 6 1 29
GSE74704 PSMC2 5701 9 0 11
TCGA PSMC2 5701 54 6 36

Total number of gains: 134; Total number of losses: 25; Total Number of normals: 329.  

 

Somatic mutations of PSMC2:

 

Generating mutation plots.

 

Highly correlated genes for PSMC2:

 

Showing top 20/1971 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PSMC2ORAI10.791517303
PSMC2PTCD10.7652303
PSMC2MCM70.7650471009
PSMC2POP70.76180512012
PSMC2DNAJC20.75359612012
PSMC2NOP560.7505303
PSMC2ORC50.7490912012
PSMC2PYCR20.748689303
PSMC2ACTL6A0.74679411011
PSMC2RPL39L0.74285810010
PSMC2CBX30.740801909
PSMC2SNAP470.740041303
PSMC2CKS1B0.73996911010
PSMC2FOXM10.738301909
PSMC2CCT50.737849909
PSMC2CDK40.7377410010
PSMC2RFC40.73695611011
PSMC2MRPL30.73445810010
PSMC2PBK0.73298110010
PSMC2HSPD10.73104410010

For details and further investigation, click here