| Full name: heat shock protein family A (Hsp70) member 4 like | Alias Symbol: APG-1|Osp94|HSPH3 | ||
| Type: protein-coding gene | Cytoband: 4q28.1 | ||
| Entrez ID: 22824 | HGNC ID: HGNC:17041 | Ensembl Gene: ENSG00000164070 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HSPA4L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HSPA4L | 22824 | 205543_at | -0.4151 | 0.7917 | |
| GSE20347 | HSPA4L | 22824 | 205543_at | -0.4925 | 0.0502 | |
| GSE23400 | HSPA4L | 22824 | 205543_at | -0.0095 | 0.9447 | |
| GSE26886 | HSPA4L | 22824 | 205543_at | -0.5807 | 0.0817 | |
| GSE29001 | HSPA4L | 22824 | 205543_at | -0.5647 | 0.1481 | |
| GSE38129 | HSPA4L | 22824 | 205543_at | -0.0342 | 0.9296 | |
| GSE45670 | HSPA4L | 22824 | 205543_at | 0.1443 | 0.5833 | |
| GSE53622 | HSPA4L | 22824 | 91674 | -0.5995 | 0.0001 | |
| GSE53624 | HSPA4L | 22824 | 91674 | -0.6105 | 0.0000 | |
| GSE63941 | HSPA4L | 22824 | 205543_at | 1.1855 | 0.0987 | |
| GSE77861 | HSPA4L | 22824 | 205543_at | 0.0632 | 0.8330 | |
| GSE97050 | HSPA4L | 22824 | A_23_P363936 | -0.1643 | 0.7646 | |
| SRP007169 | HSPA4L | 22824 | RNAseq | 0.1387 | 0.8063 | |
| SRP008496 | HSPA4L | 22824 | RNAseq | -0.1875 | 0.6290 | |
| SRP064894 | HSPA4L | 22824 | RNAseq | -0.8477 | 0.0058 | |
| SRP133303 | HSPA4L | 22824 | RNAseq | -0.1163 | 0.6984 | |
| SRP159526 | HSPA4L | 22824 | RNAseq | -0.6128 | 0.2250 | |
| SRP193095 | HSPA4L | 22824 | RNAseq | -0.3529 | 0.2023 | |
| SRP219564 | HSPA4L | 22824 | RNAseq | -1.1969 | 0.0469 | |
| TCGA | HSPA4L | 22824 | RNAseq | 0.3318 | 0.0037 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by HSPA4L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HSPA4L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HSPA4L | 22824 | 0 | 12 | 18 | |
| GSE20123 | HSPA4L | 22824 | 0 | 12 | 18 | |
| GSE43470 | HSPA4L | 22824 | 0 | 13 | 30 | |
| GSE46452 | HSPA4L | 22824 | 1 | 36 | 22 | |
| GSE47630 | HSPA4L | 22824 | 0 | 22 | 18 | |
| GSE54993 | HSPA4L | 22824 | 9 | 0 | 61 | |
| GSE54994 | HSPA4L | 22824 | 1 | 11 | 41 | |
| GSE60625 | HSPA4L | 22824 | 0 | 1 | 10 | |
| GSE74703 | HSPA4L | 22824 | 0 | 11 | 25 | |
| GSE74704 | HSPA4L | 22824 | 0 | 6 | 14 | |
| TCGA | HSPA4L | 22824 | 8 | 35 | 53 |
Total number of gains: 19; Total number of losses: 159; Total Number of normals: 310.
Somatic mutations of HSPA4L:
Generating mutation plots.
Highly correlated genes for HSPA4L:
Showing top 20/515 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HSPA4L | ASCC3 | 0.75122 | 5 | 0 | 5 |
| HSPA4L | TBC1D23 | 0.722668 | 3 | 0 | 3 |
| HSPA4L | TAF12 | 0.702653 | 4 | 0 | 3 |
| HSPA4L | DUSP18 | 0.702351 | 3 | 0 | 3 |
| HSPA4L | C11orf80 | 0.70159 | 3 | 0 | 3 |
| HSPA4L | TVP23B | 0.688798 | 4 | 0 | 4 |
| HSPA4L | MGAT4B | 0.682155 | 3 | 0 | 3 |
| HSPA4L | ZNF83 | 0.68039 | 3 | 0 | 3 |
| HSPA4L | AKIP1 | 0.677873 | 4 | 0 | 3 |
| HSPA4L | SLC35A3 | 0.675309 | 5 | 0 | 4 |
| HSPA4L | PKN3 | 0.673608 | 3 | 0 | 3 |
| HSPA4L | SS18 | 0.672097 | 4 | 0 | 3 |
| HSPA4L | RAB18 | 0.666705 | 4 | 0 | 3 |
| HSPA4L | IER3IP1 | 0.666474 | 4 | 0 | 3 |
| HSPA4L | COG5 | 0.66607 | 4 | 0 | 3 |
| HSPA4L | RFC1 | 0.656837 | 3 | 0 | 3 |
| HSPA4L | ENTPD3 | 0.656306 | 4 | 0 | 4 |
| HSPA4L | JMJD1C | 0.65396 | 4 | 0 | 3 |
| HSPA4L | MRPS22 | 0.653043 | 5 | 0 | 5 |
| HSPA4L | DNAJC1 | 0.652196 | 4 | 0 | 3 |
For details and further investigation, click here
