| Full name: EDAR associated death domain | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q42.3-q43 | ||
| Entrez ID: 128178 | HGNC ID: HGNC:14341 | Ensembl Gene: ENSG00000186197 | OMIM ID: 606603 |
| Drug and gene relationship at DGIdb | |||
Expression of EDARADD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EDARADD | 128178 | 1553430_a_at | 0.6354 | 0.4899 | |
| GSE26886 | EDARADD | 128178 | 1553430_a_at | -0.1078 | 0.4065 | |
| GSE45670 | EDARADD | 128178 | 1553430_a_at | 0.0441 | 0.5988 | |
| GSE53622 | EDARADD | 128178 | 23510 | 0.8486 | 0.0000 | |
| GSE53624 | EDARADD | 128178 | 23510 | 0.7914 | 0.0000 | |
| GSE63941 | EDARADD | 128178 | 1553430_a_at | 1.8791 | 0.0684 | |
| GSE77861 | EDARADD | 128178 | 1553430_a_at | 0.1210 | 0.2912 | |
| GSE97050 | EDARADD | 128178 | A_23_P503233 | 0.5747 | 0.1608 | |
| SRP007169 | EDARADD | 128178 | RNAseq | 1.5154 | 0.0175 | |
| SRP008496 | EDARADD | 128178 | RNAseq | 1.0638 | 0.0107 | |
| SRP064894 | EDARADD | 128178 | RNAseq | 0.8909 | 0.0044 | |
| SRP133303 | EDARADD | 128178 | RNAseq | 0.9419 | 0.0066 | |
| SRP159526 | EDARADD | 128178 | RNAseq | -0.3264 | 0.5010 | |
| SRP193095 | EDARADD | 128178 | RNAseq | 0.3531 | 0.1867 | |
| SRP219564 | EDARADD | 128178 | RNAseq | 0.6419 | 0.4002 | |
| TCGA | EDARADD | 128178 | RNAseq | 0.1147 | 0.3412 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by EDARADD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EDARADD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EDARADD | 128178 | 10 | 1 | 19 | |
| GSE20123 | EDARADD | 128178 | 11 | 1 | 18 | |
| GSE43470 | EDARADD | 128178 | 8 | 1 | 34 | |
| GSE46452 | EDARADD | 128178 | 4 | 2 | 53 | |
| GSE47630 | EDARADD | 128178 | 15 | 0 | 25 | |
| GSE54993 | EDARADD | 128178 | 0 | 6 | 64 | |
| GSE54994 | EDARADD | 128178 | 16 | 0 | 37 | |
| GSE60625 | EDARADD | 128178 | 0 | 0 | 11 | |
| GSE74703 | EDARADD | 128178 | 8 | 1 | 27 | |
| GSE74704 | EDARADD | 128178 | 5 | 0 | 15 | |
| TCGA | EDARADD | 128178 | 43 | 4 | 49 |
Total number of gains: 120; Total number of losses: 16; Total Number of normals: 352.
Somatic mutations of EDARADD:
Generating mutation plots.
Highly correlated genes for EDARADD:
Showing top 20/175 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EDARADD | PARS2 | 0.725645 | 3 | 0 | 3 |
| EDARADD | SMARCB1 | 0.715627 | 3 | 0 | 3 |
| EDARADD | GRB7 | 0.71488 | 3 | 0 | 3 |
| EDARADD | CNPY3 | 0.708279 | 3 | 0 | 3 |
| EDARADD | SNRPC | 0.679151 | 3 | 0 | 3 |
| EDARADD | ZNF385A | 0.67477 | 4 | 0 | 3 |
| EDARADD | NSUN5 | 0.67079 | 4 | 0 | 4 |
| EDARADD | CDCA8 | 0.669067 | 4 | 0 | 3 |
| EDARADD | PAFAH1B3 | 0.665495 | 4 | 0 | 3 |
| EDARADD | POLQ | 0.660711 | 3 | 0 | 3 |
| EDARADD | SMARCD1 | 0.660088 | 3 | 0 | 3 |
| EDARADD | MCM5 | 0.659868 | 5 | 0 | 4 |
| EDARADD | PGS1 | 0.659419 | 4 | 0 | 3 |
| EDARADD | CPXM1 | 0.65918 | 3 | 0 | 3 |
| EDARADD | USP31 | 0.65651 | 3 | 0 | 3 |
| EDARADD | ZDHHC23 | 0.654839 | 3 | 0 | 3 |
| EDARADD | TARBP2 | 0.653479 | 5 | 0 | 4 |
| EDARADD | NDC1 | 0.653417 | 3 | 0 | 3 |
| EDARADD | FOXM1 | 0.651433 | 5 | 0 | 5 |
| EDARADD | C19orf48 | 0.647303 | 3 | 0 | 3 |
For details and further investigation, click here
