| Full name: chromosome 14 open reading frame 28 | Alias Symbol: DRIP-1 | ||
| Type: protein-coding gene | Cytoband: 14q21.2 | ||
| Entrez ID: 122525 | HGNC ID: HGNC:19834 | Ensembl Gene: ENSG00000179476 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C14orf28:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C14orf28 | 122525 | 235369_at | -1.0922 | 0.0774 | |
| GSE26886 | C14orf28 | 122525 | 235369_at | -0.8704 | 0.0004 | |
| GSE45670 | C14orf28 | 122525 | 235369_at | -1.3980 | 0.0000 | |
| GSE53622 | C14orf28 | 122525 | 2672 | -0.8132 | 0.0000 | |
| GSE53624 | C14orf28 | 122525 | 2672 | -0.7318 | 0.0000 | |
| GSE63941 | C14orf28 | 122525 | 238647_at | -0.3951 | 0.5987 | |
| GSE77861 | C14orf28 | 122525 | 235369_at | -0.1925 | 0.1487 | |
| GSE97050 | C14orf28 | 122525 | A_33_P3395758 | -0.3368 | 0.3274 | |
| SRP007169 | C14orf28 | 122525 | RNAseq | -0.1871 | 0.7959 | |
| SRP064894 | C14orf28 | 122525 | RNAseq | -0.4454 | 0.0071 | |
| SRP133303 | C14orf28 | 122525 | RNAseq | -0.7394 | 0.0054 | |
| SRP159526 | C14orf28 | 122525 | RNAseq | -0.9939 | 0.0067 | |
| SRP193095 | C14orf28 | 122525 | RNAseq | -0.7911 | 0.0000 | |
| SRP219564 | C14orf28 | 122525 | RNAseq | -1.0380 | 0.0241 | |
| TCGA | C14orf28 | 122525 | RNAseq | -0.3620 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by C14orf28 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C14orf28:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C14orf28 | 122525 | 6 | 5 | 19 | |
| GSE20123 | C14orf28 | 122525 | 6 | 5 | 19 | |
| GSE43470 | C14orf28 | 122525 | 8 | 3 | 32 | |
| GSE46452 | C14orf28 | 122525 | 17 | 2 | 40 | |
| GSE47630 | C14orf28 | 122525 | 11 | 10 | 19 | |
| GSE54993 | C14orf28 | 122525 | 3 | 9 | 58 | |
| GSE54994 | C14orf28 | 122525 | 18 | 5 | 30 | |
| GSE60625 | C14orf28 | 122525 | 0 | 2 | 9 | |
| GSE74703 | C14orf28 | 122525 | 7 | 3 | 26 | |
| GSE74704 | C14orf28 | 122525 | 3 | 3 | 14 | |
| TCGA | C14orf28 | 122525 | 31 | 14 | 51 |
Total number of gains: 110; Total number of losses: 61; Total Number of normals: 317.
Somatic mutations of C14orf28:
Generating mutation plots.
Highly correlated genes for C14orf28:
Showing top 20/1066 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C14orf28 | CHRDL1 | 0.841547 | 4 | 0 | 4 |
| C14orf28 | TCEAL1 | 0.799883 | 4 | 0 | 4 |
| C14orf28 | CPED1 | 0.799368 | 3 | 0 | 3 |
| C14orf28 | FXYD1 | 0.775442 | 3 | 0 | 3 |
| C14orf28 | BTC | 0.774204 | 6 | 0 | 6 |
| C14orf28 | TIMP3 | 0.772582 | 3 | 0 | 3 |
| C14orf28 | RNASE4 | 0.772085 | 3 | 0 | 3 |
| C14orf28 | SCN7A | 0.765911 | 5 | 0 | 5 |
| C14orf28 | NEGR1 | 0.764676 | 5 | 0 | 4 |
| C14orf28 | MYOCD | 0.756325 | 6 | 0 | 6 |
| C14orf28 | ANGPTL1 | 0.755823 | 5 | 0 | 5 |
| C14orf28 | TCF21 | 0.74899 | 4 | 0 | 4 |
| C14orf28 | KLHL15 | 0.748609 | 4 | 0 | 4 |
| C14orf28 | CBX7 | 0.747892 | 6 | 0 | 6 |
| C14orf28 | OMD | 0.744171 | 3 | 0 | 3 |
| C14orf28 | ID4 | 0.740853 | 4 | 0 | 4 |
| C14orf28 | DPT | 0.738908 | 5 | 0 | 4 |
| C14orf28 | NME5 | 0.733791 | 4 | 0 | 4 |
| C14orf28 | KCNB1 | 0.733514 | 4 | 0 | 4 |
| C14orf28 | PID1 | 0.732366 | 4 | 0 | 4 |
For details and further investigation, click here
