| Full name: exonuclease 3'-5' domain containing 2 | Alias Symbol: FLJ10738 | ||
| Type: protein-coding gene | Cytoband: 14q24.1 | ||
| Entrez ID: 55218 | HGNC ID: HGNC:20217 | Ensembl Gene: ENSG00000081177 | OMIM ID: 616940 |
| Drug and gene relationship at DGIdb | |||
Expression of EXD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EXD2 | 55218 | 218363_at | -0.2949 | 0.3636 | |
| GSE20347 | EXD2 | 55218 | 218363_at | -0.3240 | 0.0202 | |
| GSE23400 | EXD2 | 55218 | 218363_at | -0.0360 | 0.4878 | |
| GSE26886 | EXD2 | 55218 | 218363_at | -1.3227 | 0.0000 | |
| GSE29001 | EXD2 | 55218 | 218363_at | -0.1330 | 0.5341 | |
| GSE38129 | EXD2 | 55218 | 218363_at | -0.3741 | 0.0004 | |
| GSE45670 | EXD2 | 55218 | 218363_at | 0.0653 | 0.6770 | |
| GSE53622 | EXD2 | 55218 | 8632 | -0.0273 | 0.7680 | |
| GSE53624 | EXD2 | 55218 | 8632 | -0.2458 | 0.0009 | |
| GSE63941 | EXD2 | 55218 | 218363_at | 1.2184 | 0.0027 | |
| GSE77861 | EXD2 | 55218 | 218363_at | -0.2925 | 0.3408 | |
| GSE97050 | EXD2 | 55218 | A_23_P205293 | -0.0714 | 0.8414 | |
| SRP007169 | EXD2 | 55218 | RNAseq | -0.5085 | 0.2202 | |
| SRP008496 | EXD2 | 55218 | RNAseq | -0.3367 | 0.2520 | |
| SRP064894 | EXD2 | 55218 | RNAseq | 0.0125 | 0.9326 | |
| SRP133303 | EXD2 | 55218 | RNAseq | -0.2296 | 0.1592 | |
| SRP159526 | EXD2 | 55218 | RNAseq | -0.1449 | 0.6966 | |
| SRP193095 | EXD2 | 55218 | RNAseq | -0.3035 | 0.0060 | |
| SRP219564 | EXD2 | 55218 | RNAseq | 0.0755 | 0.8009 | |
| TCGA | EXD2 | 55218 | RNAseq | -0.1054 | 0.0522 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by EXD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EXD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EXD2 | 55218 | 8 | 3 | 19 | |
| GSE20123 | EXD2 | 55218 | 8 | 3 | 19 | |
| GSE43470 | EXD2 | 55218 | 8 | 3 | 32 | |
| GSE46452 | EXD2 | 55218 | 16 | 3 | 40 | |
| GSE47630 | EXD2 | 55218 | 11 | 9 | 20 | |
| GSE54993 | EXD2 | 55218 | 3 | 9 | 58 | |
| GSE54994 | EXD2 | 55218 | 18 | 5 | 30 | |
| GSE60625 | EXD2 | 55218 | 0 | 2 | 9 | |
| GSE74703 | EXD2 | 55218 | 7 | 3 | 26 | |
| GSE74704 | EXD2 | 55218 | 3 | 3 | 14 | |
| TCGA | EXD2 | 55218 | 32 | 16 | 48 |
Total number of gains: 114; Total number of losses: 59; Total Number of normals: 315.
Somatic mutations of EXD2:
Generating mutation plots.
Highly correlated genes for EXD2:
Showing top 20/339 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EXD2 | POGK | 0.755946 | 3 | 0 | 3 |
| EXD2 | USP21 | 0.753544 | 3 | 0 | 3 |
| EXD2 | PRPF38A | 0.745429 | 3 | 0 | 3 |
| EXD2 | HLCS | 0.73652 | 3 | 0 | 3 |
| EXD2 | OPHN1 | 0.735796 | 3 | 0 | 3 |
| EXD2 | RCAN3 | 0.728243 | 3 | 0 | 3 |
| EXD2 | TRA2A | 0.726999 | 3 | 0 | 3 |
| EXD2 | APOB | 0.71725 | 3 | 0 | 3 |
| EXD2 | PITPNM3 | 0.716009 | 4 | 0 | 3 |
| EXD2 | OXNAD1 | 0.708381 | 3 | 0 | 3 |
| EXD2 | MPP7 | 0.705824 | 4 | 0 | 4 |
| EXD2 | FAM83D | 0.700424 | 4 | 0 | 4 |
| EXD2 | C15orf41 | 0.699123 | 3 | 0 | 3 |
| EXD2 | CDKN2C | 0.698052 | 3 | 0 | 3 |
| EXD2 | KRTAP5-8 | 0.694752 | 3 | 0 | 3 |
| EXD2 | SLTM | 0.691567 | 3 | 0 | 3 |
| EXD2 | EPC1 | 0.69038 | 3 | 0 | 3 |
| EXD2 | ZNF837 | 0.685639 | 3 | 0 | 3 |
| EXD2 | CNOT1 | 0.684813 | 3 | 0 | 3 |
| EXD2 | USP25 | 0.683706 | 5 | 0 | 4 |
For details and further investigation, click here
