| Full name: C2 domain containing 3 centriole elongation regulator | Alias Symbol: DKFZP586P0123 | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 26005 | HGNC ID: HGNC:24564 | Ensembl Gene: ENSG00000168014 | OMIM ID: 615944 |
| Drug and gene relationship at DGIdb | |||
Expression of C2CD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C2CD3 | 26005 | 213199_at | 0.3676 | 0.5886 | |
| GSE20347 | C2CD3 | 26005 | 36552_at | 0.3643 | 0.0131 | |
| GSE23400 | C2CD3 | 26005 | 36552_at | 0.3038 | 0.0000 | |
| GSE26886 | C2CD3 | 26005 | 36552_at | 1.1634 | 0.0000 | |
| GSE29001 | C2CD3 | 26005 | 36552_at | 0.3736 | 0.1864 | |
| GSE38129 | C2CD3 | 26005 | 36552_at | 0.2713 | 0.0202 | |
| GSE45670 | C2CD3 | 26005 | 213199_at | 0.4024 | 0.0428 | |
| GSE53622 | C2CD3 | 26005 | 67007 | 0.6048 | 0.0000 | |
| GSE53624 | C2CD3 | 26005 | 40707 | -1.2874 | 0.0000 | |
| GSE63941 | C2CD3 | 26005 | 36552_at | 0.1779 | 0.8228 | |
| GSE77861 | C2CD3 | 26005 | 36552_at | 0.3102 | 0.1478 | |
| GSE97050 | C2CD3 | 26005 | A_23_P150741 | -0.4572 | 0.2873 | |
| SRP007169 | C2CD3 | 26005 | RNAseq | 1.7774 | 0.0001 | |
| SRP008496 | C2CD3 | 26005 | RNAseq | 2.3064 | 0.0000 | |
| SRP064894 | C2CD3 | 26005 | RNAseq | 0.5515 | 0.0090 | |
| SRP133303 | C2CD3 | 26005 | RNAseq | 0.3078 | 0.1595 | |
| SRP159526 | C2CD3 | 26005 | RNAseq | -0.1652 | 0.3740 | |
| SRP193095 | C2CD3 | 26005 | RNAseq | 0.4619 | 0.0020 | |
| SRP219564 | C2CD3 | 26005 | RNAseq | 0.4552 | 0.2495 | |
| TCGA | C2CD3 | 26005 | RNAseq | 0.0553 | 0.3977 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by C2CD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C2CD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C2CD3 | 26005 | 5 | 9 | 16 | |
| GSE20123 | C2CD3 | 26005 | 5 | 8 | 17 | |
| GSE43470 | C2CD3 | 26005 | 6 | 4 | 33 | |
| GSE46452 | C2CD3 | 26005 | 9 | 20 | 30 | |
| GSE47630 | C2CD3 | 26005 | 6 | 14 | 20 | |
| GSE54993 | C2CD3 | 26005 | 8 | 3 | 59 | |
| GSE54994 | C2CD3 | 26005 | 8 | 15 | 30 | |
| GSE60625 | C2CD3 | 26005 | 0 | 7 | 4 | |
| GSE74703 | C2CD3 | 26005 | 5 | 3 | 28 | |
| GSE74704 | C2CD3 | 26005 | 3 | 4 | 13 | |
| TCGA | C2CD3 | 26005 | 26 | 29 | 41 |
Total number of gains: 81; Total number of losses: 116; Total Number of normals: 291.
Somatic mutations of C2CD3:
Generating mutation plots.
Highly correlated genes for C2CD3:
Showing top 20/81 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C2CD3 | SCYL1 | 0.718793 | 3 | 0 | 3 |
| C2CD3 | LURAP1L | 0.709177 | 3 | 0 | 3 |
| C2CD3 | ALKBH6 | 0.708207 | 3 | 0 | 3 |
| C2CD3 | NEU3 | 0.707697 | 6 | 0 | 6 |
| C2CD3 | TENM4 | 0.704211 | 5 | 0 | 4 |
| C2CD3 | INTS4 | 0.678004 | 6 | 0 | 5 |
| C2CD3 | PPME1 | 0.672376 | 6 | 0 | 5 |
| C2CD3 | SPCS2 | 0.651388 | 8 | 0 | 7 |
| C2CD3 | MCOLN3 | 0.636317 | 4 | 0 | 3 |
| C2CD3 | MARK1 | 0.634555 | 5 | 0 | 5 |
| C2CD3 | ITPK1-AS1 | 0.62934 | 3 | 0 | 3 |
| C2CD3 | TTC30A | 0.627576 | 4 | 0 | 4 |
| C2CD3 | SFT2D3 | 0.62591 | 3 | 0 | 3 |
| C2CD3 | CEP95 | 0.623848 | 3 | 0 | 3 |
| C2CD3 | IRF2BP2 | 0.6225 | 3 | 0 | 3 |
| C2CD3 | AGAP2-AS1 | 0.615846 | 3 | 0 | 3 |
| C2CD3 | SULT1A1 | 0.614411 | 4 | 0 | 3 |
| C2CD3 | COA4 | 0.604982 | 9 | 0 | 6 |
| C2CD3 | TTF1 | 0.603345 | 7 | 0 | 6 |
| C2CD3 | RSF1 | 0.602824 | 9 | 0 | 9 |
For details and further investigation, click here
