COA4

 

Full name: cytochrome c oxidase assembly factor 4 homolog Alias Symbol: E2IG2|CMC3
Type: protein-coding gene Cytoband: 11q13.4
Entrez ID: 51287 HGNC ID: HGNC:24604 Ensembl Gene: ENSG00000181924 OMIM ID: 608016

 

Expression of COA4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 COA4 51287 220647_s_at 0.2699 0.7262
GSE20347 COA4 51287 220647_s_at 0.2540 0.1696
GSE23400 COA4 51287 220647_s_at 0.3961 0.0001
GSE26886 COA4 51287 220647_s_at 0.8497 0.0000
GSE29001 COA4 51287 220647_s_at 0.0950 0.7862
GSE38129 COA4 51287 220647_s_at 0.2935 0.0165
GSE45670 COA4 51287 220647_s_at 0.3413 0.0800
GSE53622 COA4 51287 96651 0.0281 0.7886
GSE53624 COA4 51287 96651 0.2739 0.0013
GSE63941 COA4 51287 220647_s_at 0.3953 0.3939
GSE77861 COA4 51287 220647_s_at 0.0650 0.8394
SRP007169 COA4 51287 RNAseq -0.0868 0.8583
SRP008496 COA4 51287 RNAseq 0.4511 0.1444
SRP064894 COA4 51287 RNAseq 0.4035 0.1118
SRP133303 COA4 51287 RNAseq 0.2191 0.4442
SRP159526 COA4 51287 RNAseq -0.0997 0.7732
SRP193095 COA4 51287 RNAseq 0.1282 0.5685
SRP219564 COA4 51287 RNAseq 0.3489 0.3847

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by COA4 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of COA4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 COA4 51287 5 9 16
GSE20123 COA4 51287 5 8 17
GSE43470 COA4 51287 6 4 33
GSE46452 COA4 51287 9 20 30
GSE47630 COA4 51287 6 14 20
GSE54993 COA4 51287 8 3 59
GSE54994 COA4 51287 8 15 30
GSE60625 COA4 51287 0 7 4
GSE74703 COA4 51287 5 3 28
GSE74704 COA4 51287 3 4 13
TCGA COA4 51287 28 27 41

Total number of gains: 83; Total number of losses: 114; Total Number of normals: 291.  

 

Somatic mutations of COA4:

 

Generating mutation plots.

 

Highly correlated genes for COA4:

 

Showing top 20/99 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
COA4MRPL480.79972211011
COA4INTS40.70646505
COA4CNTN50.695533303
COA4MMP130.692809303
COA4C14orf1190.672979303
COA4YAP10.669215303
COA4CLNS1A0.665317908
COA4SPCS20.6492311009
COA4PPME10.635504807
COA4PAAF10.6288341007
COA4CEP720.61687303
COA4NARS20.616174806
COA4MRPL140.613651404
COA4ALG80.609907
COA4C2CD30.604982906
COA4PTPN20.604601503
COA4TUBD10.603067303
COA4LRR10.595272403
COA4C15orf610.594551403
COA4CLPB0.591129906

For details and further investigation, click here