| Full name: chromosome 3 open reading frame 52 | Alias Symbol: FLJ23186|TTMP | ||
| Type: protein-coding gene | Cytoband: 3q13.2 | ||
| Entrez ID: 79669 | HGNC ID: HGNC:26255 | Ensembl Gene: ENSG00000114529 | OMIM ID: 611956 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of C3orf52:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C3orf52 | 79669 | 219474_at | 1.2181 | 0.0486 | |
| GSE20347 | C3orf52 | 79669 | 219474_at | 0.7333 | 0.0063 | |
| GSE23400 | C3orf52 | 79669 | 219474_at | 0.4343 | 0.0000 | |
| GSE26886 | C3orf52 | 79669 | 219474_at | 0.9772 | 0.0017 | |
| GSE29001 | C3orf52 | 79669 | 219474_at | 0.8538 | 0.0537 | |
| GSE38129 | C3orf52 | 79669 | 219474_at | 1.1025 | 0.0000 | |
| GSE45670 | C3orf52 | 79669 | 219474_at | 1.2512 | 0.0001 | |
| GSE53622 | C3orf52 | 79669 | 31608 | 0.6682 | 0.0000 | |
| GSE53624 | C3orf52 | 79669 | 31608 | 0.9014 | 0.0000 | |
| GSE63941 | C3orf52 | 79669 | 219474_at | 1.0458 | 0.1103 | |
| GSE77861 | C3orf52 | 79669 | 219474_at | 0.3500 | 0.1379 | |
| GSE97050 | C3orf52 | 79669 | A_23_P58009 | 0.3574 | 0.3382 | |
| SRP007169 | C3orf52 | 79669 | RNAseq | 0.7658 | 0.1004 | |
| SRP008496 | C3orf52 | 79669 | RNAseq | 1.2455 | 0.0011 | |
| SRP064894 | C3orf52 | 79669 | RNAseq | 0.9578 | 0.0049 | |
| SRP133303 | C3orf52 | 79669 | RNAseq | 0.9892 | 0.0001 | |
| SRP159526 | C3orf52 | 79669 | RNAseq | 0.5097 | 0.3254 | |
| SRP193095 | C3orf52 | 79669 | RNAseq | 0.5696 | 0.0324 | |
| SRP219564 | C3orf52 | 79669 | RNAseq | 1.0843 | 0.1310 | |
| TCGA | C3orf52 | 79669 | RNAseq | -0.2894 | 0.0297 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by C3orf52 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C3orf52:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C3orf52 | 79669 | 17 | 1 | 12 | |
| GSE20123 | C3orf52 | 79669 | 17 | 1 | 12 | |
| GSE43470 | C3orf52 | 79669 | 20 | 1 | 22 | |
| GSE46452 | C3orf52 | 79669 | 12 | 6 | 41 | |
| GSE47630 | C3orf52 | 79669 | 16 | 6 | 18 | |
| GSE54993 | C3orf52 | 79669 | 2 | 5 | 63 | |
| GSE54994 | C3orf52 | 79669 | 29 | 4 | 20 | |
| GSE60625 | C3orf52 | 79669 | 0 | 6 | 5 | |
| GSE74703 | C3orf52 | 79669 | 16 | 1 | 19 | |
| GSE74704 | C3orf52 | 79669 | 13 | 1 | 6 | |
| TCGA | C3orf52 | 79669 | 52 | 6 | 38 |
Total number of gains: 194; Total number of losses: 38; Total Number of normals: 256.
Somatic mutations of C3orf52:
Generating mutation plots.
Highly correlated genes for C3orf52:
Showing top 20/613 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C3orf52 | FBXO45 | 0.700295 | 3 | 0 | 3 |
| C3orf52 | MIIP | 0.675348 | 3 | 0 | 3 |
| C3orf52 | CHTF18 | 0.673254 | 5 | 0 | 5 |
| C3orf52 | LINC00958 | 0.668033 | 3 | 0 | 3 |
| C3orf52 | C4orf46 | 0.662684 | 3 | 0 | 3 |
| C3orf52 | CMIP | 0.658202 | 4 | 0 | 4 |
| C3orf52 | TMC8 | 0.658026 | 3 | 0 | 3 |
| C3orf52 | CD276 | 0.648569 | 5 | 0 | 3 |
| C3orf52 | RNMT | 0.645917 | 3 | 0 | 3 |
| C3orf52 | TIMM10 | 0.644249 | 4 | 0 | 3 |
| C3orf52 | PCSK9 | 0.642116 | 5 | 0 | 4 |
| C3orf52 | ELF4 | 0.6412 | 9 | 0 | 8 |
| C3orf52 | CC2D1B | 0.636976 | 3 | 0 | 3 |
| C3orf52 | TMEM132A | 0.634942 | 6 | 0 | 5 |
| C3orf52 | SLC20A1 | 0.632414 | 8 | 0 | 7 |
| C3orf52 | STPG1 | 0.628314 | 5 | 0 | 3 |
| C3orf52 | MEX3D | 0.628278 | 5 | 0 | 3 |
| C3orf52 | MRPL14 | 0.622164 | 6 | 0 | 5 |
| C3orf52 | COL27A1 | 0.619606 | 6 | 0 | 4 |
| C3orf52 | ALG1 | 0.61951 | 4 | 0 | 3 |
For details and further investigation, click here
