TIMM10

 

Full name: translocase of inner mitochondrial membrane 10 Alias Symbol: TIM10|TIM10A|TIMM10A
Type: protein-coding gene Cytoband: 11q12.1
Entrez ID: 26519 HGNC ID: HGNC:11814 Ensembl Gene: ENSG00000134809 OMIM ID: 602251
Drug and gene relationship at DGIdb

 

Expression of TIMM10:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TIMM10 26519 1555764_s_at 0.2692 0.5536
GSE20347 TIMM10 26519 218408_at 0.3442 0.0356
GSE23400 TIMM10 26519 218408_at 0.3146 0.0000
GSE26886 TIMM10 26519 1555764_s_at 0.1267 0.6748
GSE29001 TIMM10 26519 218408_at 0.2456 0.2901
GSE38129 TIMM10 26519 218408_at 0.3832 0.0053
GSE45670 TIMM10 26519 1555764_s_at 0.2855 0.0355
GSE53622 TIMM10 26519 28227 0.3012 0.0001
GSE53624 TIMM10 26519 28227 0.4240 0.0000
GSE63941 TIMM10 26519 1555764_s_at 0.5281 0.2783
GSE77861 TIMM10 26519 1555764_s_at 0.2185 0.4686
GSE97050 TIMM10 26519 A_23_P64343 0.3130 0.2462
SRP007169 TIMM10 26519 RNAseq 0.6870 0.3865
SRP064894 TIMM10 26519 RNAseq 0.4937 0.0701
SRP133303 TIMM10 26519 RNAseq 0.3769 0.0060
SRP159526 TIMM10 26519 RNAseq 0.3965 0.0719
SRP193095 TIMM10 26519 RNAseq -0.0636 0.7004
SRP219564 TIMM10 26519 RNAseq -0.0185 0.9504
TCGA TIMM10 26519 RNAseq 0.1983 0.0078

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TIMM10 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TIMM10:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TIMM10 26519 2 3 25
GSE20123 TIMM10 26519 2 3 25
GSE43470 TIMM10 26519 1 5 37
GSE46452 TIMM10 26519 9 4 46
GSE47630 TIMM10 26519 3 8 29
GSE54993 TIMM10 26519 3 0 67
GSE54994 TIMM10 26519 5 6 42
GSE60625 TIMM10 26519 0 3 8
GSE74703 TIMM10 26519 1 3 32
GSE74704 TIMM10 26519 2 3 15
TCGA TIMM10 26519 14 10 72

Total number of gains: 42; Total number of losses: 48; Total Number of normals: 398.  

 

Somatic mutations of TIMM10:

 

Generating mutation plots.

 

Highly correlated genes for TIMM10:

 

Showing top 20/241 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TIMM10SF3A30.676104403
TIMM10TOE10.674027303
TIMM10C3orf520.644249403
TIMM10B3GNTL10.640337403
TIMM10LSM80.632606605
TIMM10TTC9C0.61566605
TIMM10DCTPP10.612731008
TIMM10CDK50.60167605
TIMM10LSM70.599241706
TIMM10RANBP10.5992051006
TIMM10MED190.59821504
TIMM10PRPF190.596018907
TIMM10MRPL510.594956504
TIMM10MRPL40.59487806
TIMM10ERCC6L0.593878907
TIMM10NR2C2AP0.59227403
TIMM10POP70.592021807
TIMM10COMMD20.589775403
TIMM10EDARADD0.586784403
TIMM10MND10.585898605

For details and further investigation, click here