| Full name: F-box protein 45 | Alias Symbol: Fbx45 | ||
| Type: protein-coding gene | Cytoband: 3q29 | ||
| Entrez ID: 200933 | HGNC ID: HGNC:29148 | Ensembl Gene: ENSG00000174013 | OMIM ID: 609112 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO45:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO45 | 200933 | 225099_at | 1.1285 | 0.0496 | |
| GSE26886 | FBXO45 | 200933 | 225099_at | -0.1994 | 0.3890 | |
| GSE45670 | FBXO45 | 200933 | 225099_at | 0.7452 | 0.0035 | |
| GSE63941 | FBXO45 | 200933 | 225099_at | 0.3764 | 0.4936 | |
| GSE77861 | FBXO45 | 200933 | 225099_at | 0.6813 | 0.0624 | |
| SRP007169 | FBXO45 | 200933 | RNAseq | 1.6631 | 0.0025 | |
| SRP008496 | FBXO45 | 200933 | RNAseq | 1.9021 | 0.0000 | |
| SRP064894 | FBXO45 | 200933 | RNAseq | 0.5601 | 0.0191 | |
| SRP133303 | FBXO45 | 200933 | RNAseq | 1.1472 | 0.0000 | |
| SRP159526 | FBXO45 | 200933 | RNAseq | 1.2569 | 0.0001 | |
| SRP193095 | FBXO45 | 200933 | RNAseq | 0.6479 | 0.0000 | |
| SRP219564 | FBXO45 | 200933 | RNAseq | 0.2093 | 0.6167 | |
| TCGA | FBXO45 | 200933 | RNAseq | 0.3928 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by FBXO45 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FBXO45:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO45 | 200933 | 22 | 0 | 8 | |
| GSE20123 | FBXO45 | 200933 | 22 | 0 | 8 | |
| GSE43470 | FBXO45 | 200933 | 21 | 0 | 22 | |
| GSE46452 | FBXO45 | 200933 | 19 | 1 | 39 | |
| GSE47630 | FBXO45 | 200933 | 27 | 2 | 11 | |
| GSE54993 | FBXO45 | 200933 | 1 | 22 | 47 | |
| GSE54994 | FBXO45 | 200933 | 41 | 0 | 12 | |
| GSE60625 | FBXO45 | 200933 | 0 | 6 | 5 | |
| GSE74703 | FBXO45 | 200933 | 19 | 0 | 17 | |
| GSE74704 | FBXO45 | 200933 | 14 | 0 | 6 | |
| TCGA | FBXO45 | 200933 | 76 | 0 | 20 |
Total number of gains: 262; Total number of losses: 31; Total Number of normals: 195.
Somatic mutations of FBXO45:
Generating mutation plots.
Highly correlated genes for FBXO45:
Showing top 20/289 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO45 | LRRC58 | 0.792693 | 3 | 0 | 3 |
| FBXO45 | UMPS | 0.780116 | 3 | 0 | 3 |
| FBXO45 | WDR53 | 0.749032 | 5 | 0 | 5 |
| FBXO45 | TMEM185B | 0.743175 | 3 | 0 | 3 |
| FBXO45 | KPNA2 | 0.739378 | 3 | 0 | 3 |
| FBXO45 | UHRF1 | 0.737602 | 3 | 0 | 3 |
| FBXO45 | FUS | 0.735904 | 3 | 0 | 3 |
| FBXO45 | ABCA12 | 0.725183 | 3 | 0 | 3 |
| FBXO45 | NUDT1 | 0.721494 | 3 | 0 | 3 |
| FBXO45 | CKS1B | 0.720851 | 3 | 0 | 3 |
| FBXO45 | TIMMDC1 | 0.720261 | 3 | 0 | 3 |
| FBXO45 | OAZ1 | 0.718759 | 3 | 0 | 3 |
| FBXO45 | ABCF3 | 0.718613 | 4 | 0 | 4 |
| FBXO45 | SLC7A5 | 0.713645 | 3 | 0 | 3 |
| FBXO45 | MTFR2 | 0.711859 | 3 | 0 | 3 |
| FBXO45 | WDHD1 | 0.711846 | 3 | 0 | 3 |
| FBXO45 | FEN1 | 0.711076 | 3 | 0 | 3 |
| FBXO45 | LSG1 | 0.709376 | 4 | 0 | 4 |
| FBXO45 | POLE2 | 0.70851 | 3 | 0 | 3 |
| FBXO45 | MRPL47 | 0.70783 | 5 | 0 | 4 |
For details and further investigation, click here
