| Full name: chromosome 6 open reading frame 52 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p24.2 | ||
| Entrez ID: 347744 | HGNC ID: HGNC:20881 | Ensembl Gene: ENSG00000137434 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C6orf52:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C6orf52 | 347744 | 236504_x_at | 0.0948 | 0.8299 | |
| GSE26886 | C6orf52 | 347744 | 236504_x_at | 0.5091 | 0.0023 | |
| GSE45670 | C6orf52 | 347744 | 239417_x_at | 0.0336 | 0.8675 | |
| GSE53622 | C6orf52 | 347744 | 17549 | -0.0319 | 0.8405 | |
| GSE53624 | C6orf52 | 347744 | 105808 | 0.3581 | 0.0070 | |
| GSE63941 | C6orf52 | 347744 | 236504_x_at | 0.8097 | 0.0048 | |
| GSE77861 | C6orf52 | 347744 | 239417_x_at | -0.1257 | 0.5591 | |
| SRP159526 | C6orf52 | 347744 | RNAseq | 1.1375 | 0.0485 | |
| TCGA | C6orf52 | 347744 | RNAseq | 0.0281 | 0.9545 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by C6orf52 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C6orf52:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C6orf52 | 347744 | 4 | 7 | 19 | |
| GSE20123 | C6orf52 | 347744 | 4 | 7 | 19 | |
| GSE43470 | C6orf52 | 347744 | 8 | 2 | 33 | |
| GSE46452 | C6orf52 | 347744 | 1 | 10 | 48 | |
| GSE47630 | C6orf52 | 347744 | 7 | 8 | 25 | |
| GSE54993 | C6orf52 | 347744 | 1 | 1 | 68 | |
| GSE54994 | C6orf52 | 347744 | 10 | 3 | 40 | |
| GSE60625 | C6orf52 | 347744 | 0 | 1 | 10 | |
| GSE74703 | C6orf52 | 347744 | 7 | 2 | 27 | |
| GSE74704 | C6orf52 | 347744 | 2 | 3 | 15 | |
| TCGA | C6orf52 | 347744 | 15 | 28 | 53 |
Total number of gains: 59; Total number of losses: 72; Total Number of normals: 357.
Somatic mutations of C6orf52:
Generating mutation plots.
Highly correlated genes for C6orf52:
Showing top 20/39 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C6orf52 | MRPL4 | 0.701663 | 3 | 0 | 3 |
| C6orf52 | RPS19BP1 | 0.678798 | 3 | 0 | 3 |
| C6orf52 | ERI3 | 0.673145 | 3 | 0 | 3 |
| C6orf52 | PDAP1 | 0.652023 | 3 | 0 | 3 |
| C6orf52 | COX6A1 | 0.646103 | 4 | 0 | 4 |
| C6orf52 | WRAP73 | 0.641197 | 3 | 0 | 3 |
| C6orf52 | ACTR3B | 0.640652 | 3 | 0 | 3 |
| C6orf52 | SUV39H2 | 0.63487 | 3 | 0 | 3 |
| C6orf52 | LSM4 | 0.625194 | 3 | 0 | 3 |
| C6orf52 | RHEBL1 | 0.62363 | 3 | 0 | 3 |
| C6orf52 | PRR14 | 0.623381 | 3 | 0 | 3 |
| C6orf52 | PAGR1 | 0.620232 | 3 | 0 | 3 |
| C6orf52 | CRYBB3 | 0.615387 | 4 | 0 | 3 |
| C6orf52 | KLHL11 | 0.612119 | 3 | 0 | 3 |
| C6orf52 | NABP2 | 0.607305 | 4 | 0 | 3 |
| C6orf52 | PHB2 | 0.601384 | 4 | 0 | 3 |
| C6orf52 | MAD2L2 | 0.594176 | 4 | 0 | 3 |
| C6orf52 | NDUFA9 | 0.593222 | 4 | 0 | 3 |
| C6orf52 | LSM7 | 0.590774 | 4 | 0 | 3 |
| C6orf52 | TTLL4 | 0.586281 | 3 | 0 | 3 |
For details and further investigation, click here
