C8orf48

 

Full name: chromosome 8 open reading frame 48 Alias Symbol: FLJ25402
Type: protein-coding gene Cytoband: 8p22
Entrez ID: 157773 HGNC ID: HGNC:26345 Ensembl Gene: ENSG00000164743 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of C8orf48:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C8orf48 157773 236634_at -0.4204 0.3592
GSE26886 C8orf48 157773 236634_at 0.0023 0.9954
GSE45670 C8orf48 157773 236634_at -0.9479 0.0000
GSE53622 C8orf48 157773 72999 -0.7306 0.0001
GSE53624 C8orf48 157773 72999 -0.8902 0.0000
GSE63941 C8orf48 157773 236634_at -2.8212 0.0005
GSE77861 C8orf48 157773 236634_at -0.3513 0.0129
SRP133303 C8orf48 157773 RNAseq -0.2944 0.5882
SRP219564 C8orf48 157773 RNAseq -0.2664 0.5753
TCGA C8orf48 157773 RNAseq -0.4906 0.1675

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by C8orf48 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of C8orf48:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C8orf48 157773 4 11 15
GSE20123 C8orf48 157773 4 11 15
GSE43470 C8orf48 157773 4 9 30
GSE46452 C8orf48 157773 12 14 33
GSE47630 C8orf48 157773 9 8 23
GSE54993 C8orf48 157773 3 14 53
GSE54994 C8orf48 157773 8 18 27
GSE60625 C8orf48 157773 3 0 8
GSE74703 C8orf48 157773 4 7 25
GSE74704 C8orf48 157773 3 7 10
TCGA C8orf48 157773 13 41 42

Total number of gains: 67; Total number of losses: 140; Total Number of normals: 281.  


 

Somatic mutations of C8orf48:

 

Generating mutation plots.

 

Highly correlated genes for C8orf48:

 

Showing top 20/447 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C8orf48ZNF6260.749251303
C8orf48SUMF10.727091303
C8orf48RAET1E0.722499303
C8orf48DNTT0.722201303
C8orf48SFTA20.715961303
C8orf48SNORA680.707338303
C8orf48GYPC0.702907403
C8orf48ATG9B0.694479303
C8orf48SGMS20.679149303
C8orf48SPNS20.674831303
C8orf48SESN10.673917303
C8orf48ZFPM20.671716303
C8orf48TTC90.667722303
C8orf48SLC44A30.6677303
C8orf48CRYBG30.667073404
C8orf48IL12A0.666851504
C8orf48SECISBP2L0.662447504
C8orf48RINT10.659208303
C8orf48SLC30A90.658201404
C8orf48ENTPD50.657768404

For details and further investigation, click here