| Full name: LIM and cysteine rich domains 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p25.3 | ||
| Entrez ID: 29995 | HGNC ID: HGNC:6633 | Ensembl Gene: ENSG00000071282 | OMIM ID: 604859 |
| Drug and gene relationship at DGIdb | |||
Expression of LMCD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LMCD1 | 29995 | 218574_s_at | -0.2864 | 0.6817 | |
| GSE20347 | LMCD1 | 29995 | 218574_s_at | -0.0502 | 0.8317 | |
| GSE23400 | LMCD1 | 29995 | 218574_s_at | 0.2794 | 0.0024 | |
| GSE26886 | LMCD1 | 29995 | 218574_s_at | -0.5337 | 0.1643 | |
| GSE29001 | LMCD1 | 29995 | 218574_s_at | -0.1393 | 0.6431 | |
| GSE38129 | LMCD1 | 29995 | 218574_s_at | 0.0192 | 0.9369 | |
| GSE45670 | LMCD1 | 29995 | 218574_s_at | -1.2090 | 0.0000 | |
| GSE53622 | LMCD1 | 29995 | 47883 | -0.2601 | 0.0360 | |
| GSE53624 | LMCD1 | 29995 | 47883 | -0.0033 | 0.9777 | |
| GSE63941 | LMCD1 | 29995 | 218574_s_at | -2.3071 | 0.0393 | |
| GSE77861 | LMCD1 | 29995 | 218574_s_at | -0.0351 | 0.9027 | |
| GSE97050 | LMCD1 | 29995 | A_23_P6771 | 0.2167 | 0.6544 | |
| SRP007169 | LMCD1 | 29995 | RNAseq | 1.4988 | 0.0038 | |
| SRP008496 | LMCD1 | 29995 | RNAseq | 1.4906 | 0.0000 | |
| SRP064894 | LMCD1 | 29995 | RNAseq | 0.3924 | 0.3363 | |
| SRP133303 | LMCD1 | 29995 | RNAseq | -0.2921 | 0.1126 | |
| SRP159526 | LMCD1 | 29995 | RNAseq | 0.4394 | 0.4051 | |
| SRP193095 | LMCD1 | 29995 | RNAseq | 0.3018 | 0.1913 | |
| SRP219564 | LMCD1 | 29995 | RNAseq | -0.5537 | 0.4895 | |
| TCGA | LMCD1 | 29995 | RNAseq | -0.4250 | 0.0001 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by LMCD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LMCD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LMCD1 | 29995 | 1 | 18 | 11 | |
| GSE20123 | LMCD1 | 29995 | 1 | 18 | 11 | |
| GSE43470 | LMCD1 | 29995 | 0 | 20 | 23 | |
| GSE46452 | LMCD1 | 29995 | 2 | 17 | 40 | |
| GSE47630 | LMCD1 | 29995 | 1 | 23 | 16 | |
| GSE54993 | LMCD1 | 29995 | 6 | 1 | 63 | |
| GSE54994 | LMCD1 | 29995 | 2 | 32 | 19 | |
| GSE60625 | LMCD1 | 29995 | 5 | 0 | 6 | |
| GSE74703 | LMCD1 | 29995 | 0 | 17 | 19 | |
| GSE74704 | LMCD1 | 29995 | 1 | 11 | 8 | |
| TCGA | LMCD1 | 29995 | 3 | 66 | 27 |
Total number of gains: 22; Total number of losses: 223; Total Number of normals: 243.
Somatic mutations of LMCD1:
Generating mutation plots.
Highly correlated genes for LMCD1:
Showing top 20/376 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LMCD1 | GIMAP8 | 0.743497 | 3 | 0 | 3 |
| LMCD1 | C9orf72 | 0.742714 | 3 | 0 | 3 |
| LMCD1 | NHS | 0.720707 | 3 | 0 | 3 |
| LMCD1 | TNFRSF19 | 0.705155 | 4 | 0 | 4 |
| LMCD1 | ZNF570 | 0.696595 | 3 | 0 | 3 |
| LMCD1 | AHRR | 0.692008 | 3 | 0 | 3 |
| LMCD1 | EMCN | 0.683755 | 4 | 0 | 4 |
| LMCD1 | STX3 | 0.680461 | 3 | 0 | 3 |
| LMCD1 | CLCC1 | 0.679706 | 3 | 0 | 3 |
| LMCD1 | KDM3A | 0.673099 | 3 | 0 | 3 |
| LMCD1 | SOX17 | 0.662002 | 4 | 0 | 4 |
| LMCD1 | ANKRD34A | 0.660825 | 3 | 0 | 3 |
| LMCD1 | CLSTN2 | 0.658171 | 3 | 0 | 3 |
| LMCD1 | SPOCK1 | 0.656858 | 5 | 0 | 5 |
| LMCD1 | ARL2BP | 0.653692 | 4 | 0 | 3 |
| LMCD1 | ZNF407 | 0.649946 | 3 | 0 | 3 |
| LMCD1 | CABLES1 | 0.646671 | 4 | 0 | 4 |
| LMCD1 | ERLIN2 | 0.641778 | 3 | 0 | 3 |
| LMCD1 | LRRK2 | 0.638616 | 4 | 0 | 4 |
| LMCD1 | SLITRK3 | 0.63765 | 3 | 0 | 3 |
For details and further investigation, click here
