| Full name: calreticulin 3 | Alias Symbol: CRT2|FLJ25355|MGC26577|CT93 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 125972 | HGNC ID: HGNC:20407 | Ensembl Gene: ENSG00000269058 | OMIM ID: 611414 |
| Drug and gene relationship at DGIdb | |||
Expression of CALR3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CALR3 | 125972 | 1552421_a_at | -0.2871 | 0.1748 | |
| GSE26886 | CALR3 | 125972 | 1552421_a_at | -0.1034 | 0.3316 | |
| GSE45670 | CALR3 | 125972 | 1552421_a_at | -0.0171 | 0.8657 | |
| GSE63941 | CALR3 | 125972 | 1552421_a_at | 0.1483 | 0.2146 | |
| GSE77861 | CALR3 | 125972 | 1552421_a_at | -0.1516 | 0.2324 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CALR3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CALR3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CALR3 | 125972 | 4 | 3 | 23 | |
| GSE20123 | CALR3 | 125972 | 3 | 2 | 25 | |
| GSE43470 | CALR3 | 125972 | 2 | 6 | 35 | |
| GSE46452 | CALR3 | 125972 | 47 | 1 | 11 | |
| GSE47630 | CALR3 | 125972 | 4 | 8 | 28 | |
| GSE54993 | CALR3 | 125972 | 15 | 4 | 51 | |
| GSE54994 | CALR3 | 125972 | 6 | 14 | 33 | |
| GSE60625 | CALR3 | 125972 | 9 | 0 | 2 | |
| GSE74703 | CALR3 | 125972 | 2 | 4 | 30 | |
| GSE74704 | CALR3 | 125972 | 0 | 1 | 19 | |
| TCGA | CALR3 | 125972 | 17 | 10 | 69 |
Total number of gains: 109; Total number of losses: 53; Total Number of normals: 326.
Somatic mutations of CALR3:
Generating mutation plots.
Highly correlated genes for CALR3:
Showing top 20/38 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CALR3 | TMPRSS11E | 0.715868 | 3 | 0 | 3 |
| CALR3 | ZBTB46-AS1 | 0.702343 | 3 | 0 | 3 |
| CALR3 | SH3RF2 | 0.687651 | 3 | 0 | 3 |
| CALR3 | CARS-AS1 | 0.655279 | 4 | 0 | 3 |
| CALR3 | SCEL | 0.652877 | 3 | 0 | 3 |
| CALR3 | PIAS1 | 0.637226 | 4 | 0 | 3 |
| CALR3 | SLC44A2 | 0.607141 | 3 | 0 | 3 |
| CALR3 | CCDC57 | 0.600772 | 3 | 0 | 3 |
| CALR3 | RPS6KA2-AS1 | 0.600471 | 4 | 0 | 3 |
| CALR3 | IQCD | 0.597458 | 4 | 0 | 3 |
| CALR3 | CRB3 | 0.592255 | 4 | 0 | 3 |
| CALR3 | NR5A1 | 0.591076 | 3 | 0 | 3 |
| CALR3 | HAAO | 0.587357 | 4 | 0 | 3 |
| CALR3 | CAPN11 | 0.570282 | 4 | 0 | 3 |
| CALR3 | ATG13 | 0.568652 | 4 | 0 | 3 |
| CALR3 | MAPK8IP1 | 0.565261 | 4 | 0 | 3 |
| CALR3 | S100A9 | 0.562845 | 3 | 0 | 3 |
| CALR3 | INSL6 | 0.562582 | 3 | 0 | 3 |
| CALR3 | MAL | 0.560123 | 3 | 0 | 3 |
| CALR3 | SULT2B1 | 0.559842 | 4 | 0 | 3 |
For details and further investigation, click here
