| Full name: insulin like 6 | Alias Symbol: RIF1 | ||
| Type: protein-coding gene | Cytoband: 9p24.1 | ||
| Entrez ID: 11172 | HGNC ID: HGNC:6089 | Ensembl Gene: ENSG00000120210 | OMIM ID: 606414 |
| Drug and gene relationship at DGIdb | |||
Expression of INSL6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | INSL6 | 11172 | 221403_s_at | -0.1436 | 0.6909 | |
| GSE20347 | INSL6 | 11172 | 221403_s_at | -0.0937 | 0.1842 | |
| GSE23400 | INSL6 | 11172 | 221403_s_at | -0.1370 | 0.0008 | |
| GSE26886 | INSL6 | 11172 | 221403_s_at | 0.0590 | 0.6771 | |
| GSE29001 | INSL6 | 11172 | 221403_s_at | -0.0472 | 0.7197 | |
| GSE38129 | INSL6 | 11172 | 221403_s_at | -0.1662 | 0.0113 | |
| GSE45670 | INSL6 | 11172 | 221403_s_at | 0.0854 | 0.3472 | |
| GSE53622 | INSL6 | 11172 | 94092 | -0.0802 | 0.4939 | |
| GSE53624 | INSL6 | 11172 | 94092 | -0.5238 | 0.0000 | |
| GSE63941 | INSL6 | 11172 | 221403_s_at | 0.0175 | 0.9300 | |
| GSE77861 | INSL6 | 11172 | 221403_s_at | -0.3088 | 0.0577 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by INSL6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of INSL6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | INSL6 | 11172 | 1 | 17 | 12 | |
| GSE20123 | INSL6 | 11172 | 1 | 16 | 13 | |
| GSE43470 | INSL6 | 11172 | 5 | 11 | 27 | |
| GSE46452 | INSL6 | 11172 | 2 | 23 | 34 | |
| GSE47630 | INSL6 | 11172 | 5 | 26 | 9 | |
| GSE54993 | INSL6 | 11172 | 6 | 3 | 61 | |
| GSE54994 | INSL6 | 11172 | 9 | 17 | 27 | |
| GSE60625 | INSL6 | 11172 | 0 | 2 | 9 | |
| GSE74703 | INSL6 | 11172 | 5 | 8 | 23 | |
| GSE74704 | INSL6 | 11172 | 0 | 12 | 8 | |
| TCGA | INSL6 | 11172 | 14 | 50 | 32 |
Total number of gains: 48; Total number of losses: 185; Total Number of normals: 255.
Somatic mutations of INSL6:
Generating mutation plots.
Highly correlated genes for INSL6:
Showing top 20/255 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| INSL6 | SSTR4 | 0.71302 | 4 | 0 | 4 |
| INSL6 | FGF17 | 0.658266 | 4 | 0 | 4 |
| INSL6 | ENTPD2 | 0.65549 | 3 | 0 | 3 |
| INSL6 | DPF3 | 0.652297 | 3 | 0 | 3 |
| INSL6 | MATN1 | 0.646614 | 5 | 0 | 4 |
| INSL6 | FOLH1 | 0.646502 | 4 | 0 | 4 |
| INSL6 | ONECUT1 | 0.644502 | 3 | 0 | 3 |
| INSL6 | SIT1 | 0.642921 | 3 | 0 | 3 |
| INSL6 | KCNG2 | 0.639754 | 3 | 0 | 3 |
| INSL6 | CCDC30 | 0.636176 | 3 | 0 | 3 |
| INSL6 | OR2B2 | 0.633969 | 3 | 0 | 3 |
| INSL6 | CDH15 | 0.633155 | 3 | 0 | 3 |
| INSL6 | IL25 | 0.632328 | 3 | 0 | 3 |
| INSL6 | RBFADN | 0.63231 | 3 | 0 | 3 |
| INSL6 | KCNK15 | 0.62984 | 3 | 0 | 3 |
| INSL6 | CAPN11 | 0.628528 | 4 | 0 | 4 |
| INSL6 | NXF5 | 0.626837 | 4 | 0 | 3 |
| INSL6 | FGA | 0.6237 | 3 | 0 | 3 |
| INSL6 | RBMXL2 | 0.622262 | 3 | 0 | 3 |
| INSL6 | ADAM7 | 0.618487 | 4 | 0 | 3 |
For details and further investigation, click here
