| Full name: mucin 21, cell surface associated | Alias Symbol: bCX31G15.2 | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 394263 | HGNC ID: HGNC:21661 | Ensembl Gene: ENSG00000204544 | OMIM ID: 616991 |
| Drug and gene relationship at DGIdb | |||
Expression of MUC21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | MUC21 | 394263 | 78100 | -3.7865 | 0.0000 | |
| GSE53624 | MUC21 | 394263 | 29027 | -4.1660 | 0.0000 | |
| SRP007169 | MUC21 | 394263 | RNAseq | -14.1403 | 0.0000 | |
| SRP008496 | MUC21 | 394263 | RNAseq | -4.6406 | 0.0195 | |
| SRP064894 | MUC21 | 394263 | RNAseq | -5.1118 | 0.0000 | |
| SRP133303 | MUC21 | 394263 | RNAseq | -7.3330 | 0.0000 | |
| SRP159526 | MUC21 | 394263 | RNAseq | -7.9075 | 0.0000 | |
| SRP219564 | MUC21 | 394263 | RNAseq | -5.5289 | 0.0003 | |
| TCGA | MUC21 | 394263 | RNAseq | -0.7967 | 0.2837 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by MUC21 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MUC21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MUC21 | 394263 | 5 | 1 | 24 | |
| GSE20123 | MUC21 | 394263 | 5 | 1 | 24 | |
| GSE43470 | MUC21 | 394263 | 5 | 1 | 37 | |
| GSE46452 | MUC21 | 394263 | 1 | 10 | 48 | |
| GSE47630 | MUC21 | 394263 | 7 | 3 | 30 | |
| GSE54993 | MUC21 | 394263 | 2 | 1 | 67 | |
| GSE54994 | MUC21 | 394263 | 11 | 4 | 38 | |
| GSE60625 | MUC21 | 394263 | 0 | 1 | 10 | |
| GSE74703 | MUC21 | 394263 | 5 | 0 | 31 | |
| GSE74704 | MUC21 | 394263 | 2 | 0 | 18 | |
| TCGA | MUC21 | 394263 | 17 | 16 | 63 |
Total number of gains: 60; Total number of losses: 38; Total Number of normals: 390.
Somatic mutations of MUC21:
Generating mutation plots.
Highly correlated genes for MUC21:
Showing top 20/50 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MUC21 | TMPRSS11B | 0.909183 | 3 | 0 | 3 |
| MUC21 | CRNN | 0.897517 | 3 | 0 | 3 |
| MUC21 | CAPN14 | 0.891594 | 3 | 0 | 3 |
| MUC21 | PRSS27 | 0.887804 | 3 | 0 | 3 |
| MUC21 | SPINK5 | 0.873204 | 3 | 0 | 3 |
| MUC21 | SLURP1 | 0.864246 | 3 | 0 | 3 |
| MUC21 | LYPD2 | 0.86196 | 3 | 0 | 3 |
| MUC21 | KRT4 | 0.857735 | 3 | 0 | 3 |
| MUC21 | HCG22 | 0.856941 | 3 | 0 | 3 |
| MUC21 | CLCA4 | 0.847461 | 3 | 0 | 3 |
| MUC21 | SCEL | 0.845926 | 3 | 0 | 3 |
| MUC21 | MAL | 0.840439 | 3 | 0 | 3 |
| MUC21 | KRT78 | 0.832966 | 3 | 0 | 3 |
| MUC21 | LYNX1 | 0.828157 | 3 | 0 | 3 |
| MUC21 | NCCRP1 | 0.827528 | 3 | 0 | 3 |
| MUC21 | SPINK7 | 0.823349 | 3 | 0 | 3 |
| MUC21 | A2ML1 | 0.822026 | 3 | 0 | 3 |
| MUC21 | TGM3 | 0.809322 | 3 | 0 | 3 |
| MUC21 | KLK13 | 0.802979 | 3 | 0 | 3 |
| MUC21 | FAM3D | 0.787462 | 3 | 0 | 3 |
For details and further investigation, click here
