| Full name: caspase 14 | Alias Symbol: MICE|MGC119078|MGC119079 | ||
| Type: protein-coding gene | Cytoband: 19p13.12 | ||
| Entrez ID: 23581 | HGNC ID: HGNC:1502 | Ensembl Gene: ENSG00000105141 | OMIM ID: 605848 |
| Drug and gene relationship at DGIdb | |||
Expression of CASP14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CASP14 | 23581 | 231722_at | 0.6386 | 0.2311 | |
| GSE26886 | CASP14 | 23581 | 231722_at | -0.0448 | 0.7571 | |
| GSE45670 | CASP14 | 23581 | 231722_at | 0.0962 | 0.4023 | |
| GSE53622 | CASP14 | 23581 | 108096 | 1.4670 | 0.0000 | |
| GSE53624 | CASP14 | 23581 | 108096 | 0.7902 | 0.0000 | |
| GSE63941 | CASP14 | 23581 | 231722_at | 0.2392 | 0.3116 | |
| GSE77861 | CASP14 | 23581 | 231722_at | -0.1387 | 0.1764 | |
| GSE97050 | CASP14 | 23581 | A_23_P90407 | 1.7438 | 0.1991 | |
| SRP133303 | CASP14 | 23581 | RNAseq | 1.1096 | 0.0188 | |
| SRP159526 | CASP14 | 23581 | RNAseq | 0.7966 | 0.1497 | |
| SRP193095 | CASP14 | 23581 | RNAseq | 0.1597 | 0.4680 | |
| TCGA | CASP14 | 23581 | RNAseq | 3.0565 | 0.0020 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by CASP14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CASP14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CASP14 | 23581 | 4 | 2 | 24 | |
| GSE20123 | CASP14 | 23581 | 3 | 1 | 26 | |
| GSE43470 | CASP14 | 23581 | 2 | 6 | 35 | |
| GSE46452 | CASP14 | 23581 | 47 | 1 | 11 | |
| GSE47630 | CASP14 | 23581 | 4 | 7 | 29 | |
| GSE54993 | CASP14 | 23581 | 15 | 4 | 51 | |
| GSE54994 | CASP14 | 23581 | 6 | 13 | 34 | |
| GSE60625 | CASP14 | 23581 | 9 | 0 | 2 | |
| GSE74703 | CASP14 | 23581 | 2 | 4 | 30 | |
| GSE74704 | CASP14 | 23581 | 0 | 1 | 19 | |
| TCGA | CASP14 | 23581 | 20 | 10 | 66 |
Total number of gains: 112; Total number of losses: 49; Total Number of normals: 327.
Somatic mutations of CASP14:
Generating mutation plots.
Highly correlated genes for CASP14:
Showing top 20/24 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CASP14 | SYNGR4 | 0.788806 | 3 | 0 | 3 |
| CASP14 | COL2A1 | 0.682923 | 3 | 0 | 3 |
| CASP14 | FCAMR | 0.672646 | 3 | 0 | 3 |
| CASP14 | CEACAM19 | 0.652124 | 5 | 0 | 4 |
| CASP14 | WFDC5 | 0.633396 | 4 | 0 | 3 |
| CASP14 | FANCA | 0.632909 | 3 | 0 | 3 |
| CASP14 | CCL20 | 0.621265 | 4 | 0 | 4 |
| CASP14 | DNAH2 | 0.619726 | 3 | 0 | 3 |
| CASP14 | POLR3G | 0.590435 | 4 | 0 | 3 |
| CASP14 | FBXO2 | 0.588704 | 3 | 0 | 3 |
| CASP14 | CA2 | 0.58317 | 4 | 0 | 3 |
| CASP14 | CA9 | 0.581425 | 6 | 0 | 4 |
| CASP14 | PDZK1IP1 | 0.580052 | 5 | 0 | 3 |
| CASP14 | GPRIN1 | 0.579747 | 4 | 0 | 3 |
| CASP14 | TMEM239 | 0.574937 | 3 | 0 | 3 |
| CASP14 | EPHB2 | 0.569954 | 5 | 0 | 3 |
| CASP14 | RDH16 | 0.560168 | 4 | 0 | 3 |
| CASP14 | ZFHX2 | 0.557591 | 4 | 0 | 3 |
| CASP14 | WNT10A | 0.556878 | 4 | 0 | 3 |
| CASP14 | S100A7A | 0.540835 | 5 | 0 | 3 |
For details and further investigation, click here
