| Full name: WAP four-disulfide core domain 5 | Alias Symbol: WAP1|dJ211D12.5 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 149708 | HGNC ID: HGNC:20477 | Ensembl Gene: ENSG00000175121 | OMIM ID: 605161 |
| Drug and gene relationship at DGIdb | |||
Expression of WFDC5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WFDC5 | 149708 | 242204_at | 1.1428 | 0.4034 | |
| GSE26886 | WFDC5 | 149708 | 242204_at | -0.0874 | 0.8244 | |
| GSE45670 | WFDC5 | 149708 | 242204_at | 1.5437 | 0.0006 | |
| GSE53622 | WFDC5 | 149708 | 145597 | 0.7413 | 0.0092 | |
| GSE53624 | WFDC5 | 149708 | 145597 | 0.3064 | 0.0655 | |
| GSE63941 | WFDC5 | 149708 | 242204_at | 0.3162 | 0.1311 | |
| GSE77861 | WFDC5 | 149708 | 242204_at | 0.4893 | 0.4053 | |
| GSE97050 | WFDC5 | 149708 | A_23_P402331 | 0.9405 | 0.1556 | |
| SRP064894 | WFDC5 | 149708 | RNAseq | 0.2172 | 0.6897 | |
| SRP133303 | WFDC5 | 149708 | RNAseq | 0.4602 | 0.2871 | |
| SRP159526 | WFDC5 | 149708 | RNAseq | 0.3529 | 0.7838 | |
| SRP219564 | WFDC5 | 149708 | RNAseq | -2.4820 | 0.0223 | |
| TCGA | WFDC5 | 149708 | RNAseq | 1.5659 | 0.0002 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by WFDC5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WFDC5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WFDC5 | 149708 | 13 | 1 | 16 | |
| GSE20123 | WFDC5 | 149708 | 13 | 1 | 16 | |
| GSE43470 | WFDC5 | 149708 | 12 | 1 | 30 | |
| GSE46452 | WFDC5 | 149708 | 29 | 0 | 30 | |
| GSE47630 | WFDC5 | 149708 | 24 | 1 | 15 | |
| GSE54993 | WFDC5 | 149708 | 0 | 17 | 53 | |
| GSE54994 | WFDC5 | 149708 | 25 | 0 | 28 | |
| GSE60625 | WFDC5 | 149708 | 0 | 0 | 11 | |
| GSE74703 | WFDC5 | 149708 | 10 | 1 | 25 | |
| GSE74704 | WFDC5 | 149708 | 9 | 0 | 11 | |
| TCGA | WFDC5 | 149708 | 45 | 3 | 48 |
Total number of gains: 180; Total number of losses: 25; Total Number of normals: 283.
Somatic mutations of WFDC5:
Generating mutation plots.
Highly correlated genes for WFDC5:
Showing top 20/185 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WFDC5 | GJA3 | 0.706522 | 4 | 0 | 4 |
| WFDC5 | ABCA12 | 0.684999 | 6 | 0 | 5 |
| WFDC5 | SQLE | 0.680095 | 4 | 0 | 4 |
| WFDC5 | LCE3D | 0.677849 | 6 | 0 | 6 |
| WFDC5 | ALOXE3 | 0.67619 | 7 | 0 | 6 |
| WFDC5 | SPRR4 | 0.672251 | 3 | 0 | 3 |
| WFDC5 | SLC5A1 | 0.669997 | 4 | 0 | 3 |
| WFDC5 | SPRR2G | 0.665263 | 8 | 0 | 6 |
| WFDC5 | MYO10 | 0.654236 | 3 | 0 | 3 |
| WFDC5 | PI3 | 0.653093 | 8 | 0 | 7 |
| WFDC5 | LCE3E | 0.650234 | 4 | 0 | 4 |
| WFDC5 | PLA2G4E | 0.650115 | 3 | 0 | 3 |
| WFDC5 | MTFP1 | 0.647862 | 3 | 0 | 3 |
| WFDC5 | S100A12 | 0.64628 | 5 | 0 | 4 |
| WFDC5 | IL36G | 0.645306 | 6 | 0 | 5 |
| WFDC5 | CPSF3 | 0.644983 | 3 | 0 | 3 |
| WFDC5 | PC | 0.643427 | 4 | 0 | 3 |
| WFDC5 | ARSI | 0.639868 | 4 | 0 | 3 |
| WFDC5 | CASP14 | 0.633396 | 4 | 0 | 3 |
| WFDC5 | CHST13 | 0.629669 | 3 | 0 | 3 |
For details and further investigation, click here
