| Full name: PDZK1 interacting protein 1 | Alias Symbol: DD96|MAP17|SPAP | ||
| Type: protein-coding gene | Cytoband: 1p33 | ||
| Entrez ID: 10158 | HGNC ID: HGNC:16887 | Ensembl Gene: ENSG00000162366 | OMIM ID: 607178 |
| Drug and gene relationship at DGIdb | |||
Expression of PDZK1IP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDZK1IP1 | 10158 | 219630_at | -0.4252 | 0.8818 | |
| GSE20347 | PDZK1IP1 | 10158 | 219630_at | -1.8603 | 0.0012 | |
| GSE23400 | PDZK1IP1 | 10158 | 219630_at | -1.4060 | 0.0000 | |
| GSE26886 | PDZK1IP1 | 10158 | 219630_at | -3.2887 | 0.0000 | |
| GSE29001 | PDZK1IP1 | 10158 | 219630_at | -1.7024 | 0.0020 | |
| GSE38129 | PDZK1IP1 | 10158 | 219630_at | -1.2798 | 0.0376 | |
| GSE45670 | PDZK1IP1 | 10158 | 219630_at | 1.7520 | 0.0000 | |
| GSE53622 | PDZK1IP1 | 10158 | 74126 | -0.9820 | 0.0003 | |
| GSE53624 | PDZK1IP1 | 10158 | 74126 | -1.6026 | 0.0000 | |
| GSE63941 | PDZK1IP1 | 10158 | 219630_at | 1.2731 | 0.4455 | |
| GSE77861 | PDZK1IP1 | 10158 | 219630_at | -0.7714 | 0.4152 | |
| GSE97050 | PDZK1IP1 | 10158 | A_33_P3393801 | 1.0959 | 0.2791 | |
| SRP007169 | PDZK1IP1 | 10158 | RNAseq | -4.6911 | 0.0057 | |
| SRP008496 | PDZK1IP1 | 10158 | RNAseq | -3.2928 | 0.0031 | |
| SRP064894 | PDZK1IP1 | 10158 | RNAseq | -0.5594 | 0.3197 | |
| SRP133303 | PDZK1IP1 | 10158 | RNAseq | -0.7182 | 0.1189 | |
| SRP159526 | PDZK1IP1 | 10158 | RNAseq | -2.2762 | 0.0016 | |
| SRP193095 | PDZK1IP1 | 10158 | RNAseq | -0.6576 | 0.0706 | |
| SRP219564 | PDZK1IP1 | 10158 | RNAseq | 0.0676 | 0.9658 | |
| TCGA | PDZK1IP1 | 10158 | RNAseq | 0.1465 | 0.5798 |
Upregulated datasets: 1; Downregulated datasets: 9.
Survival by PDZK1IP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDZK1IP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDZK1IP1 | 10158 | 4 | 3 | 23 | |
| GSE20123 | PDZK1IP1 | 10158 | 4 | 2 | 24 | |
| GSE43470 | PDZK1IP1 | 10158 | 5 | 1 | 37 | |
| GSE46452 | PDZK1IP1 | 10158 | 2 | 1 | 56 | |
| GSE47630 | PDZK1IP1 | 10158 | 8 | 4 | 28 | |
| GSE54993 | PDZK1IP1 | 10158 | 0 | 1 | 69 | |
| GSE54994 | PDZK1IP1 | 10158 | 11 | 2 | 40 | |
| GSE60625 | PDZK1IP1 | 10158 | 0 | 0 | 11 | |
| GSE74703 | PDZK1IP1 | 10158 | 4 | 1 | 31 | |
| GSE74704 | PDZK1IP1 | 10158 | 2 | 0 | 18 | |
| TCGA | PDZK1IP1 | 10158 | 10 | 17 | 69 |
Total number of gains: 50; Total number of losses: 32; Total Number of normals: 406.
Somatic mutations of PDZK1IP1:
Generating mutation plots.
Highly correlated genes for PDZK1IP1:
Showing top 20/789 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDZK1IP1 | LCN2 | 0.758705 | 12 | 0 | 12 |
| PDZK1IP1 | S100A9 | 0.736734 | 13 | 0 | 12 |
| PDZK1IP1 | SLPI | 0.717851 | 12 | 0 | 12 |
| PDZK1IP1 | IL20RB | 0.716971 | 7 | 0 | 7 |
| PDZK1IP1 | DUOX1 | 0.716283 | 9 | 0 | 9 |
| PDZK1IP1 | LYPD3 | 0.705553 | 11 | 0 | 11 |
| PDZK1IP1 | ATP10B | 0.703978 | 9 | 0 | 8 |
| PDZK1IP1 | TMPRSS11D | 0.702483 | 11 | 0 | 10 |
| PDZK1IP1 | ITGAD | 0.702277 | 3 | 0 | 3 |
| PDZK1IP1 | S100A12 | 0.701777 | 12 | 0 | 12 |
| PDZK1IP1 | SPRR2D | 0.700798 | 4 | 0 | 4 |
| PDZK1IP1 | PITX1 | 0.696673 | 8 | 0 | 8 |
| PDZK1IP1 | SPRR2A | 0.694666 | 4 | 0 | 4 |
| PDZK1IP1 | TMEM79 | 0.69466 | 7 | 0 | 7 |
| PDZK1IP1 | SDCBP2 | 0.691034 | 4 | 0 | 4 |
| PDZK1IP1 | KLK13 | 0.690108 | 10 | 0 | 10 |
| PDZK1IP1 | SPRR2E | 0.689368 | 4 | 0 | 4 |
| PDZK1IP1 | SERPINB4 | 0.687606 | 12 | 0 | 12 |
| PDZK1IP1 | SPRR2F | 0.683879 | 4 | 0 | 4 |
| PDZK1IP1 | NMU | 0.683729 | 8 | 0 | 8 |
For details and further investigation, click here
