| Full name: retinol dehydrogenase 16 | Alias Symbol: RODH-4|SDR9C8 | ||
| Type: protein-coding gene | Cytoband: 12q13.3 | ||
| Entrez ID: 8608 | HGNC ID: HGNC:29674 | Ensembl Gene: ENSG00000139547 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RDH16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RDH16 | 8608 | 206753_at | 0.7129 | 0.1072 | |
| GSE20347 | RDH16 | 8608 | 206753_at | 0.3415 | 0.0416 | |
| GSE23400 | RDH16 | 8608 | 206753_at | 0.0723 | 0.1707 | |
| GSE26886 | RDH16 | 8608 | 206753_at | -0.2484 | 0.5397 | |
| GSE29001 | RDH16 | 8608 | 206753_at | 0.4573 | 0.3398 | |
| GSE38129 | RDH16 | 8608 | 206753_at | 0.3183 | 0.0741 | |
| GSE45670 | RDH16 | 8608 | 206753_at | 0.7901 | 0.0015 | |
| GSE53622 | RDH16 | 8608 | 40437 | 0.5877 | 0.0000 | |
| GSE53624 | RDH16 | 8608 | 40437 | 0.5329 | 0.0000 | |
| GSE63941 | RDH16 | 8608 | 206753_at | 0.4151 | 0.1959 | |
| GSE77861 | RDH16 | 8608 | 206753_at | 0.1461 | 0.5320 | |
| GSE97050 | RDH16 | 8608 | A_23_P36484 | 0.2087 | 0.4008 | |
| SRP007169 | RDH16 | 8608 | RNAseq | -0.2705 | 0.6755 | |
| SRP064894 | RDH16 | 8608 | RNAseq | 1.3448 | 0.0000 | |
| SRP133303 | RDH16 | 8608 | RNAseq | 0.1526 | 0.1929 | |
| SRP159526 | RDH16 | 8608 | RNAseq | 0.5736 | 0.1153 | |
| SRP193095 | RDH16 | 8608 | RNAseq | 0.3173 | 0.0123 | |
| TCGA | RDH16 | 8608 | RNAseq | 1.4379 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by RDH16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RDH16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RDH16 | 8608 | 7 | 1 | 22 | |
| GSE20123 | RDH16 | 8608 | 7 | 0 | 23 | |
| GSE43470 | RDH16 | 8608 | 3 | 0 | 40 | |
| GSE46452 | RDH16 | 8608 | 8 | 1 | 50 | |
| GSE47630 | RDH16 | 8608 | 10 | 2 | 28 | |
| GSE54993 | RDH16 | 8608 | 0 | 5 | 65 | |
| GSE54994 | RDH16 | 8608 | 4 | 1 | 48 | |
| GSE60625 | RDH16 | 8608 | 0 | 0 | 11 | |
| GSE74703 | RDH16 | 8608 | 3 | 0 | 33 | |
| GSE74704 | RDH16 | 8608 | 4 | 0 | 16 | |
| TCGA | RDH16 | 8608 | 14 | 10 | 72 |
Total number of gains: 60; Total number of losses: 20; Total Number of normals: 408.
Somatic mutations of RDH16:
Generating mutation plots.
Highly correlated genes for RDH16:
Showing top 20/87 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RDH16 | QRFPR | 0.677622 | 3 | 0 | 3 |
| RDH16 | MAPK6 | 0.657021 | 4 | 0 | 4 |
| RDH16 | NOTCH3 | 0.618864 | 3 | 0 | 3 |
| RDH16 | WFDC5 | 0.617103 | 6 | 0 | 5 |
| RDH16 | NUAK1 | 0.601405 | 3 | 0 | 3 |
| RDH16 | S100A7A | 0.593556 | 4 | 0 | 3 |
| RDH16 | PIP4K2C | 0.592974 | 3 | 0 | 3 |
| RDH16 | GSS | 0.587475 | 5 | 0 | 4 |
| RDH16 | SH3BP1 | 0.587075 | 4 | 0 | 3 |
| RDH16 | HOXC13 | 0.58189 | 9 | 0 | 6 |
| RDH16 | NIPAL4 | 0.580465 | 4 | 0 | 4 |
| RDH16 | C16orf74 | 0.577894 | 5 | 0 | 3 |
| RDH16 | SPRR2G | 0.574847 | 5 | 0 | 4 |
| RDH16 | SLC36A1 | 0.570656 | 5 | 0 | 3 |
| RDH16 | KCNIP2-AS1 | 0.568669 | 3 | 0 | 3 |
| RDH16 | MAP6D1 | 0.563403 | 5 | 0 | 3 |
| RDH16 | PKMYT1 | 0.563295 | 5 | 0 | 3 |
| RDH16 | TUBAL3 | 0.562732 | 4 | 0 | 3 |
| RDH16 | CASP14 | 0.560168 | 4 | 0 | 3 |
| RDH16 | STRA6 | 0.560004 | 7 | 0 | 4 |
For details and further investigation, click here
