| Full name: CBFA2/RUNX1 partner transcriptional co-repressor 3 | Alias Symbol: MTGR2|ZMYND4|MTG16|RUNX1T3|ETO2 | ||
| Type: protein-coding gene | Cytoband: 16q24.3 | ||
| Entrez ID: 863 | HGNC ID: HGNC:1537 | Ensembl Gene: ENSG00000129993 | OMIM ID: 603870 |
| Drug and gene relationship at DGIdb | |||
Expression of CBFA2T3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CBFA2T3 | 863 | 208056_s_at | -0.0859 | 0.8724 | |
| GSE20347 | CBFA2T3 | 863 | 208056_s_at | 0.0078 | 0.9509 | |
| GSE23400 | CBFA2T3 | 863 | 208056_s_at | -0.1236 | 0.0003 | |
| GSE26886 | CBFA2T3 | 863 | 208056_s_at | -0.2296 | 0.4234 | |
| GSE29001 | CBFA2T3 | 863 | 208056_s_at | -0.0332 | 0.9213 | |
| GSE38129 | CBFA2T3 | 863 | 208056_s_at | -0.2962 | 0.0392 | |
| GSE45670 | CBFA2T3 | 863 | 208056_s_at | -0.2286 | 0.1500 | |
| GSE53622 | CBFA2T3 | 863 | 48753 | 0.0594 | 0.4367 | |
| GSE53624 | CBFA2T3 | 863 | 48753 | -0.0514 | 0.4496 | |
| GSE63941 | CBFA2T3 | 863 | 208056_s_at | 0.4945 | 0.3695 | |
| GSE77861 | CBFA2T3 | 863 | 208056_s_at | 0.0557 | 0.7728 | |
| GSE97050 | CBFA2T3 | 863 | A_23_P500741 | -0.0359 | 0.8674 | |
| SRP064894 | CBFA2T3 | 863 | RNAseq | -0.3202 | 0.3092 | |
| SRP133303 | CBFA2T3 | 863 | RNAseq | -0.5256 | 0.0012 | |
| SRP159526 | CBFA2T3 | 863 | RNAseq | -0.4180 | 0.1338 | |
| SRP193095 | CBFA2T3 | 863 | RNAseq | 0.4299 | 0.1593 | |
| SRP219564 | CBFA2T3 | 863 | RNAseq | 0.1366 | 0.8063 | |
| TCGA | CBFA2T3 | 863 | RNAseq | -0.3883 | 0.0424 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CBFA2T3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CBFA2T3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CBFA2T3 | 863 | 4 | 3 | 23 | |
| GSE20123 | CBFA2T3 | 863 | 4 | 3 | 23 | |
| GSE43470 | CBFA2T3 | 863 | 1 | 13 | 29 | |
| GSE46452 | CBFA2T3 | 863 | 38 | 1 | 20 | |
| GSE47630 | CBFA2T3 | 863 | 11 | 9 | 20 | |
| GSE54993 | CBFA2T3 | 863 | 3 | 4 | 63 | |
| GSE54994 | CBFA2T3 | 863 | 9 | 11 | 33 | |
| GSE60625 | CBFA2T3 | 863 | 4 | 0 | 7 | |
| GSE74703 | CBFA2T3 | 863 | 1 | 9 | 26 | |
| GSE74704 | CBFA2T3 | 863 | 3 | 2 | 15 | |
| TCGA | CBFA2T3 | 863 | 28 | 15 | 53 |
Total number of gains: 106; Total number of losses: 70; Total Number of normals: 312.
Somatic mutations of CBFA2T3:
Generating mutation plots.
Highly correlated genes for CBFA2T3:
Showing top 20/166 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CBFA2T3 | RCSD1 | 0.745064 | 3 | 0 | 3 |
| CBFA2T3 | RSPH9 | 0.67707 | 4 | 0 | 3 |
| CBFA2T3 | CARD11 | 0.670412 | 4 | 0 | 3 |
| CBFA2T3 | IGF2 | 0.664555 | 3 | 0 | 3 |
| CBFA2T3 | PRKCB | 0.64399 | 6 | 0 | 5 |
| CBFA2T3 | NFASC | 0.637915 | 3 | 0 | 3 |
| CBFA2T3 | LAMA4 | 0.637679 | 3 | 0 | 3 |
| CBFA2T3 | TNFRSF1B | 0.637677 | 7 | 0 | 6 |
| CBFA2T3 | S100B | 0.635674 | 3 | 0 | 3 |
| CBFA2T3 | TCF23 | 0.632645 | 3 | 0 | 3 |
| CBFA2T3 | OMP | 0.632139 | 3 | 0 | 3 |
| CBFA2T3 | ARHGDIB | 0.631802 | 5 | 0 | 5 |
| CBFA2T3 | CSH1 | 0.631367 | 4 | 0 | 4 |
| CBFA2T3 | MATN4 | 0.628792 | 3 | 0 | 3 |
| CBFA2T3 | KIRREL2 | 0.628671 | 3 | 0 | 3 |
| CBFA2T3 | CD74 | 0.620355 | 5 | 0 | 4 |
| CBFA2T3 | IL16 | 0.619713 | 6 | 0 | 5 |
| CBFA2T3 | APOL4 | 0.61888 | 3 | 0 | 3 |
| CBFA2T3 | VWA5B1 | 0.617453 | 4 | 0 | 3 |
| CBFA2T3 | UNC5A | 0.615413 | 4 | 0 | 4 |
For details and further investigation, click here
