| Full name: coiled-coil domain containing 43 | Alias Symbol: FLJ31795 | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 124808 | HGNC ID: HGNC:26472 | Ensembl Gene: ENSG00000180329 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC43:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC43 | 124808 | 225607_at | 0.2343 | 0.5690 | |
| GSE26886 | CCDC43 | 124808 | 225607_at | -0.4375 | 0.0190 | |
| GSE45670 | CCDC43 | 124808 | 225607_at | 0.2050 | 0.0660 | |
| GSE53622 | CCDC43 | 124808 | 83200 | 0.2415 | 0.0001 | |
| GSE53624 | CCDC43 | 124808 | 83200 | 0.2089 | 0.0163 | |
| GSE63941 | CCDC43 | 124808 | 225607_at | -0.6745 | 0.1145 | |
| GSE77861 | CCDC43 | 124808 | 225607_at | 0.3592 | 0.0617 | |
| GSE97050 | CCDC43 | 124808 | A_24_P39724 | 0.1419 | 0.5277 | |
| SRP007169 | CCDC43 | 124808 | RNAseq | 0.1661 | 0.6814 | |
| SRP008496 | CCDC43 | 124808 | RNAseq | 0.1386 | 0.5999 | |
| SRP064894 | CCDC43 | 124808 | RNAseq | 0.4350 | 0.0049 | |
| SRP133303 | CCDC43 | 124808 | RNAseq | 0.3269 | 0.0161 | |
| SRP159526 | CCDC43 | 124808 | RNAseq | 0.2417 | 0.0946 | |
| SRP193095 | CCDC43 | 124808 | RNAseq | -0.1114 | 0.2992 | |
| SRP219564 | CCDC43 | 124808 | RNAseq | 0.3453 | 0.3261 | |
| TCGA | CCDC43 | 124808 | RNAseq | 0.1433 | 0.0100 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCDC43 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC43:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC43 | 124808 | 6 | 2 | 22 | |
| GSE20123 | CCDC43 | 124808 | 6 | 2 | 22 | |
| GSE43470 | CCDC43 | 124808 | 1 | 2 | 40 | |
| GSE46452 | CCDC43 | 124808 | 32 | 0 | 27 | |
| GSE47630 | CCDC43 | 124808 | 9 | 0 | 31 | |
| GSE54993 | CCDC43 | 124808 | 3 | 4 | 63 | |
| GSE54994 | CCDC43 | 124808 | 8 | 5 | 40 | |
| GSE60625 | CCDC43 | 124808 | 4 | 0 | 7 | |
| GSE74703 | CCDC43 | 124808 | 1 | 1 | 34 | |
| GSE74704 | CCDC43 | 124808 | 4 | 1 | 15 | |
| TCGA | CCDC43 | 124808 | 27 | 6 | 63 |
Total number of gains: 101; Total number of losses: 23; Total Number of normals: 364.
Somatic mutations of CCDC43:
Generating mutation plots.
Highly correlated genes for CCDC43:
Showing top 20/46 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC43 | HIVEP2 | 0.71035 | 3 | 0 | 3 |
| CCDC43 | NPL | 0.667721 | 3 | 0 | 3 |
| CCDC43 | TCHH | 0.666302 | 3 | 0 | 3 |
| CCDC43 | PRMT5 | 0.644584 | 4 | 0 | 3 |
| CCDC43 | IRGQ | 0.644477 | 4 | 0 | 4 |
| CCDC43 | MICALL1 | 0.643248 | 3 | 0 | 3 |
| CCDC43 | PSMB5 | 0.641382 | 7 | 0 | 5 |
| CCDC43 | CDK17 | 0.6373 | 3 | 0 | 3 |
| CCDC43 | PAFAH1B2 | 0.635653 | 3 | 0 | 3 |
| CCDC43 | CSGALNACT2 | 0.620135 | 5 | 0 | 4 |
| CCDC43 | CUL4A | 0.613526 | 4 | 0 | 3 |
| CCDC43 | TAF1B | 0.613129 | 5 | 0 | 3 |
| CCDC43 | PDCL | 0.612188 | 4 | 0 | 3 |
| CCDC43 | SOX6 | 0.609914 | 3 | 0 | 3 |
| CCDC43 | TMEM101 | 0.605854 | 5 | 0 | 3 |
| CCDC43 | YIPF5 | 0.602046 | 4 | 0 | 4 |
| CCDC43 | CLTC | 0.599334 | 5 | 0 | 3 |
| CCDC43 | EIF1AD | 0.595445 | 5 | 0 | 4 |
| CCDC43 | ATG16L1 | 0.594133 | 5 | 0 | 3 |
| CCDC43 | PRPF39 | 0.593314 | 4 | 0 | 3 |
For details and further investigation, click here
