| Full name: platelet activating factor acetylhydrolase 1b catalytic subunit 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q23 | ||
| Entrez ID: 5049 | HGNC ID: HGNC:8575 | Ensembl Gene: ENSG00000168092 | OMIM ID: 602508 |
| Drug and gene relationship at DGIdb | |||
Expression of PAFAH1B2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAFAH1B2 | 5049 | 224777_s_at | 0.5177 | 0.0348 | |
| GSE20347 | PAFAH1B2 | 5049 | 210160_at | 0.0479 | 0.5079 | |
| GSE23400 | PAFAH1B2 | 5049 | 210160_at | 0.0963 | 0.0256 | |
| GSE26886 | PAFAH1B2 | 5049 | 224777_s_at | 0.4283 | 0.0246 | |
| GSE29001 | PAFAH1B2 | 5049 | 210160_at | -0.1336 | 0.5085 | |
| GSE38129 | PAFAH1B2 | 5049 | 210160_at | 0.0503 | 0.5599 | |
| GSE45670 | PAFAH1B2 | 5049 | 224777_s_at | 0.1950 | 0.1189 | |
| GSE53622 | PAFAH1B2 | 5049 | 28929 | 0.3571 | 0.0000 | |
| GSE53624 | PAFAH1B2 | 5049 | 117134 | 0.2921 | 0.0003 | |
| GSE63941 | PAFAH1B2 | 5049 | 224777_s_at | -1.1215 | 0.0073 | |
| GSE77861 | PAFAH1B2 | 5049 | 224777_s_at | 0.7433 | 0.0149 | |
| GSE97050 | PAFAH1B2 | 5049 | A_23_P255503 | 0.2372 | 0.3530 | |
| SRP007169 | PAFAH1B2 | 5049 | RNAseq | -0.4436 | 0.2492 | |
| SRP008496 | PAFAH1B2 | 5049 | RNAseq | 0.0227 | 0.9149 | |
| SRP064894 | PAFAH1B2 | 5049 | RNAseq | 0.2670 | 0.0527 | |
| SRP133303 | PAFAH1B2 | 5049 | RNAseq | 0.2819 | 0.0193 | |
| SRP159526 | PAFAH1B2 | 5049 | RNAseq | 0.0750 | 0.7955 | |
| SRP193095 | PAFAH1B2 | 5049 | RNAseq | -0.0714 | 0.5624 | |
| SRP219564 | PAFAH1B2 | 5049 | RNAseq | 0.1695 | 0.5383 | |
| TCGA | PAFAH1B2 | 5049 | RNAseq | 0.0395 | 0.4926 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PAFAH1B2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PAFAH1B2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAFAH1B2 | 5049 | 1 | 13 | 16 | |
| GSE20123 | PAFAH1B2 | 5049 | 1 | 13 | 16 | |
| GSE43470 | PAFAH1B2 | 5049 | 2 | 8 | 33 | |
| GSE46452 | PAFAH1B2 | 5049 | 3 | 26 | 30 | |
| GSE47630 | PAFAH1B2 | 5049 | 2 | 19 | 19 | |
| GSE54993 | PAFAH1B2 | 5049 | 10 | 0 | 60 | |
| GSE54994 | PAFAH1B2 | 5049 | 5 | 19 | 29 | |
| GSE60625 | PAFAH1B2 | 5049 | 0 | 3 | 8 | |
| GSE74703 | PAFAH1B2 | 5049 | 1 | 5 | 30 | |
| GSE74704 | PAFAH1B2 | 5049 | 0 | 9 | 11 | |
| TCGA | PAFAH1B2 | 5049 | 6 | 50 | 40 |
Total number of gains: 31; Total number of losses: 165; Total Number of normals: 292.
Somatic mutations of PAFAH1B2:
Generating mutation plots.
Highly correlated genes for PAFAH1B2:
Showing top 20/374 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAFAH1B2 | LACTB2 | 0.751728 | 3 | 0 | 3 |
| PAFAH1B2 | KMT2A | 0.715603 | 3 | 0 | 3 |
| PAFAH1B2 | FAM118B | 0.697374 | 4 | 0 | 4 |
| PAFAH1B2 | PNO1 | 0.692862 | 3 | 0 | 3 |
| PAFAH1B2 | SGTB | 0.692845 | 3 | 0 | 3 |
| PAFAH1B2 | LINC00621 | 0.675804 | 4 | 0 | 4 |
| PAFAH1B2 | ZFP1 | 0.665429 | 3 | 0 | 3 |
| PAFAH1B2 | YWHAG | 0.664774 | 3 | 0 | 3 |
| PAFAH1B2 | TTL | 0.658353 | 6 | 0 | 5 |
| PAFAH1B2 | ADPGK | 0.654071 | 6 | 0 | 4 |
| PAFAH1B2 | TNFAIP1 | 0.652907 | 4 | 0 | 3 |
| PAFAH1B2 | SPATA2 | 0.647775 | 3 | 0 | 3 |
| PAFAH1B2 | MSTO1 | 0.643378 | 3 | 0 | 3 |
| PAFAH1B2 | FAM217B | 0.642758 | 5 | 0 | 4 |
| PAFAH1B2 | DOCK7 | 0.639188 | 5 | 0 | 4 |
| PAFAH1B2 | TAS2R14 | 0.63602 | 3 | 0 | 3 |
| PAFAH1B2 | CCDC43 | 0.635653 | 3 | 0 | 3 |
| PAFAH1B2 | STPG1 | 0.635582 | 3 | 0 | 3 |
| PAFAH1B2 | DHX15 | 0.633889 | 3 | 0 | 3 |
| PAFAH1B2 | STIM2 | 0.633328 | 6 | 0 | 5 |
For details and further investigation, click here
