| Full name: TATA-box binding protein associated factor, RNA polymerase I subunit B | Alias Symbol: TAFI63|SL1|RAF1B|RAFI63 | ||
| Type: protein-coding gene | Cytoband: 2p25.1 | ||
| Entrez ID: 9014 | HGNC ID: HGNC:11533 | Ensembl Gene: ENSG00000115750 | OMIM ID: 604904 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TAF1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAF1B | 9014 | 216941_s_at | 0.3673 | 0.5786 | |
| GSE20347 | TAF1B | 9014 | 216941_s_at | 0.0015 | 0.9962 | |
| GSE23400 | TAF1B | 9014 | 216941_s_at | 0.1406 | 0.0020 | |
| GSE26886 | TAF1B | 9014 | 216941_s_at | -0.4756 | 0.1099 | |
| GSE29001 | TAF1B | 9014 | 216941_s_at | 0.1923 | 0.4420 | |
| GSE38129 | TAF1B | 9014 | 216941_s_at | 0.2228 | 0.1885 | |
| GSE45670 | TAF1B | 9014 | 216941_s_at | 0.1569 | 0.4130 | |
| GSE53622 | TAF1B | 9014 | 72658 | 0.2556 | 0.0013 | |
| GSE53624 | TAF1B | 9014 | 72658 | 0.1191 | 0.1122 | |
| GSE63941 | TAF1B | 9014 | 216941_s_at | -0.1673 | 0.7646 | |
| GSE77861 | TAF1B | 9014 | 216941_s_at | 0.1127 | 0.4594 | |
| GSE97050 | TAF1B | 9014 | A_33_P3392802 | 0.2235 | 0.3714 | |
| SRP007169 | TAF1B | 9014 | RNAseq | -0.3120 | 0.5276 | |
| SRP008496 | TAF1B | 9014 | RNAseq | -0.2993 | 0.2713 | |
| SRP064894 | TAF1B | 9014 | RNAseq | -0.2621 | 0.2536 | |
| SRP133303 | TAF1B | 9014 | RNAseq | 0.2213 | 0.2110 | |
| SRP159526 | TAF1B | 9014 | RNAseq | 0.2755 | 0.3150 | |
| SRP193095 | TAF1B | 9014 | RNAseq | -0.0043 | 0.9777 | |
| SRP219564 | TAF1B | 9014 | RNAseq | -0.4112 | 0.3587 | |
| TCGA | TAF1B | 9014 | RNAseq | 0.2564 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAF1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAF1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAF1B | 9014 | 11 | 2 | 17 | |
| GSE20123 | TAF1B | 9014 | 11 | 2 | 17 | |
| GSE43470 | TAF1B | 9014 | 3 | 1 | 39 | |
| GSE46452 | TAF1B | 9014 | 3 | 4 | 52 | |
| GSE47630 | TAF1B | 9014 | 7 | 0 | 33 | |
| GSE54993 | TAF1B | 9014 | 0 | 7 | 63 | |
| GSE54994 | TAF1B | 9014 | 11 | 0 | 42 | |
| GSE60625 | TAF1B | 9014 | 0 | 3 | 8 | |
| GSE74703 | TAF1B | 9014 | 2 | 0 | 34 | |
| GSE74704 | TAF1B | 9014 | 9 | 1 | 10 | |
| TCGA | TAF1B | 9014 | 34 | 5 | 57 |
Total number of gains: 91; Total number of losses: 25; Total Number of normals: 372.
Somatic mutations of TAF1B:
Generating mutation plots.
Highly correlated genes for TAF1B:
Showing top 20/22 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAF1B | LRR1 | 0.733371 | 3 | 0 | 3 |
| TAF1B | ZNF264 | 0.688719 | 3 | 0 | 3 |
| TAF1B | RIT1 | 0.680872 | 3 | 0 | 3 |
| TAF1B | CCDC43 | 0.613129 | 5 | 0 | 3 |
| TAF1B | TMEM87B | 0.605711 | 3 | 0 | 3 |
| TAF1B | FBXO22 | 0.604509 | 5 | 0 | 4 |
| TAF1B | CHAC2 | 0.585984 | 4 | 0 | 3 |
| TAF1B | RABGGTB | 0.556512 | 5 | 0 | 4 |
| TAF1B | SUV39H2 | 0.551796 | 7 | 0 | 3 |
| TAF1B | CBX3 | 0.541368 | 5 | 0 | 3 |
| TAF1B | HDAC4 | 0.537083 | 4 | 0 | 3 |
| TAF1B | TANK | 0.534484 | 6 | 0 | 3 |
| TAF1B | RAD54B | 0.53284 | 6 | 0 | 3 |
| TAF1B | ETAA1 | 0.529466 | 10 | 0 | 6 |
| TAF1B | PRMT3 | 0.529133 | 9 | 0 | 3 |
| TAF1B | AVL9 | 0.527717 | 4 | 0 | 3 |
| TAF1B | SLC5A6 | 0.524788 | 6 | 0 | 3 |
| TAF1B | POLE2 | 0.516191 | 8 | 0 | 4 |
| TAF1B | ACAT2 | 0.503717 | 7 | 0 | 3 |
| TAF1B | KIF4A | 0.501679 | 7 | 0 | 3 |
For details and further investigation, click here
