IRGQ

 

Full name: immunity related GTPase Q Alias Symbol: FKSG27
Type: protein-coding gene Cytoband: 19q13.31
Entrez ID: 126298 HGNC ID: HGNC:24868 Ensembl Gene: ENSG00000167378 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of IRGQ:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 IRGQ 126298 221877_at 0.1672 0.5436
GSE20347 IRGQ 126298 221877_at 0.0273 0.7928
GSE23400 IRGQ 126298 221877_at -0.2142 0.0000
GSE26886 IRGQ 126298 1555833_a_at -0.8421 0.0000
GSE29001 IRGQ 126298 221877_at 0.1202 0.7691
GSE38129 IRGQ 126298 221877_at 0.0023 0.9837
GSE45670 IRGQ 126298 1555833_a_at 0.2518 0.0149
GSE53622 IRGQ 126298 130408 0.0576 0.3852
GSE53624 IRGQ 126298 130408 0.0350 0.6871
GSE63941 IRGQ 126298 221877_at -1.2371 0.0016
GSE77861 IRGQ 126298 221877_at 0.0807 0.6099
GSE97050 IRGQ 126298 A_33_P3415913 -0.0051 0.9823
SRP007169 IRGQ 126298 RNAseq 0.1916 0.6121
SRP008496 IRGQ 126298 RNAseq 0.0316 0.8868
SRP064894 IRGQ 126298 RNAseq 0.2601 0.1321
SRP133303 IRGQ 126298 RNAseq 0.1537 0.2707
SRP159526 IRGQ 126298 RNAseq 0.4319 0.1634
SRP193095 IRGQ 126298 RNAseq 0.2000 0.0445
SRP219564 IRGQ 126298 RNAseq -0.2430 0.3646
TCGA IRGQ 126298 RNAseq -0.0936 0.1035

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by IRGQ expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of IRGQ:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 IRGQ 126298 6 5 19
GSE20123 IRGQ 126298 5 4 21
GSE43470 IRGQ 126298 4 11 28
GSE46452 IRGQ 126298 45 1 13
GSE47630 IRGQ 126298 8 6 26
GSE54993 IRGQ 126298 17 4 49
GSE54994 IRGQ 126298 6 12 35
GSE60625 IRGQ 126298 9 0 2
GSE74703 IRGQ 126298 4 7 25
GSE74704 IRGQ 126298 4 2 14
TCGA IRGQ 126298 14 16 66

Total number of gains: 122; Total number of losses: 68; Total Number of normals: 298.  

 

Somatic mutations of IRGQ:

 

Generating mutation plots.

 

Highly correlated genes for IRGQ:

 

Showing top 20/68 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
IRGQSUDS30.724827303
IRGQWDR600.716946303
IRGQGFRA40.713656303
IRGQZNF5690.701236303
IRGQOSBPL50.699425303
IRGQDCDC10.692186303
IRGQADAMTS170.686716303
IRGQING50.672174403
IRGQENPP70.666895404
IRGQSTRC0.662878303
IRGQFGF50.656654303
IRGQFANK10.652916303
IRGQZNF7630.646561404
IRGQUMODL10.645601403
IRGQCCDC430.644477404
IRGQIKBKB0.642693403
IRGQCOPS7B0.637954603
IRGQGPAM0.632398303
IRGQCD720.629575404
IRGQABCD30.627064403

For details and further investigation, click here