| Full name: myeloid cell nuclear differentiation antigen | Alias Symbol: PYHIN3 | ||
| Type: protein-coding gene | Cytoband: 1q23.1 | ||
| Entrez ID: 4332 | HGNC ID: HGNC:7183 | Ensembl Gene: ENSG00000163563 | OMIM ID: 159553 |
| Drug and gene relationship at DGIdb | |||
Expression of MNDA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MNDA | 4332 | 204959_at | 1.0261 | 0.3636 | |
| GSE20347 | MNDA | 4332 | 204959_at | 0.3676 | 0.0639 | |
| GSE23400 | MNDA | 4332 | 204959_at | 0.2668 | 0.0008 | |
| GSE26886 | MNDA | 4332 | 204959_at | -1.0852 | 0.0134 | |
| GSE29001 | MNDA | 4332 | 204959_at | 0.7961 | 0.0838 | |
| GSE38129 | MNDA | 4332 | 204959_at | 0.5822 | 0.0959 | |
| GSE45670 | MNDA | 4332 | 204959_at | 0.0428 | 0.9514 | |
| GSE53622 | MNDA | 4332 | 3926 | 0.2735 | 0.1085 | |
| GSE53624 | MNDA | 4332 | 3926 | 0.5193 | 0.0015 | |
| GSE63941 | MNDA | 4332 | 204959_at | 0.1529 | 0.2518 | |
| GSE77861 | MNDA | 4332 | 204959_at | 0.0202 | 0.9167 | |
| GSE97050 | MNDA | 4332 | A_23_P137935 | 0.0206 | 0.9599 | |
| SRP007169 | MNDA | 4332 | RNAseq | 1.6771 | 0.0978 | |
| SRP064894 | MNDA | 4332 | RNAseq | 0.6787 | 0.0475 | |
| SRP133303 | MNDA | 4332 | RNAseq | 0.9957 | 0.0022 | |
| SRP159526 | MNDA | 4332 | RNAseq | 0.9608 | 0.2893 | |
| SRP193095 | MNDA | 4332 | RNAseq | 1.5673 | 0.0000 | |
| SRP219564 | MNDA | 4332 | RNAseq | 1.2486 | 0.0501 | |
| TCGA | MNDA | 4332 | RNAseq | 0.7238 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by MNDA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MNDA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MNDA | 4332 | 8 | 0 | 22 | |
| GSE20123 | MNDA | 4332 | 8 | 0 | 22 | |
| GSE43470 | MNDA | 4332 | 7 | 2 | 34 | |
| GSE46452 | MNDA | 4332 | 2 | 1 | 56 | |
| GSE47630 | MNDA | 4332 | 14 | 0 | 26 | |
| GSE54993 | MNDA | 4332 | 0 | 5 | 65 | |
| GSE54994 | MNDA | 4332 | 16 | 0 | 37 | |
| GSE60625 | MNDA | 4332 | 0 | 0 | 11 | |
| GSE74703 | MNDA | 4332 | 7 | 2 | 27 | |
| GSE74704 | MNDA | 4332 | 3 | 0 | 17 | |
| TCGA | MNDA | 4332 | 41 | 3 | 52 |
Total number of gains: 106; Total number of losses: 13; Total Number of normals: 369.
Somatic mutations of MNDA:
Generating mutation plots.
Highly correlated genes for MNDA:
Showing top 20/475 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MNDA | C19orf38 | 0.797251 | 3 | 0 | 3 |
| MNDA | FCGR3A | 0.78396 | 3 | 0 | 3 |
| MNDA | SNX20 | 0.770853 | 6 | 0 | 6 |
| MNDA | CCL3 | 0.770077 | 3 | 0 | 3 |
| MNDA | NLE1 | 0.76185 | 3 | 0 | 3 |
| MNDA | C5AR1 | 0.753601 | 9 | 0 | 9 |
| MNDA | TYROBP | 0.74256 | 11 | 0 | 9 |
| MNDA | C3AR1 | 0.738247 | 11 | 0 | 11 |
| MNDA | CCRL2 | 0.729331 | 8 | 0 | 8 |
| MNDA | LCP2 | 0.722686 | 11 | 0 | 10 |
| MNDA | IGSF6 | 0.720521 | 10 | 0 | 10 |
| MNDA | CLEC12A | 0.71637 | 4 | 0 | 4 |
| MNDA | ST8SIA4 | 0.715917 | 7 | 0 | 7 |
| MNDA | CYBB | 0.715691 | 12 | 0 | 10 |
| MNDA | SUCNR1 | 0.712491 | 4 | 0 | 4 |
| MNDA | GPR65 | 0.71032 | 10 | 0 | 9 |
| MNDA | CD163 | 0.708858 | 11 | 0 | 10 |
| MNDA | CD86 | 0.708758 | 8 | 0 | 6 |
| MNDA | PLXNC1 | 0.707893 | 9 | 0 | 8 |
| MNDA | ARHGAP9 | 0.706814 | 6 | 0 | 6 |
For details and further investigation, click here
