CCR1

 

Full name: C-C motif chemokine receptor 1 Alias Symbol: CKR-1|MIP1aR|CD191
Type: protein-coding gene Cytoband: 3p21.31
Entrez ID: 1230 HGNC ID: HGNC:1602 Ensembl Gene: ENSG00000163823 OMIM ID: 601159
Drug and gene relationship at DGIdb

 

CCR1 involved pathways:

KEGG pathway Description View
hsa04062Chemokine signaling pathway

 

Expression of CCR1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CCR1 1230 205099_s_at 0.9345 0.3264
GSE20347 CCR1 1230 205099_s_at 0.8792 0.0004
GSE23400 CCR1 1230 205098_at 0.1578 0.0105
GSE26886 CCR1 1230 205098_at -0.2110 0.6023
GSE29001 CCR1 1230 205098_at 1.0375 0.0098
GSE38129 CCR1 1230 205099_s_at 0.7098 0.0004
GSE45670 CCR1 1230 205098_at 0.1426 0.7446
GSE53622 CCR1 1230 114212 0.7181 0.0002
GSE53624 CCR1 1230 114212 1.0487 0.0000
GSE63941 CCR1 1230 205099_s_at 0.0937 0.5939
GSE77861 CCR1 1230 205099_s_at 0.2065 0.0573
GSE97050 CCR1 1230 A_24_P148717 1.0166 0.1386
SRP007169 CCR1 1230 RNAseq 3.6021 0.0000
SRP008496 CCR1 1230 RNAseq 2.4899 0.0000
SRP064894 CCR1 1230 RNAseq 0.9266 0.0226
SRP133303 CCR1 1230 RNAseq 0.9954 0.0010
SRP159526 CCR1 1230 RNAseq 0.8550 0.2771
SRP193095 CCR1 1230 RNAseq 1.6334 0.0000
SRP219564 CCR1 1230 RNAseq 0.8015 0.2950
TCGA CCR1 1230 RNAseq 0.0482 0.7746

Upregulated datasets: 5; Downregulated datasets: 0.  

 

Survival by CCR1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CCR1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CCR1 1230 0 17 13
GSE20123 CCR1 1230 0 18 12
GSE43470 CCR1 1230 0 20 23
GSE46452 CCR1 1230 2 17 40
GSE47630 CCR1 1230 2 23 15
GSE54993 CCR1 1230 7 2 61
GSE54994 CCR1 1230 0 36 17
GSE60625 CCR1 1230 5 0 6
GSE74703 CCR1 1230 0 15 21
GSE74704 CCR1 1230 0 12 8
TCGA CCR1 1230 1 75 20

Total number of gains: 17; Total number of losses: 235; Total Number of normals: 236.  

 

Somatic mutations of CCR1:

 

Generating mutation plots.

 

Highly correlated genes for CCR1:

 

Showing top 20/685 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CCR1FCGR3A0.809154303
CCR1TFEC0.7798381009
CCR1TYROBP0.75846311011
CCR1PIK3R50.745054505
CCR1CD1630.74464510010
CCR1FCER1G0.73921911010
CCR1CYBB0.73420211010
CCR1C1QB0.73097611011
CCR1HAVCR20.730155505
CCR1SLC7A70.72499212010
CCR1LILRB20.72253111010
CCR1MS4A70.718696404
CCR1C19orf380.717905303
CCR1PLA2G70.71714912011
CCR1GJD30.714143404
CCR1CCR50.711016909
CCR1IGSF60.7094331109
CCR1CD530.702711909
CCR1MPEG10.702446606
CCR1ITGB20.7015511010

For details and further investigation, click here