| Full name: copine 1 | Alias Symbol: CPN1 | ||
| Type: protein-coding gene | Cytoband: 20q11.22 | ||
| Entrez ID: 8904 | HGNC ID: HGNC:2314 | Ensembl Gene: ENSG00000214078 | OMIM ID: 604205 |
| Drug and gene relationship at DGIdb | |||
Expression of CPNE1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPNE1 | 8904 | 206918_s_at | 1.0711 | 0.0505 | |
| GSE20347 | CPNE1 | 8904 | 206918_s_at | 0.2418 | 0.3863 | |
| GSE23400 | CPNE1 | 8904 | 206918_s_at | 0.3937 | 0.0001 | |
| GSE26886 | CPNE1 | 8904 | 206918_s_at | 0.3962 | 0.2519 | |
| GSE29001 | CPNE1 | 8904 | 206918_s_at | 0.6588 | 0.0390 | |
| GSE38129 | CPNE1 | 8904 | 206918_s_at | 0.3463 | 0.0749 | |
| GSE45670 | CPNE1 | 8904 | 206918_s_at | 0.4450 | 0.0174 | |
| GSE53622 | CPNE1 | 8904 | 20174 | 0.0358 | 0.5078 | |
| GSE53624 | CPNE1 | 8904 | 4552 | -0.1427 | 0.0650 | |
| GSE63941 | CPNE1 | 8904 | 206918_s_at | 1.4696 | 0.0374 | |
| GSE77861 | CPNE1 | 8904 | 206918_s_at | 0.1265 | 0.6181 | |
| GSE97050 | CPNE1 | 8904 | A_33_P3290888 | -0.0003 | 0.9988 | |
| SRP007169 | CPNE1 | 8904 | RNAseq | -0.3480 | 0.2850 | |
| SRP008496 | CPNE1 | 8904 | RNAseq | -0.6947 | 0.0005 | |
| SRP064894 | CPNE1 | 8904 | RNAseq | 0.6763 | 0.0000 | |
| SRP133303 | CPNE1 | 8904 | RNAseq | 0.4894 | 0.0099 | |
| SRP159526 | CPNE1 | 8904 | RNAseq | 0.3480 | 0.2148 | |
| SRP193095 | CPNE1 | 8904 | RNAseq | 0.5496 | 0.0000 | |
| SRP219564 | CPNE1 | 8904 | RNAseq | 0.9932 | 0.0009 | |
| TCGA | CPNE1 | 8904 | RNAseq | 0.2694 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CPNE1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CPNE1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPNE1 | 8904 | 15 | 1 | 14 | |
| GSE20123 | CPNE1 | 8904 | 15 | 1 | 14 | |
| GSE43470 | CPNE1 | 8904 | 12 | 0 | 31 | |
| GSE46452 | CPNE1 | 8904 | 29 | 0 | 30 | |
| GSE47630 | CPNE1 | 8904 | 25 | 0 | 15 | |
| GSE54993 | CPNE1 | 8904 | 0 | 17 | 53 | |
| GSE54994 | CPNE1 | 8904 | 24 | 0 | 29 | |
| GSE60625 | CPNE1 | 8904 | 0 | 0 | 11 | |
| GSE74703 | CPNE1 | 8904 | 11 | 0 | 25 | |
| GSE74704 | CPNE1 | 8904 | 11 | 0 | 9 | |
| TCGA | CPNE1 | 8904 | 49 | 3 | 44 |
Total number of gains: 191; Total number of losses: 22; Total Number of normals: 275.
Somatic mutations of CPNE1:
Generating mutation plots.
Highly correlated genes for CPNE1:
Showing top 20/499 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPNE1 | STARD7 | 0.796728 | 3 | 0 | 3 |
| CPNE1 | HIGD2A | 0.769665 | 3 | 0 | 3 |
| CPNE1 | MBD4 | 0.76157 | 3 | 0 | 3 |
| CPNE1 | ABCD4 | 0.760625 | 3 | 0 | 3 |
| CPNE1 | NUDCD1 | 0.759834 | 3 | 0 | 3 |
| CPNE1 | AP1AR | 0.756292 | 3 | 0 | 3 |
| CPNE1 | NAA25 | 0.754502 | 3 | 0 | 3 |
| CPNE1 | ZNF8 | 0.75381 | 3 | 0 | 3 |
| CPNE1 | SRPK2 | 0.751941 | 3 | 0 | 3 |
| CPNE1 | DTX4 | 0.745153 | 3 | 0 | 3 |
| CPNE1 | NEK11 | 0.731224 | 3 | 0 | 3 |
| CPNE1 | GPR158 | 0.721009 | 5 | 0 | 4 |
| CPNE1 | COMMD2 | 0.716403 | 3 | 0 | 3 |
| CPNE1 | CCT8 | 0.715018 | 3 | 0 | 3 |
| CPNE1 | MIS18A | 0.71483 | 4 | 0 | 4 |
| CPNE1 | PDRG1 | 0.709099 | 4 | 0 | 4 |
| CPNE1 | NAPEPLD | 0.70856 | 3 | 0 | 3 |
| CPNE1 | MED26 | 0.705851 | 3 | 0 | 3 |
| CPNE1 | KHDRBS1 | 0.705292 | 3 | 0 | 3 |
| CPNE1 | ARAP1 | 0.703267 | 3 | 0 | 3 |
For details and further investigation, click here
