| Full name: CD248 molecule | Alias Symbol: TEM1 | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 57124 | HGNC ID: HGNC:18219 | Ensembl Gene: ENSG00000174807 | OMIM ID: 606064 |
| Drug and gene relationship at DGIdb | |||
Expression of CD248:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD248 | 57124 | 219025_at | 0.7376 | 0.4015 | |
| GSE20347 | CD248 | 57124 | 219025_at | 0.3200 | 0.0072 | |
| GSE23400 | CD248 | 57124 | 219025_at | 0.0050 | 0.9604 | |
| GSE26886 | CD248 | 57124 | 219025_at | 0.8137 | 0.0000 | |
| GSE29001 | CD248 | 57124 | 219025_at | 0.2896 | 0.3366 | |
| GSE38129 | CD248 | 57124 | 219025_at | 0.0463 | 0.8161 | |
| GSE45670 | CD248 | 57124 | 219025_at | -0.3289 | 0.1382 | |
| GSE53622 | CD248 | 57124 | 61229 | 0.2395 | 0.0950 | |
| GSE53624 | CD248 | 57124 | 61229 | 0.6824 | 0.0000 | |
| GSE63941 | CD248 | 57124 | 219025_at | -2.4727 | 0.0000 | |
| GSE77861 | CD248 | 57124 | 219025_at | 0.1378 | 0.3921 | |
| GSE97050 | CD248 | 57124 | A_33_P3337485 | 0.1885 | 0.6196 | |
| SRP007169 | CD248 | 57124 | RNAseq | 2.2126 | 0.0006 | |
| SRP008496 | CD248 | 57124 | RNAseq | 2.8880 | 0.0000 | |
| SRP064894 | CD248 | 57124 | RNAseq | 1.2526 | 0.0036 | |
| SRP133303 | CD248 | 57124 | RNAseq | 0.3788 | 0.1920 | |
| SRP159526 | CD248 | 57124 | RNAseq | -0.0268 | 0.9620 | |
| SRP219564 | CD248 | 57124 | RNAseq | 1.6175 | 0.0818 | |
| TCGA | CD248 | 57124 | RNAseq | -0.0926 | 0.4269 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by CD248 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD248:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD248 | 57124 | 9 | 4 | 17 | |
| GSE20123 | CD248 | 57124 | 9 | 4 | 17 | |
| GSE43470 | CD248 | 57124 | 6 | 1 | 36 | |
| GSE46452 | CD248 | 57124 | 11 | 3 | 45 | |
| GSE47630 | CD248 | 57124 | 8 | 5 | 27 | |
| GSE54993 | CD248 | 57124 | 3 | 0 | 67 | |
| GSE54994 | CD248 | 57124 | 8 | 5 | 40 | |
| GSE60625 | CD248 | 57124 | 0 | 3 | 8 | |
| GSE74703 | CD248 | 57124 | 4 | 0 | 32 | |
| GSE74704 | CD248 | 57124 | 7 | 2 | 11 | |
| TCGA | CD248 | 57124 | 25 | 6 | 65 |
Total number of gains: 90; Total number of losses: 33; Total Number of normals: 365.
Somatic mutations of CD248:
Generating mutation plots.
Highly correlated genes for CD248:
Showing top 20/788 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD248 | C11orf96 | 0.732674 | 4 | 0 | 3 |
| CD248 | ANKS3 | 0.726137 | 3 | 0 | 3 |
| CD248 | A1BG | 0.722232 | 5 | 0 | 4 |
| CD248 | KCNQ1OT1 | 0.721493 | 3 | 0 | 3 |
| CD248 | KISS1R | 0.715896 | 3 | 0 | 3 |
| CD248 | MS4A14 | 0.71583 | 3 | 0 | 3 |
| CD248 | BICC1 | 0.707128 | 9 | 0 | 8 |
| CD248 | ACE | 0.705732 | 4 | 0 | 4 |
| CD248 | STS | 0.704946 | 3 | 0 | 3 |
| CD248 | FAT4 | 0.701569 | 4 | 0 | 4 |
| CD248 | ISLR | 0.697266 | 13 | 0 | 12 |
| CD248 | MXRA8 | 0.693785 | 13 | 0 | 11 |
| CD248 | PCOLCE | 0.693313 | 13 | 0 | 12 |
| CD248 | NKG7 | 0.688887 | 3 | 0 | 3 |
| CD248 | COL6A1 | 0.680812 | 13 | 0 | 12 |
| CD248 | HIC1 | 0.679859 | 7 | 0 | 7 |
| CD248 | LRRC17 | 0.676659 | 11 | 0 | 10 |
| CD248 | TFEB | 0.676472 | 4 | 0 | 3 |
| CD248 | ZNF804A | 0.675596 | 3 | 0 | 3 |
| CD248 | PDGFRB | 0.674726 | 13 | 0 | 12 |
For details and further investigation, click here
