MXRA8

 

Full name: matrix remodeling associated 8 Alias Symbol: DKFZp586E2023
Type: protein-coding gene Cytoband: 1p36.33
Entrez ID: 54587 HGNC ID: HGNC:7542 Ensembl Gene: ENSG00000162576 OMIM ID: 617293
Drug and gene relationship at DGIdb

 

Expression of MXRA8:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MXRA8 54587 213422_s_at 0.3708 0.5878
GSE20347 MXRA8 54587 213422_s_at 0.5872 0.0002
GSE23400 MXRA8 54587 213422_s_at 0.3398 0.0003
GSE26886 MXRA8 54587 213422_s_at 1.1011 0.0014
GSE29001 MXRA8 54587 213422_s_at 0.1764 0.5312
GSE38129 MXRA8 54587 213422_s_at 0.2063 0.3188
GSE45670 MXRA8 54587 213422_s_at -0.3617 0.0317
GSE53622 MXRA8 54587 136073 1.2918 0.0000
GSE53624 MXRA8 54587 136073 1.3360 0.0000
GSE63941 MXRA8 54587 213422_s_at -3.5927 0.0000
GSE77861 MXRA8 54587 213422_s_at 0.3055 0.1037
GSE97050 MXRA8 54587 A_24_P353905 0.5074 0.1707
SRP007169 MXRA8 54587 RNAseq 0.8116 0.1729
SRP008496 MXRA8 54587 RNAseq 1.6086 0.0004
SRP064894 MXRA8 54587 RNAseq 0.7999 0.0171
SRP133303 MXRA8 54587 RNAseq 0.4393 0.2089
SRP159526 MXRA8 54587 RNAseq 0.5072 0.2018
SRP193095 MXRA8 54587 RNAseq 0.6166 0.0239
SRP219564 MXRA8 54587 RNAseq -0.1552 0.6261
TCGA MXRA8 54587 RNAseq 0.0292 0.7954

Upregulated datasets: 4; Downregulated datasets: 1.  

 

Survival by MXRA8 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MXRA8:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MXRA8 54587 3 7 20
GSE20123 MXRA8 54587 3 6 21
GSE43470 MXRA8 54587 3 5 35
GSE46452 MXRA8 54587 7 1 51
GSE47630 MXRA8 54587 8 4 28
GSE54993 MXRA8 54587 2 2 66
GSE54994 MXRA8 54587 15 2 36
GSE60625 MXRA8 54587 0 0 11
GSE74703 MXRA8 54587 3 3 30
GSE74704 MXRA8 54587 3 0 17
TCGA MXRA8 54587 14 20 62

Total number of gains: 61; Total number of losses: 50; Total Number of normals: 377.  

 

Somatic mutations of MXRA8:

 

Generating mutation plots.

 

Highly correlated genes for MXRA8:

 

Showing top 20/964 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MXRA8ISLR0.80760213013
MXRA8CTSK0.76836412012
MXRA8COL6A20.76207713013
MXRA8COL6A10.7558813013
MXRA8NID20.754327909
MXRA8ANGPTL20.75069313012
MXRA8PCOLCE0.74841613013
MXRA8FNDC10.744116908
MXRA8AEBP10.74373513012
MXRA8MMP20.73999812011
MXRA8VCAN0.73870613012
MXRA8HTRA10.73500312012
MXRA8COL6A30.73364713012
MXRA8RARRES20.72922113011
MXRA8SULF10.72890212011
MXRA8EFEMP20.72748513012
MXRA8ADAMTS120.726679706
MXRA8COL8A10.72612611010
MXRA8PDGFRB0.72569413011
MXRA8ASPN0.72321711011

For details and further investigation, click here