| Full name: molybdenum cofactor sulfurase | Alias Symbol: HMCS|FLJ20733|MOS | ||
| Type: protein-coding gene | Cytoband: 18q12.2 | ||
| Entrez ID: 55034 | HGNC ID: HGNC:18234 | Ensembl Gene: ENSG00000075643 | OMIM ID: 613274 |
| Drug and gene relationship at DGIdb | |||
Expression of MOCOS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MOCOS | 55034 | 219959_at | 0.0846 | 0.9420 | |
| GSE20347 | MOCOS | 55034 | 219959_at | -0.0909 | 0.8113 | |
| GSE23400 | MOCOS | 55034 | 219959_at | 0.2733 | 0.0205 | |
| GSE26886 | MOCOS | 55034 | 219959_at | 0.2947 | 0.4848 | |
| GSE29001 | MOCOS | 55034 | 219959_at | 0.3541 | 0.5269 | |
| GSE38129 | MOCOS | 55034 | 219959_at | 0.2129 | 0.5079 | |
| GSE45670 | MOCOS | 55034 | 219959_at | 0.4000 | 0.4320 | |
| GSE53622 | MOCOS | 55034 | 13982 | -0.0092 | 0.9629 | |
| GSE53624 | MOCOS | 55034 | 13982 | -0.1146 | 0.3921 | |
| GSE63941 | MOCOS | 55034 | 219959_at | -0.3053 | 0.8320 | |
| GSE77861 | MOCOS | 55034 | 219959_at | -0.2186 | 0.7032 | |
| GSE97050 | MOCOS | 55034 | A_23_P67042 | 0.6488 | 0.1934 | |
| SRP007169 | MOCOS | 55034 | RNAseq | -1.2929 | 0.0329 | |
| SRP008496 | MOCOS | 55034 | RNAseq | -0.8164 | 0.0584 | |
| SRP064894 | MOCOS | 55034 | RNAseq | 0.3246 | 0.1163 | |
| SRP133303 | MOCOS | 55034 | RNAseq | 0.5726 | 0.0198 | |
| SRP159526 | MOCOS | 55034 | RNAseq | -0.4669 | 0.4542 | |
| SRP193095 | MOCOS | 55034 | RNAseq | 0.0935 | 0.5852 | |
| SRP219564 | MOCOS | 55034 | RNAseq | 0.7494 | 0.2441 | |
| TCGA | MOCOS | 55034 | RNAseq | 0.3974 | 0.0186 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MOCOS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MOCOS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MOCOS | 55034 | 2 | 5 | 23 | |
| GSE20123 | MOCOS | 55034 | 2 | 5 | 23 | |
| GSE43470 | MOCOS | 55034 | 0 | 3 | 40 | |
| GSE46452 | MOCOS | 55034 | 1 | 25 | 33 | |
| GSE47630 | MOCOS | 55034 | 5 | 20 | 15 | |
| GSE54993 | MOCOS | 55034 | 8 | 1 | 61 | |
| GSE54994 | MOCOS | 55034 | 1 | 16 | 36 | |
| GSE60625 | MOCOS | 55034 | 0 | 4 | 7 | |
| GSE74703 | MOCOS | 55034 | 0 | 3 | 33 | |
| GSE74704 | MOCOS | 55034 | 1 | 4 | 15 | |
| TCGA | MOCOS | 55034 | 15 | 40 | 41 |
Total number of gains: 35; Total number of losses: 126; Total Number of normals: 327.
Somatic mutations of MOCOS:
Generating mutation plots.
Highly correlated genes for MOCOS:
Showing top 20/43 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MOCOS | CD52 | 0.741302 | 3 | 0 | 3 |
| MOCOS | NCF4 | 0.67209 | 3 | 0 | 3 |
| MOCOS | SPAG4 | 0.660819 | 5 | 0 | 4 |
| MOCOS | DOCK2 | 0.640375 | 4 | 0 | 3 |
| MOCOS | KCTD5 | 0.616478 | 4 | 0 | 3 |
| MOCOS | IL15RA | 0.612652 | 5 | 0 | 3 |
| MOCOS | MFSD1 | 0.606371 | 5 | 0 | 4 |
| MOCOS | SDC1 | 0.600056 | 4 | 0 | 4 |
| MOCOS | CARD6 | 0.589382 | 5 | 0 | 3 |
| MOCOS | GJB5 | 0.588024 | 3 | 0 | 3 |
| MOCOS | DSP | 0.586605 | 6 | 0 | 5 |
| MOCOS | ERMP1 | 0.583351 | 4 | 0 | 3 |
| MOCOS | TRIM29 | 0.582686 | 3 | 0 | 3 |
| MOCOS | ULBP2 | 0.581495 | 4 | 0 | 3 |
| MOCOS | MAP7 | 0.572476 | 3 | 0 | 3 |
| MOCOS | SRD5A1 | 0.569883 | 4 | 0 | 3 |
| MOCOS | EVI2A | 0.569255 | 5 | 0 | 3 |
| MOCOS | PKP1 | 0.56782 | 4 | 0 | 3 |
| MOCOS | AP2S1 | 0.566998 | 5 | 0 | 3 |
| MOCOS | GCH1 | 0.565632 | 4 | 0 | 3 |
For details and further investigation, click here
