| Full name: CD82 molecule | Alias Symbol: R2|IA4|TSPAN27 | ||
| Type: protein-coding gene | Cytoband: 11p11.2 | ||
| Entrez ID: 3732 | HGNC ID: HGNC:6210 | Ensembl Gene: ENSG00000085117 | OMIM ID: 600623 |
| Drug and gene relationship at DGIdb | |||
CD82 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04115 | p53 signaling pathway |
Expression of CD82:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD82 | 3732 | 203904_x_at | -0.5150 | 0.3817 | |
| GSE20347 | CD82 | 3732 | 203904_x_at | -0.6696 | 0.0000 | |
| GSE23400 | CD82 | 3732 | 203904_x_at | -0.2693 | 0.0003 | |
| GSE26886 | CD82 | 3732 | 203904_x_at | -1.0516 | 0.0009 | |
| GSE29001 | CD82 | 3732 | 203904_x_at | -0.4450 | 0.0225 | |
| GSE38129 | CD82 | 3732 | 203904_x_at | -0.3931 | 0.0079 | |
| GSE45670 | CD82 | 3732 | 203904_x_at | 0.0630 | 0.7706 | |
| GSE53622 | CD82 | 3732 | 118856 | -0.4504 | 0.0008 | |
| GSE53624 | CD82 | 3732 | 118856 | -0.5556 | 0.0000 | |
| GSE63941 | CD82 | 3732 | 203904_x_at | -0.8355 | 0.0373 | |
| GSE77861 | CD82 | 3732 | 203904_x_at | -0.4573 | 0.0076 | |
| GSE97050 | CD82 | 3732 | A_23_P1782 | 0.4911 | 0.4166 | |
| SRP007169 | CD82 | 3732 | RNAseq | -1.8236 | 0.0000 | |
| SRP008496 | CD82 | 3732 | RNAseq | -1.4386 | 0.0000 | |
| SRP064894 | CD82 | 3732 | RNAseq | -0.1590 | 0.4062 | |
| SRP133303 | CD82 | 3732 | RNAseq | 0.0382 | 0.8903 | |
| SRP159526 | CD82 | 3732 | RNAseq | -1.2335 | 0.0005 | |
| SRP193095 | CD82 | 3732 | RNAseq | -0.5456 | 0.0018 | |
| SRP219564 | CD82 | 3732 | RNAseq | 0.0050 | 0.9929 | |
| TCGA | CD82 | 3732 | RNAseq | 0.1618 | 0.0362 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by CD82 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD82:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD82 | 3732 | 1 | 8 | 21 | |
| GSE20123 | CD82 | 3732 | 1 | 7 | 22 | |
| GSE43470 | CD82 | 3732 | 2 | 5 | 36 | |
| GSE46452 | CD82 | 3732 | 8 | 5 | 46 | |
| GSE47630 | CD82 | 3732 | 3 | 9 | 28 | |
| GSE54993 | CD82 | 3732 | 3 | 0 | 67 | |
| GSE54994 | CD82 | 3732 | 3 | 9 | 41 | |
| GSE60625 | CD82 | 3732 | 0 | 0 | 11 | |
| GSE74703 | CD82 | 3732 | 2 | 2 | 32 | |
| GSE74704 | CD82 | 3732 | 1 | 6 | 13 | |
| TCGA | CD82 | 3732 | 15 | 20 | 61 |
Total number of gains: 39; Total number of losses: 71; Total Number of normals: 378.
Somatic mutations of CD82:
Generating mutation plots.
Highly correlated genes for CD82:
Showing top 20/1004 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD82 | DAD1 | 0.795736 | 3 | 0 | 3 |
| CD82 | ELOVL1 | 0.750614 | 3 | 0 | 3 |
| CD82 | VPS25 | 0.729552 | 5 | 0 | 5 |
| CD82 | PGM2 | 0.718346 | 6 | 0 | 6 |
| CD82 | VSIG10L | 0.703679 | 4 | 0 | 4 |
| CD82 | PI4K2B | 0.69995 | 3 | 0 | 3 |
| CD82 | RABGGTA | 0.695614 | 10 | 0 | 9 |
| CD82 | SCARF1 | 0.695338 | 3 | 0 | 3 |
| CD82 | RAB42 | 0.693832 | 3 | 0 | 3 |
| CD82 | SFTA2 | 0.684047 | 3 | 0 | 3 |
| CD82 | NDOR1 | 0.680336 | 4 | 0 | 4 |
| CD82 | PEX11B | 0.680002 | 6 | 0 | 6 |
| CD82 | SMPD2 | 0.679861 | 10 | 0 | 10 |
| CD82 | NAGK | 0.679297 | 11 | 0 | 11 |
| CD82 | LDLRAD3 | 0.677998 | 4 | 0 | 4 |
| CD82 | SYTL4 | 0.677768 | 3 | 0 | 3 |
| CD82 | AMER2 | 0.673004 | 3 | 0 | 3 |
| CD82 | OCIAD1 | 0.671704 | 3 | 0 | 3 |
| CD82 | NLRP1 | 0.670405 | 4 | 0 | 3 |
| CD82 | TAX1BP3 | 0.667056 | 3 | 0 | 3 |
For details and further investigation, click here
