| Full name: phosphatidylinositol 4-kinase type 2 beta | Alias Symbol: PI4KIIB|FLJ11105|PIK42B | ||
| Type: protein-coding gene | Cytoband: 4p15.2 | ||
| Entrez ID: 55300 | HGNC ID: HGNC:18215 | Ensembl Gene: ENSG00000038210 | OMIM ID: 612101 |
| Drug and gene relationship at DGIdb | |||
Expression of PI4K2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | PI4K2B | 55300 | 87942 | -0.0367 | 0.7379 | |
| GSE53624 | PI4K2B | 55300 | 87942 | -0.1790 | 0.1428 | |
| GSE97050 | PI4K2B | 55300 | A_23_P18598 | 0.3898 | 0.2641 | |
| SRP007169 | PI4K2B | 55300 | RNAseq | 0.0108 | 0.9831 | |
| SRP008496 | PI4K2B | 55300 | RNAseq | 0.0256 | 0.9239 | |
| SRP064894 | PI4K2B | 55300 | RNAseq | 0.0818 | 0.7392 | |
| SRP133303 | PI4K2B | 55300 | RNAseq | -0.0656 | 0.6439 | |
| SRP159526 | PI4K2B | 55300 | RNAseq | -0.5617 | 0.0161 | |
| SRP193095 | PI4K2B | 55300 | RNAseq | -0.7634 | 0.0000 | |
| SRP219564 | PI4K2B | 55300 | RNAseq | -0.1552 | 0.7819 | |
| TCGA | PI4K2B | 55300 | RNAseq | -0.0542 | 0.2970 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PI4K2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PI4K2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PI4K2B | 55300 | 0 | 18 | 12 | |
| GSE20123 | PI4K2B | 55300 | 0 | 17 | 13 | |
| GSE43470 | PI4K2B | 55300 | 0 | 15 | 28 | |
| GSE46452 | PI4K2B | 55300 | 1 | 36 | 22 | |
| GSE47630 | PI4K2B | 55300 | 1 | 19 | 20 | |
| GSE54993 | PI4K2B | 55300 | 10 | 0 | 60 | |
| GSE54994 | PI4K2B | 55300 | 4 | 11 | 38 | |
| GSE60625 | PI4K2B | 55300 | 0 | 0 | 11 | |
| GSE74703 | PI4K2B | 55300 | 0 | 13 | 23 | |
| GSE74704 | PI4K2B | 55300 | 0 | 11 | 9 | |
| TCGA | PI4K2B | 55300 | 11 | 47 | 38 |
Total number of gains: 27; Total number of losses: 187; Total Number of normals: 274.
Somatic mutations of PI4K2B:
Generating mutation plots.
Highly correlated genes for PI4K2B:
Showing top 20/67 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PI4K2B | DHX15 | 0.743288 | 3 | 0 | 3 |
| PI4K2B | RBM7 | 0.727967 | 3 | 0 | 3 |
| PI4K2B | SCO1 | 0.715087 | 3 | 0 | 3 |
| PI4K2B | MRFAP1 | 0.71078 | 3 | 0 | 3 |
| PI4K2B | PRDX3 | 0.704401 | 3 | 0 | 3 |
| PI4K2B | SEC23IP | 0.701436 | 3 | 0 | 3 |
| PI4K2B | CD82 | 0.69995 | 3 | 0 | 3 |
| PI4K2B | CDC123 | 0.698185 | 3 | 0 | 3 |
| PI4K2B | ATG3 | 0.696791 | 3 | 0 | 3 |
| PI4K2B | SPCS1 | 0.695596 | 3 | 0 | 3 |
| PI4K2B | RPAP3 | 0.690184 | 3 | 0 | 3 |
| PI4K2B | IMP3 | 0.686611 | 3 | 0 | 3 |
| PI4K2B | SMC3 | 0.684202 | 3 | 0 | 3 |
| PI4K2B | COMMD8 | 0.684154 | 4 | 0 | 4 |
| PI4K2B | MTO1 | 0.683849 | 3 | 0 | 3 |
| PI4K2B | EPB41L5 | 0.681082 | 3 | 0 | 3 |
| PI4K2B | POLR2B | 0.679723 | 3 | 0 | 3 |
| PI4K2B | LAP3 | 0.675988 | 3 | 0 | 3 |
| PI4K2B | MFAP1 | 0.669577 | 3 | 0 | 3 |
| PI4K2B | AP1S3 | 0.668957 | 3 | 0 | 3 |
For details and further investigation, click here
