| Full name: cadherin 16 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 1014 | HGNC ID: HGNC:1755 | Ensembl Gene: ENSG00000166589 | OMIM ID: 603118 |
| Drug and gene relationship at DGIdb | |||
Expression of CDH16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDH16 | 1014 | 206517_at | -0.9749 | 0.2988 | |
| GSE20347 | CDH16 | 1014 | 206517_at | -0.2160 | 0.4835 | |
| GSE23400 | CDH16 | 1014 | 206517_at | -0.1901 | 0.0008 | |
| GSE26886 | CDH16 | 1014 | 206517_at | -0.8340 | 0.0006 | |
| GSE29001 | CDH16 | 1014 | 206517_at | -0.3939 | 0.0379 | |
| GSE38129 | CDH16 | 1014 | 206517_at | -0.2091 | 0.3625 | |
| GSE45670 | CDH16 | 1014 | 206517_at | 0.3742 | 0.3310 | |
| GSE53622 | CDH16 | 1014 | 105048 | -0.6377 | 0.0207 | |
| GSE53624 | CDH16 | 1014 | 105048 | -1.5573 | 0.0000 | |
| GSE63941 | CDH16 | 1014 | 206517_at | 0.1812 | 0.2105 | |
| GSE77861 | CDH16 | 1014 | 206517_at | 0.1786 | 0.7588 | |
| GSE97050 | CDH16 | 1014 | A_23_P100240 | 0.5718 | 0.1657 | |
| SRP007169 | CDH16 | 1014 | RNAseq | -1.5697 | 0.0068 | |
| SRP064894 | CDH16 | 1014 | RNAseq | -2.2179 | 0.0000 | |
| SRP133303 | CDH16 | 1014 | RNAseq | -0.3491 | 0.5823 | |
| SRP159526 | CDH16 | 1014 | RNAseq | -1.5008 | 0.1777 | |
| SRP219564 | CDH16 | 1014 | RNAseq | -0.9252 | 0.4476 | |
| TCGA | CDH16 | 1014 | RNAseq | 0.3488 | 0.6250 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by CDH16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDH16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDH16 | 1014 | 8 | 2 | 20 | |
| GSE20123 | CDH16 | 1014 | 8 | 2 | 20 | |
| GSE43470 | CDH16 | 1014 | 1 | 8 | 34 | |
| GSE46452 | CDH16 | 1014 | 38 | 1 | 20 | |
| GSE47630 | CDH16 | 1014 | 10 | 8 | 22 | |
| GSE54993 | CDH16 | 1014 | 2 | 4 | 64 | |
| GSE54994 | CDH16 | 1014 | 8 | 10 | 35 | |
| GSE60625 | CDH16 | 1014 | 4 | 0 | 7 | |
| GSE74703 | CDH16 | 1014 | 1 | 5 | 30 | |
| GSE74704 | CDH16 | 1014 | 5 | 1 | 14 | |
| TCGA | CDH16 | 1014 | 31 | 11 | 54 |
Total number of gains: 116; Total number of losses: 52; Total Number of normals: 320.
Somatic mutations of CDH16:
Generating mutation plots.
Highly correlated genes for CDH16:
Showing top 20/271 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDH16 | USH1G | 0.709863 | 4 | 0 | 4 |
| CDH16 | GJB2 | 0.699339 | 3 | 0 | 3 |
| CDH16 | ADRA1A | 0.697145 | 3 | 0 | 3 |
| CDH16 | SBSN | 0.673032 | 5 | 0 | 5 |
| CDH16 | A2ML1 | 0.663454 | 4 | 0 | 4 |
| CDH16 | BNIPL | 0.661771 | 4 | 0 | 4 |
| CDH16 | LYNX1 | 0.655356 | 4 | 0 | 4 |
| CDH16 | CYSRT1 | 0.645033 | 4 | 0 | 4 |
| CDH16 | DENND2C | 0.642687 | 5 | 0 | 5 |
| CDH16 | TMEM184A | 0.640209 | 3 | 0 | 3 |
| CDH16 | EFNA2 | 0.640176 | 3 | 0 | 3 |
| CDH16 | KCNK7 | 0.639228 | 11 | 0 | 10 |
| CDH16 | TMEM45B | 0.634646 | 4 | 0 | 4 |
| CDH16 | SPRR2A | 0.633786 | 3 | 0 | 3 |
| CDH16 | LINC01360 | 0.630601 | 3 | 0 | 3 |
| CDH16 | EVPLL | 0.629251 | 4 | 0 | 3 |
| CDH16 | KRT6C | 0.624992 | 3 | 0 | 3 |
| CDH16 | PAX7 | 0.621677 | 3 | 0 | 3 |
| CDH16 | S100A16 | 0.62128 | 4 | 0 | 4 |
| CDH16 | DUOXA1 | 0.613718 | 4 | 0 | 4 |
For details and further investigation, click here
