| Full name: dual oxidase maturation factor 1 | Alias Symbol: FLJ32334|NUMBIP|NIP|mol | ||
| Type: protein-coding gene | Cytoband: 15q21.1 | ||
| Entrez ID: 90527 | HGNC ID: HGNC:26507 | Ensembl Gene: ENSG00000140254 | OMIM ID: 612771 |
| Drug and gene relationship at DGIdb | |||
Expression of DUOXA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DUOXA1 | 90527 | 1554648_a_at | -1.2547 | 0.3298 | |
| GSE26886 | DUOXA1 | 90527 | 1555404_a_at | -1.1358 | 0.0000 | |
| GSE45670 | DUOXA1 | 90527 | 1554648_a_at | -0.3004 | 0.3353 | |
| GSE53622 | DUOXA1 | 90527 | 20672 | -0.5604 | 0.0004 | |
| GSE53624 | DUOXA1 | 90527 | 20672 | -0.7891 | 0.0000 | |
| GSE63941 | DUOXA1 | 90527 | 1555404_a_at | 0.7127 | 0.0369 | |
| GSE77861 | DUOXA1 | 90527 | 1555404_a_at | -0.6369 | 0.0128 | |
| GSE97050 | DUOXA1 | 90527 | A_33_P3410235 | 0.1814 | 0.8273 | |
| SRP007169 | DUOXA1 | 90527 | RNAseq | -2.6220 | 0.0000 | |
| SRP008496 | DUOXA1 | 90527 | RNAseq | -2.8042 | 0.0000 | |
| SRP064894 | DUOXA1 | 90527 | RNAseq | -2.0661 | 0.0000 | |
| SRP133303 | DUOXA1 | 90527 | RNAseq | -1.7177 | 0.0000 | |
| SRP159526 | DUOXA1 | 90527 | RNAseq | -2.4892 | 0.0000 | |
| SRP193095 | DUOXA1 | 90527 | RNAseq | -1.6215 | 0.0000 | |
| SRP219564 | DUOXA1 | 90527 | RNAseq | -2.7922 | 0.0092 | |
| TCGA | DUOXA1 | 90527 | RNAseq | 0.1822 | 0.3543 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by DUOXA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DUOXA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DUOXA1 | 90527 | 4 | 5 | 21 | |
| GSE20123 | DUOXA1 | 90527 | 4 | 5 | 21 | |
| GSE43470 | DUOXA1 | 90527 | 4 | 4 | 35 | |
| GSE46452 | DUOXA1 | 90527 | 3 | 7 | 49 | |
| GSE47630 | DUOXA1 | 90527 | 8 | 10 | 22 | |
| GSE54993 | DUOXA1 | 90527 | 5 | 5 | 60 | |
| GSE54994 | DUOXA1 | 90527 | 5 | 7 | 41 | |
| GSE60625 | DUOXA1 | 90527 | 4 | 0 | 7 | |
| GSE74703 | DUOXA1 | 90527 | 4 | 3 | 29 | |
| GSE74704 | DUOXA1 | 90527 | 2 | 3 | 15 | |
| TCGA | DUOXA1 | 90527 | 11 | 16 | 69 |
Total number of gains: 54; Total number of losses: 65; Total Number of normals: 369.
Somatic mutations of DUOXA1:
Generating mutation plots.
Highly correlated genes for DUOXA1:
Showing top 20/1196 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DUOXA1 | DUOX1 | 0.874609 | 9 | 0 | 9 |
| DUOXA1 | BTBD11 | 0.789094 | 8 | 0 | 7 |
| DUOXA1 | C6orf132 | 0.7791 | 8 | 0 | 7 |
| DUOXA1 | EVPL | 0.778028 | 9 | 0 | 8 |
| DUOXA1 | TGM1 | 0.775189 | 8 | 0 | 8 |
| DUOXA1 | CYSRT1 | 0.770886 | 6 | 0 | 6 |
| DUOXA1 | MALL | 0.76938 | 8 | 0 | 8 |
| DUOXA1 | KATNBL1 | 0.767581 | 4 | 0 | 4 |
| DUOXA1 | TMEM154 | 0.766145 | 8 | 0 | 7 |
| DUOXA1 | CLIC3 | 0.761736 | 6 | 0 | 6 |
| DUOXA1 | EPS8L1 | 0.759253 | 8 | 0 | 8 |
| DUOXA1 | DAPP1 | 0.752326 | 6 | 0 | 6 |
| DUOXA1 | CWH43 | 0.749771 | 6 | 0 | 6 |
| DUOXA1 | BNIPL | 0.74961 | 8 | 0 | 8 |
| DUOXA1 | MAST4 | 0.747389 | 6 | 0 | 6 |
| DUOXA1 | PKP3 | 0.746363 | 8 | 0 | 6 |
| DUOXA1 | NBEAL2 | 0.742648 | 8 | 0 | 8 |
| DUOXA1 | GPR157 | 0.741277 | 7 | 0 | 7 |
| DUOXA1 | PTK6 | 0.740222 | 8 | 0 | 7 |
| DUOXA1 | DENND2C | 0.738663 | 9 | 0 | 7 |
For details and further investigation, click here
