EVPLL

 

Full name: envoplakin like Alias Symbol: 
Type: protein-coding gene Cytoband: 17p11.2
Entrez ID: 645027 HGNC ID: HGNC:35236 Ensembl Gene: ENSG00000214860 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of EVPLL:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 EVPLL 645027 236933_at -0.7910 0.0626
GSE26886 EVPLL 645027 236933_at -1.0436 0.0000
GSE45670 EVPLL 645027 236933_at -0.2556 0.2318
GSE53622 EVPLL 645027 4459 -1.9875 0.0000
GSE53624 EVPLL 645027 43460 -1.9745 0.0000
GSE63941 EVPLL 645027 236933_at 0.3021 0.4077
GSE77861 EVPLL 645027 236933_at -0.3194 0.0364
GSE97050 EVPLL 645027 A_32_P141682 -0.3052 0.5176
SRP064894 EVPLL 645027 RNAseq -2.0324 0.0002
SRP133303 EVPLL 645027 RNAseq -2.4620 0.0000
SRP159526 EVPLL 645027 RNAseq -2.0144 0.0324
TCGA EVPLL 645027 RNAseq 0.2766 0.5988

Upregulated datasets: 0; Downregulated datasets: 6.  


 

Survival by EVPLL expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of EVPLL:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 EVPLL 645027 3 3 24
GSE20123 EVPLL 645027 3 4 23
GSE43470 EVPLL 645027 1 5 37
GSE46452 EVPLL 645027 34 1 24
GSE47630 EVPLL 645027 7 1 32
GSE54993 EVPLL 645027 3 3 64
GSE54994 EVPLL 645027 6 6 41
GSE60625 EVPLL 645027 4 0 7
GSE74703 EVPLL 645027 1 2 33
GSE74704 EVPLL 645027 2 1 17
TCGA EVPLL 645027 19 23 54

Total number of gains: 83; Total number of losses: 49; Total Number of normals: 356.  


 

Somatic mutations of EVPLL:

 

Generating mutation plots.

 

Highly correlated genes for EVPLL:

 

Showing top 20/1188 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
EVPLLTMEM400.780016707
EVPLLUPK3B0.776614303
EVPLLMAPK130.764121505
EVPLLEVPL0.763333707
EVPLLEPGN0.762729303
EVPLLENDOU0.762473707
EVPLLSPAG170.760398606
EVPLLUSH1G0.759332707
EVPLLGBP60.757606404
EVPLLALS2CL0.755551707
EVPLLVSIG10L0.752152707
EVPLLHS3ST60.751335606
EVPLLKLK110.751016706
EVPLLA2ML10.750891707
EVPLLCRNN0.750467606
EVPLLEHD30.749318707
EVPLLEPS8L20.747781606
EVPLLRAET1E0.747337606
EVPLLMAB21L30.747326505
EVPLLDHRS10.743591707

For details and further investigation, click here