| Full name: synaptosome associated protein 23 | Alias Symbol: SNAP23A|SNAP23B|HsT17016 | ||
| Type: protein-coding gene | Cytoband: 15q15.1-q15.2 | ||
| Entrez ID: 8773 | HGNC ID: HGNC:11131 | Ensembl Gene: ENSG00000092531 | OMIM ID: 602534 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SNAP23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNAP23 | 8773 | 209130_at | -0.1097 | 0.7858 | |
| GSE20347 | SNAP23 | 8773 | 209130_at | -0.1362 | 0.3137 | |
| GSE23400 | SNAP23 | 8773 | 209130_at | 0.0890 | 0.3419 | |
| GSE26886 | SNAP23 | 8773 | 209130_at | 0.0304 | 0.8806 | |
| GSE29001 | SNAP23 | 8773 | 209130_at | -0.0386 | 0.8840 | |
| GSE38129 | SNAP23 | 8773 | 209130_at | -0.1011 | 0.3137 | |
| GSE45670 | SNAP23 | 8773 | 209130_at | -0.0408 | 0.8074 | |
| GSE53622 | SNAP23 | 8773 | 57567 | 0.1170 | 0.0312 | |
| GSE53624 | SNAP23 | 8773 | 57567 | -0.1848 | 0.0168 | |
| GSE63941 | SNAP23 | 8773 | 209130_at | -0.4101 | 0.3159 | |
| GSE77861 | SNAP23 | 8773 | 209130_at | -0.1899 | 0.2973 | |
| GSE97050 | SNAP23 | 8773 | A_33_P3305974 | 0.2811 | 0.2591 | |
| SRP007169 | SNAP23 | 8773 | RNAseq | -0.5874 | 0.1001 | |
| SRP008496 | SNAP23 | 8773 | RNAseq | -0.5330 | 0.0008 | |
| SRP064894 | SNAP23 | 8773 | RNAseq | -0.0068 | 0.9713 | |
| SRP133303 | SNAP23 | 8773 | RNAseq | 0.1485 | 0.1966 | |
| SRP159526 | SNAP23 | 8773 | RNAseq | -0.2616 | 0.4721 | |
| SRP193095 | SNAP23 | 8773 | RNAseq | -0.2467 | 0.0250 | |
| SRP219564 | SNAP23 | 8773 | RNAseq | -0.3851 | 0.2015 | |
| TCGA | SNAP23 | 8773 | RNAseq | -0.0601 | 0.2095 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SNAP23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNAP23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNAP23 | 8773 | 4 | 5 | 21 | |
| GSE20123 | SNAP23 | 8773 | 4 | 6 | 20 | |
| GSE43470 | SNAP23 | 8773 | 4 | 5 | 34 | |
| GSE46452 | SNAP23 | 8773 | 3 | 7 | 49 | |
| GSE47630 | SNAP23 | 8773 | 8 | 11 | 21 | |
| GSE54993 | SNAP23 | 8773 | 4 | 6 | 60 | |
| GSE54994 | SNAP23 | 8773 | 5 | 7 | 41 | |
| GSE60625 | SNAP23 | 8773 | 4 | 0 | 7 | |
| GSE74703 | SNAP23 | 8773 | 4 | 4 | 28 | |
| GSE74704 | SNAP23 | 8773 | 3 | 3 | 14 | |
| TCGA | SNAP23 | 8773 | 11 | 17 | 68 |
Total number of gains: 54; Total number of losses: 71; Total Number of normals: 363.
Somatic mutations of SNAP23:
Generating mutation plots.
Highly correlated genes for SNAP23:
Showing top 20/342 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNAP23 | TMTC3 | 0.78937 | 3 | 0 | 3 |
| SNAP23 | PRDM10 | 0.765744 | 3 | 0 | 3 |
| SNAP23 | RAC1 | 0.747726 | 4 | 0 | 3 |
| SNAP23 | RB1 | 0.747505 | 3 | 0 | 3 |
| SNAP23 | IQGAP1 | 0.734314 | 4 | 0 | 4 |
| SNAP23 | CDIPT | 0.732818 | 3 | 0 | 3 |
| SNAP23 | CMC1 | 0.725506 | 3 | 0 | 3 |
| SNAP23 | SAMM50 | 0.724254 | 3 | 0 | 3 |
| SNAP23 | HOOK3 | 0.721952 | 4 | 0 | 4 |
| SNAP23 | ATG2B | 0.721556 | 3 | 0 | 3 |
| SNAP23 | ANXA7 | 0.719701 | 3 | 0 | 3 |
| SNAP23 | C9orf78 | 0.718963 | 3 | 0 | 3 |
| SNAP23 | THAP2 | 0.714664 | 4 | 0 | 4 |
| SNAP23 | C6orf62 | 0.713087 | 3 | 0 | 3 |
| SNAP23 | AP4E1 | 0.711894 | 4 | 0 | 3 |
| SNAP23 | MRPL45 | 0.707802 | 3 | 0 | 3 |
| SNAP23 | PLEKHM3 | 0.707012 | 4 | 0 | 4 |
| SNAP23 | HDDC3 | 0.704981 | 3 | 0 | 3 |
| SNAP23 | RPS6KA3 | 0.70457 | 3 | 0 | 3 |
| SNAP23 | CD163L1 | 0.698782 | 3 | 0 | 3 |
For details and further investigation, click here
