| Full name: solute carrier family 25 member 11 | Alias Symbol: OGC | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 8402 | HGNC ID: HGNC:10981 | Ensembl Gene: ENSG00000108528 | OMIM ID: 604165 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC25A11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC25A11 | 8402 | 207088_s_at | 0.1275 | 0.7319 | |
| GSE20347 | SLC25A11 | 8402 | 209003_at | 0.3374 | 0.0286 | |
| GSE23400 | SLC25A11 | 8402 | 209003_at | 0.2211 | 0.0006 | |
| GSE26886 | SLC25A11 | 8402 | 209003_at | 0.0222 | 0.9428 | |
| GSE29001 | SLC25A11 | 8402 | 209003_at | 0.2488 | 0.4252 | |
| GSE38129 | SLC25A11 | 8402 | 209003_at | 0.2203 | 0.0809 | |
| GSE45670 | SLC25A11 | 8402 | 207088_s_at | 0.2217 | 0.2150 | |
| GSE53622 | SLC25A11 | 8402 | 70575 | 0.3797 | 0.0000 | |
| GSE53624 | SLC25A11 | 8402 | 70575 | 0.4293 | 0.0000 | |
| GSE63941 | SLC25A11 | 8402 | 207088_s_at | 1.1647 | 0.0049 | |
| GSE77861 | SLC25A11 | 8402 | 207088_s_at | 0.0917 | 0.7465 | |
| GSE97050 | SLC25A11 | 8402 | A_23_P38497 | 0.4314 | 0.1603 | |
| SRP007169 | SLC25A11 | 8402 | RNAseq | -0.0910 | 0.7672 | |
| SRP008496 | SLC25A11 | 8402 | RNAseq | -0.1285 | 0.5037 | |
| SRP064894 | SLC25A11 | 8402 | RNAseq | 0.6345 | 0.0335 | |
| SRP133303 | SLC25A11 | 8402 | RNAseq | 0.0693 | 0.6569 | |
| SRP159526 | SLC25A11 | 8402 | RNAseq | 0.5258 | 0.0012 | |
| SRP193095 | SLC25A11 | 8402 | RNAseq | 0.1308 | 0.2195 | |
| SRP219564 | SLC25A11 | 8402 | RNAseq | 0.2231 | 0.5889 | |
| TCGA | SLC25A11 | 8402 | RNAseq | 0.0033 | 0.9482 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SLC25A11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC25A11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC25A11 | 8402 | 5 | 2 | 23 | |
| GSE20123 | SLC25A11 | 8402 | 5 | 3 | 22 | |
| GSE43470 | SLC25A11 | 8402 | 1 | 6 | 36 | |
| GSE46452 | SLC25A11 | 8402 | 34 | 1 | 24 | |
| GSE47630 | SLC25A11 | 8402 | 7 | 1 | 32 | |
| GSE54993 | SLC25A11 | 8402 | 4 | 3 | 63 | |
| GSE54994 | SLC25A11 | 8402 | 5 | 9 | 39 | |
| GSE60625 | SLC25A11 | 8402 | 4 | 0 | 7 | |
| GSE74703 | SLC25A11 | 8402 | 1 | 3 | 32 | |
| GSE74704 | SLC25A11 | 8402 | 3 | 1 | 16 | |
| TCGA | SLC25A11 | 8402 | 18 | 21 | 57 |
Total number of gains: 87; Total number of losses: 50; Total Number of normals: 351.
Somatic mutations of SLC25A11:
Generating mutation plots.
Highly correlated genes for SLC25A11:
Showing top 20/819 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC25A11 | PYCR2 | 0.737748 | 3 | 0 | 3 |
| SLC25A11 | CLEC12A | 0.736817 | 3 | 0 | 3 |
| SLC25A11 | IL2RA | 0.701058 | 3 | 0 | 3 |
| SLC25A11 | SLC35B2 | 0.68809 | 3 | 0 | 3 |
| SLC25A11 | NOP56 | 0.684128 | 3 | 0 | 3 |
| SLC25A11 | PFN1 | 0.680498 | 9 | 0 | 9 |
| SLC25A11 | SENP3 | 0.679727 | 10 | 0 | 10 |
| SLC25A11 | RNF126 | 0.679139 | 3 | 0 | 3 |
| SLC25A11 | HIBADH | 0.67608 | 3 | 0 | 3 |
| SLC25A11 | FAM86C1 | 0.675634 | 3 | 0 | 3 |
| SLC25A11 | EMC6 | 0.672241 | 7 | 0 | 7 |
| SLC25A11 | HEXA | 0.670012 | 3 | 0 | 3 |
| SLC25A11 | LTB | 0.663333 | 3 | 0 | 3 |
| SLC25A11 | SCO1 | 0.662581 | 4 | 0 | 4 |
| SLC25A11 | CCRL2 | 0.658095 | 3 | 0 | 3 |
| SLC25A11 | ITGB2 | 0.656406 | 3 | 0 | 3 |
| SLC25A11 | TAF2 | 0.655993 | 4 | 0 | 4 |
| SLC25A11 | CUL7 | 0.653094 | 5 | 0 | 5 |
| SLC25A11 | PTCD1 | 0.652578 | 3 | 0 | 3 |
| SLC25A11 | CHST11 | 0.652183 | 3 | 0 | 3 |
For details and further investigation, click here
