| Full name: solute carrier family 22 member 18 | Alias Symbol: BWR1A|TSSC5|ITM | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 5002 | HGNC ID: HGNC:10964 | Ensembl Gene: ENSG00000110628 | OMIM ID: 602631 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC22A18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC22A18 | 5002 | 204981_at | -0.5832 | 0.2928 | |
| GSE20347 | SLC22A18 | 5002 | 204981_at | -0.8799 | 0.0003 | |
| GSE23400 | SLC22A18 | 5002 | 204981_at | -0.1307 | 0.1076 | |
| GSE26886 | SLC22A18 | 5002 | 204981_at | 0.2027 | 0.4650 | |
| GSE29001 | SLC22A18 | 5002 | 204981_at | -0.5346 | 0.0057 | |
| GSE38129 | SLC22A18 | 5002 | 204981_at | -0.2818 | 0.2340 | |
| GSE45670 | SLC22A18 | 5002 | 204981_at | 0.0867 | 0.7780 | |
| GSE53622 | SLC22A18 | 5002 | 115418 | -0.3460 | 0.0162 | |
| GSE53624 | SLC22A18 | 5002 | 115418 | -0.3639 | 0.0003 | |
| GSE63941 | SLC22A18 | 5002 | 204981_at | -0.0490 | 0.9553 | |
| GSE77861 | SLC22A18 | 5002 | 204981_at | -0.2753 | 0.6012 | |
| GSE97050 | SLC22A18 | 5002 | A_23_P139260 | 0.3668 | 0.2499 | |
| SRP007169 | SLC22A18 | 5002 | RNAseq | -1.3459 | 0.0028 | |
| SRP008496 | SLC22A18 | 5002 | RNAseq | -1.8111 | 0.0000 | |
| SRP064894 | SLC22A18 | 5002 | RNAseq | 0.2721 | 0.3450 | |
| SRP133303 | SLC22A18 | 5002 | RNAseq | -0.2993 | 0.2428 | |
| SRP159526 | SLC22A18 | 5002 | RNAseq | -0.1810 | 0.6804 | |
| SRP193095 | SLC22A18 | 5002 | RNAseq | -0.7690 | 0.0037 | |
| SRP219564 | SLC22A18 | 5002 | RNAseq | 0.6655 | 0.2802 | |
| TCGA | SLC22A18 | 5002 | RNAseq | -0.0846 | 0.4429 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by SLC22A18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC22A18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC22A18 | 5002 | 1 | 11 | 18 | |
| GSE20123 | SLC22A18 | 5002 | 1 | 12 | 17 | |
| GSE43470 | SLC22A18 | 5002 | 1 | 10 | 32 | |
| GSE46452 | SLC22A18 | 5002 | 7 | 8 | 44 | |
| GSE47630 | SLC22A18 | 5002 | 4 | 12 | 24 | |
| GSE54993 | SLC22A18 | 5002 | 3 | 1 | 66 | |
| GSE54994 | SLC22A18 | 5002 | 1 | 12 | 40 | |
| GSE60625 | SLC22A18 | 5002 | 0 | 0 | 11 | |
| GSE74703 | SLC22A18 | 5002 | 1 | 8 | 27 | |
| GSE74704 | SLC22A18 | 5002 | 0 | 8 | 12 | |
| TCGA | SLC22A18 | 5002 | 8 | 39 | 49 |
Total number of gains: 27; Total number of losses: 121; Total Number of normals: 340.
Somatic mutations of SLC22A18:
Generating mutation plots.
Highly correlated genes for SLC22A18:
Showing top 20/457 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC22A18 | C1orf210 | 0.748854 | 3 | 0 | 3 |
| SLC22A18 | MARVELD2 | 0.702105 | 3 | 0 | 3 |
| SLC22A18 | FAM110C | 0.697562 | 5 | 0 | 4 |
| SLC22A18 | RDH12 | 0.695757 | 3 | 0 | 3 |
| SLC22A18 | B4GALNT3 | 0.681977 | 3 | 0 | 3 |
| SLC22A18 | DNASE1L1 | 0.679594 | 4 | 0 | 3 |
| SLC22A18 | TMEM45B | 0.678321 | 3 | 0 | 3 |
| SLC22A18 | DMKN | 0.678162 | 4 | 0 | 4 |
| SLC22A18 | DUOXA1 | 0.675548 | 4 | 0 | 4 |
| SLC22A18 | USP43 | 0.659491 | 3 | 0 | 3 |
| SLC22A18 | OTOR | 0.656446 | 3 | 0 | 3 |
| SLC22A18 | CERS3 | 0.651895 | 4 | 0 | 3 |
| SLC22A18 | GJB6 | 0.650245 | 4 | 0 | 3 |
| SLC22A18 | FAM83G | 0.648708 | 5 | 0 | 4 |
| SLC22A18 | KLK11 | 0.643252 | 7 | 0 | 6 |
| SLC22A18 | CDRT1 | 0.640066 | 3 | 0 | 3 |
| SLC22A18 | HSBP1L1 | 0.639365 | 3 | 0 | 3 |
| SLC22A18 | CES2 | 0.636085 | 5 | 0 | 4 |
| SLC22A18 | TGM3 | 0.634293 | 5 | 0 | 4 |
| SLC22A18 | SCEL | 0.633813 | 5 | 0 | 4 |
For details and further investigation, click here
