| Full name: ETS homologous factor | Alias Symbol: ESE3|ESEJ | ||
| Type: protein-coding gene | Cytoband: 11p13 | ||
| Entrez ID: 26298 | HGNC ID: HGNC:3246 | Ensembl Gene: ENSG00000135373 | OMIM ID: 605439 |
| Drug and gene relationship at DGIdb | |||
Expression of EHF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EHF | 26298 | 225645_at | -0.5109 | 0.3415 | |
| GSE20347 | EHF | 26298 | 219850_s_at | -2.8229 | 0.0000 | |
| GSE23400 | EHF | 26298 | 219850_s_at | -2.1044 | 0.0000 | |
| GSE26886 | EHF | 26298 | 225645_at | -2.6082 | 0.0000 | |
| GSE29001 | EHF | 26298 | 219850_s_at | -2.1748 | 0.0021 | |
| GSE38129 | EHF | 26298 | 219850_s_at | -2.0761 | 0.0026 | |
| GSE45670 | EHF | 26298 | 225645_at | -0.3598 | 0.1167 | |
| GSE53622 | EHF | 26298 | 30422 | -1.7170 | 0.0000 | |
| GSE53624 | EHF | 26298 | 30422 | -2.5943 | 0.0000 | |
| GSE63941 | EHF | 26298 | 225645_at | 5.0239 | 0.0163 | |
| GSE77861 | EHF | 26298 | 225645_at | -1.5084 | 0.0326 | |
| GSE97050 | EHF | 26298 | A_23_P203540 | -0.0520 | 0.9707 | |
| SRP007169 | EHF | 26298 | RNAseq | -3.6136 | 0.0000 | |
| SRP008496 | EHF | 26298 | RNAseq | -3.3289 | 0.0000 | |
| SRP064894 | EHF | 26298 | RNAseq | -3.1223 | 0.0000 | |
| SRP133303 | EHF | 26298 | RNAseq | -2.0541 | 0.0000 | |
| SRP159526 | EHF | 26298 | RNAseq | -2.9824 | 0.0000 | |
| SRP193095 | EHF | 26298 | RNAseq | -2.1296 | 0.0000 | |
| SRP219564 | EHF | 26298 | RNAseq | -2.5289 | 0.0313 | |
| TCGA | EHF | 26298 | RNAseq | 0.0307 | 0.8743 |
Upregulated datasets: 1; Downregulated datasets: 15.
Survival by EHF expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EHF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EHF | 26298 | 2 | 6 | 22 | |
| GSE20123 | EHF | 26298 | 2 | 5 | 23 | |
| GSE43470 | EHF | 26298 | 4 | 4 | 35 | |
| GSE46452 | EHF | 26298 | 7 | 5 | 47 | |
| GSE47630 | EHF | 26298 | 3 | 10 | 27 | |
| GSE54993 | EHF | 26298 | 3 | 2 | 65 | |
| GSE54994 | EHF | 26298 | 3 | 10 | 40 | |
| GSE60625 | EHF | 26298 | 0 | 0 | 11 | |
| GSE74703 | EHF | 26298 | 4 | 2 | 30 | |
| GSE74704 | EHF | 26298 | 0 | 3 | 17 | |
| TCGA | EHF | 26298 | 15 | 23 | 58 |
Total number of gains: 43; Total number of losses: 70; Total Number of normals: 375.
Somatic mutations of EHF:
Generating mutation plots.
Highly correlated genes for EHF:
Showing top 20/1370 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EHF | CXCR2 | 0.797938 | 10 | 0 | 10 |
| EHF | TMEM40 | 0.7914 | 13 | 0 | 13 |
| EHF | VSIG10L | 0.790554 | 7 | 0 | 7 |
| EHF | BNIPL | 0.790275 | 7 | 0 | 7 |
| EHF | RBM47 | 0.785824 | 13 | 0 | 13 |
| EHF | RAB27B | 0.784922 | 11 | 0 | 10 |
| EHF | UPK3B | 0.784333 | 3 | 0 | 3 |
| EHF | DENND2D | 0.783462 | 11 | 0 | 11 |
| EHF | MACC1 | 0.783255 | 7 | 0 | 7 |
| EHF | MPZL2 | 0.783028 | 13 | 0 | 12 |
| EHF | EPHA1 | 0.782946 | 12 | 0 | 12 |
| EHF | ZNF185 | 0.781535 | 13 | 0 | 12 |
| EHF | TMPRSS11E | 0.778734 | 12 | 0 | 12 |
| EHF | CDS1 | 0.778268 | 12 | 0 | 12 |
| EHF | HOPX | 0.778139 | 12 | 0 | 12 |
| EHF | EVPL | 0.777602 | 12 | 0 | 12 |
| EHF | CLCA4 | 0.77704 | 13 | 0 | 13 |
| EHF | CD24 | 0.772845 | 13 | 0 | 12 |
| EHF | KLK13 | 0.771084 | 12 | 0 | 12 |
| EHF | TMPRSS11B | 0.77102 | 8 | 0 | 8 |
For details and further investigation, click here
