| Full name: corneodesmosin | Alias Symbol: D6S586E | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 1041 | HGNC ID: HGNC:1802 | Ensembl Gene: ENSG00000204539 | OMIM ID: 602593 |
| Drug and gene relationship at DGIdb | |||
Expression of CDSN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDSN | 1041 | 206192_at | 0.6257 | 0.5911 | |
| GSE20347 | CDSN | 1041 | 206192_at | 0.2669 | 0.3102 | |
| GSE23400 | CDSN | 1041 | 206192_at | 0.1045 | 0.4074 | |
| GSE26886 | CDSN | 1041 | 206192_at | -0.2357 | 0.1076 | |
| GSE29001 | CDSN | 1041 | 206192_at | 0.7843 | 0.3204 | |
| GSE38129 | CDSN | 1041 | 206192_at | 0.1073 | 0.6391 | |
| GSE45670 | CDSN | 1041 | 206192_at | 1.6517 | 0.0082 | |
| GSE53622 | CDSN | 1041 | 88244 | 2.8902 | 0.0000 | |
| GSE53624 | CDSN | 1041 | 88244 | 2.8470 | 0.0000 | |
| GSE63941 | CDSN | 1041 | 206192_at | 0.3647 | 0.1843 | |
| GSE77861 | CDSN | 1041 | 206192_at | 0.2480 | 0.5232 | |
| GSE97050 | CDSN | 1041 | A_23_P350396 | 1.7488 | 0.1659 | |
| SRP133303 | CDSN | 1041 | RNAseq | 1.2605 | 0.0075 | |
| SRP219564 | CDSN | 1041 | RNAseq | 0.8110 | 0.2107 | |
| TCGA | CDSN | 1041 | RNAseq | 1.0857 | 0.0040 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by CDSN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDSN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDSN | 1041 | 5 | 1 | 24 | |
| GSE20123 | CDSN | 1041 | 5 | 1 | 24 | |
| GSE43470 | CDSN | 1041 | 5 | 1 | 37 | |
| GSE46452 | CDSN | 1041 | 1 | 10 | 48 | |
| GSE47630 | CDSN | 1041 | 7 | 3 | 30 | |
| GSE54993 | CDSN | 1041 | 2 | 1 | 67 | |
| GSE54994 | CDSN | 1041 | 11 | 4 | 38 | |
| GSE60625 | CDSN | 1041 | 0 | 1 | 10 | |
| GSE74703 | CDSN | 1041 | 5 | 0 | 31 | |
| GSE74704 | CDSN | 1041 | 2 | 0 | 18 | |
| TCGA | CDSN | 1041 | 17 | 16 | 63 |
Total number of gains: 60; Total number of losses: 38; Total Number of normals: 390.
Somatic mutations of CDSN:
Generating mutation plots.
Highly correlated genes for CDSN:
Showing top 20/277 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDSN | CSF3R | 0.739512 | 3 | 0 | 3 |
| CDSN | KCNV1 | 0.72947 | 3 | 0 | 3 |
| CDSN | SPRR4 | 0.718119 | 5 | 0 | 5 |
| CDSN | ASPRV1 | 0.70408 | 6 | 0 | 6 |
| CDSN | CCNA1 | 0.698664 | 5 | 0 | 5 |
| CDSN | SPRR2G | 0.698218 | 9 | 0 | 9 |
| CDSN | PHLDA2 | 0.684852 | 3 | 0 | 3 |
| CDSN | GJA3 | 0.665328 | 3 | 0 | 3 |
| CDSN | LINC01137 | 0.662469 | 5 | 0 | 5 |
| CDSN | KRTDAP | 0.659646 | 8 | 0 | 7 |
| CDSN | NOVA2 | 0.658082 | 3 | 0 | 3 |
| CDSN | PRR9 | 0.650778 | 7 | 0 | 5 |
| CDSN | PNPLA1 | 0.648636 | 4 | 0 | 3 |
| CDSN | FBXO22 | 0.646988 | 3 | 0 | 3 |
| CDSN | PRND | 0.644464 | 3 | 0 | 3 |
| CDSN | SRXN1 | 0.6419 | 3 | 0 | 3 |
| CDSN | CD40 | 0.635716 | 3 | 0 | 3 |
| CDSN | SNAPC1 | 0.624028 | 4 | 0 | 3 |
| CDSN | PLA2G4E | 0.623412 | 3 | 0 | 3 |
| CDSN | DRD5 | 0.623355 | 3 | 0 | 3 |
For details and further investigation, click here
