| Full name: carcinoembryonic antigen related cell adhesion molecule 6 | Alias Symbol: CD66c | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 4680 | HGNC ID: HGNC:1818 | Ensembl Gene: ENSG00000086548 | OMIM ID: 163980 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CEACAM6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CEACAM6 | 4680 | 211657_at | -2.1448 | 0.2333 | |
| GSE20347 | CEACAM6 | 4680 | 211657_at | -3.2575 | 0.0000 | |
| GSE23400 | CEACAM6 | 4680 | 211657_at | -2.3657 | 0.0000 | |
| GSE26886 | CEACAM6 | 4680 | 203757_s_at | -7.1361 | 0.0000 | |
| GSE29001 | CEACAM6 | 4680 | 211657_at | -3.4863 | 0.0004 | |
| GSE38129 | CEACAM6 | 4680 | 211657_at | -2.1430 | 0.0048 | |
| GSE45670 | CEACAM6 | 4680 | 211657_at | -0.7431 | 0.1299 | |
| GSE53622 | CEACAM6 | 4680 | 28222 | -2.9448 | 0.0000 | |
| GSE53624 | CEACAM6 | 4680 | 28222 | -3.4286 | 0.0000 | |
| GSE63941 | CEACAM6 | 4680 | 211657_at | 2.2671 | 0.3163 | |
| GSE77861 | CEACAM6 | 4680 | 211657_at | -1.8455 | 0.0106 | |
| GSE97050 | CEACAM6 | 4680 | A_23_P218442 | -0.6996 | 0.2999 | |
| SRP007169 | CEACAM6 | 4680 | RNAseq | -2.3042 | 0.3415 | |
| SRP008496 | CEACAM6 | 4680 | RNAseq | -3.3156 | 0.0098 | |
| SRP064894 | CEACAM6 | 4680 | RNAseq | -3.7719 | 0.0000 | |
| SRP133303 | CEACAM6 | 4680 | RNAseq | -2.3114 | 0.0000 | |
| SRP159526 | CEACAM6 | 4680 | RNAseq | -3.9226 | 0.0001 | |
| SRP193095 | CEACAM6 | 4680 | RNAseq | -2.0538 | 0.0000 | |
| SRP219564 | CEACAM6 | 4680 | RNAseq | -2.8949 | 0.0431 | |
| TCGA | CEACAM6 | 4680 | RNAseq | 0.3337 | 0.2995 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by CEACAM6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CEACAM6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CEACAM6 | 4680 | 4 | 4 | 22 | |
| GSE20123 | CEACAM6 | 4680 | 4 | 3 | 23 | |
| GSE43470 | CEACAM6 | 4680 | 3 | 11 | 29 | |
| GSE46452 | CEACAM6 | 4680 | 48 | 1 | 10 | |
| GSE47630 | CEACAM6 | 4680 | 9 | 5 | 26 | |
| GSE54993 | CEACAM6 | 4680 | 17 | 4 | 49 | |
| GSE54994 | CEACAM6 | 4680 | 7 | 12 | 34 | |
| GSE60625 | CEACAM6 | 4680 | 9 | 0 | 2 | |
| GSE74703 | CEACAM6 | 4680 | 3 | 7 | 26 | |
| GSE74704 | CEACAM6 | 4680 | 4 | 1 | 15 | |
| TCGA | CEACAM6 | 4680 | 15 | 15 | 66 |
Total number of gains: 123; Total number of losses: 63; Total Number of normals: 302.
Somatic mutations of CEACAM6:
Generating mutation plots.
Highly correlated genes for CEACAM6:
Showing top 20/1572 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CEACAM6 | CEACAM5 | 0.917994 | 13 | 0 | 13 |
| CEACAM6 | FUT3 | 0.844072 | 13 | 0 | 13 |
| CEACAM6 | EVPL | 0.843207 | 11 | 0 | 11 |
| CEACAM6 | C5orf66-AS1 | 0.839681 | 6 | 0 | 6 |
| CEACAM6 | CLCA4 | 0.836607 | 12 | 0 | 12 |
| CEACAM6 | CAPN14 | 0.834728 | 7 | 0 | 7 |
| CEACAM6 | CEACAM7 | 0.830883 | 13 | 0 | 12 |
| CEACAM6 | ECM1 | 0.830466 | 11 | 0 | 11 |
| CEACAM6 | FAM3D | 0.830178 | 9 | 0 | 9 |
| CEACAM6 | TPRG1 | 0.828403 | 6 | 0 | 6 |
| CEACAM6 | SCEL | 0.823311 | 13 | 0 | 12 |
| CEACAM6 | VSIG10L | 0.822043 | 7 | 0 | 7 |
| CEACAM6 | TMPRSS11B | 0.816516 | 8 | 0 | 8 |
| CEACAM6 | CLIC3 | 0.814387 | 10 | 0 | 9 |
| CEACAM6 | DUOX1 | 0.814243 | 11 | 0 | 11 |
| CEACAM6 | MAL | 0.812112 | 12 | 0 | 12 |
| CEACAM6 | TTC9 | 0.810273 | 13 | 0 | 13 |
| CEACAM6 | BLNK | 0.808436 | 10 | 0 | 10 |
| CEACAM6 | CYSRT1 | 0.807709 | 7 | 0 | 7 |
| CEACAM6 | SCNN1B | 0.807229 | 12 | 0 | 12 |
For details and further investigation, click here
